Protein Alignment Sin1 and AVO1

DIOPT Version :9

• Sequence 1: NP_610963.1
• Gene: Sin1 / 36604
• FlyBaseID: FBgn0033935
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_014563.1
• Gene: AVO1 / 854076
• SGDID: S000005438
• Length: 1176
• Species: Saccharomyces cerevisiae
• Alignment Length: 645
• Identity: 125/645 - (19%)
• Similarity: 221/645 - (34%)
• Gaps: 178/645 - (27%)

  Fly     4 YSNQHWLLSHIRNSFISTDDTG--MCETVMLSDDMPKH----YLRKFGNSGAGGDHYHWRRAHKT 62
            ||.:.:     .|:..||.::|  ..::.|.::.:|.|    .::|:|       .||
Yeast   459 YSEERY-----SNNDSSTMESGEMSLDSDMQTNTIPSHSIPMSMQKYG-------IYH------- 504

  Fly    63 PPTGGGTTPERN-----------TRHPDAPLQEVDFICYPGLDLSDDEEDMSTHS---FDIQ--- 110
               |...:...|           :|||......|         :|..|....|.|   |.:.
Yeast   505 ---GDDDSTLNNVFDKAVLTMNSSRHPKERRDTV---------ISGKEPTSLTSSNRKFSVSSNL 557

  Fly   111 ---MYPEVGAHRFRSNTA----QKLEKL-DIAKRRAARIKSVNYQEEVQPPESDDFFKRKE---- 163
               ..|.:..|...|:||    .|..|: |....||.:......|:..||.......|..:
Yeast   558 TSTRSPLLRGHGRTSSTASSEHMKAPKVSDSVLHRARKSTLTLKQDHSQPSVPSSVHKSSKEGNI 622

  Fly   164 LPLSKAERVKNEPKANDDDLSDEGVQSQLTEQLAKSPKQAQNRFIE----FARFDGTSQVGMQTK 224
            |.....:.:.::|||           |||:....|..|:.....::    |:...|......::.
Yeast   623 LIEKTTDYLVSKPKA-----------SQLSNMFNKKKKRTNTNSVDVLEYFSFVCGDKVPNYESM 676

  Fly   225 RINVFLNMLPEPDRN-YPLKICVVATAKIQEVIGFVCYRTSLQ-YPD---------VPLKSLQHY 278
            .:.:::....:..|| :..|:...:|  |.|||||..:..|.: .||         ..:.:..::
Yeast   677 GLEIYIQASKKYKRNSFTTKVRKSST--IFEVIGFALFLYSTEKKPDNFEEDGLTVEDISNPNNF 739

  Fly   279 AL-YMTEDNDDMED-FPPLDNREPCSKFGFSQLTL-----AERRPLAPVTRVDYHSQLGSKSMTS 336
            :| .:.||.:..|| |..||.:........|::.|     ||:......|.:.:.:..|....::
Yeast   740 SLKIVDEDGEPFEDNFGKLDRKSTIQSISDSEVVLCKVDDAEKSQNEIETPLPFETGGGLMDAST 804

  Fly   337 VEDKTA--LSDAAVKALQNISLNGGTSDPGGGGGGGD------------SPHDNVKEYEKRLLNH 387
            ::..::  .:|..:..|.......|..|......|..            :|..|.......:.:|
Yeast   805 LDANSSHDTTDGTINQLSFYKPIIGNEDDIDKTNGSKIIDVTVYLYPNVNPKFNYTTISVLVTSH 869

  Fly   388 -NDMLEA--------PMHRTFRLNIIDKRFF--KSDVTLGISG-ERIEIDQCKNA------KFWP 434
             ||:|..        |  ..:.|.::.|.:.  .:|..|.:.| .::|:...|:|      |..|
Yeast   870 INDILVKYCKMKNMDP--NEYALKVLGKNYILDLNDTVLRLDGINKVELISKKDARELHLEKMKP 932

  Fly   435 Q-KKPV--------STPIDFVAHCEILE--RRHLKA-----------LLRIWLKSNSSSPSFSTG 477
            . ||||        .||:       .||  ..:|||           ..::..|:...|..:..|
Yeast   933 DLKKPVLPTIQSNDLTPL-------TLEPLNSYLKADAGGAVAAIPENTKVTSKAKKISTKYKLG 990

  Fly   478 CTSAPINASVTTLNAGSGSGGIAHSPSSPGHSSGLFSSSNIRFKHYDFDTDTHTAEQIHN 537
            ......::||.: .:.|.:||:|       :.:|.|.:.|      ...:..|...|.||
Yeast   991 LAKQHSSSSVAS-GSVSTAGGLA-------NGNGFFKNKN------SSKSSLHGTLQFHN 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sin1	NP_610963.1	SIN1	18..164	CDD:283156	35/180 (19%)
		CRIM	189..316	CDD:293583	32/148 (22%)
		SIN1_PH	394..545	CDD:293584	38/175 (22%)
AVO1	NP_014563.1	CRIM	638..786	CDD:407188	32/149 (21%)
		PH_Avo1	1066..1172	CDD:270139

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344382
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3739
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004857
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13335
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1337
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.960