Protein Alignment Sin1 and mapkap1

DIOPT Version :10

• Sequence 1: NP_610963.1
• Gene: Sin1 / 36604
• FlyBaseID: FBgn0033935
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_001093676.1
• Gene: mapkap1 / 100101680
• XenbaseID: XB-GENE-478752
• Length: 520
• Species: Xenopus tropicalis
• Alignment Length: 624
• Identity: 164/624 - (26%)
• Similarity: 269/624 - (43%)
• Gaps: 175/624 - (28%)

  Fly     1 MATYSNQHWLLSHIRNSFISTDDTGMCETVMLSDDMPKHYLRKFGNSGAGGDHYHWRRAHKTPPT 65
            ||...|...:|:|||.|.:::|||||||.|::..|:.   |.|...|...|::....:::
 Frog     1 MAFLDNPLIILAHIRQSHVTSDDTGMCEMVLIDHDVD---LEKLYQSSVSGENSTQMQSN----- 57

  Fly    66 GGGTTPERNTRHPDAPLQEVDFICYPGLDLSDDEEDMSTHSFDIQMYPEVGAHRFRSNTAQKLEK 130
             ||.|.              .::....:|:        |.|:|..:       |.|||||||||:
 Frog    58 -GGETQ--------------GYVYSQSVDI--------TSSWDFGI-------RRRSNTAQKLER 92

  Fly   131 LDIAKRRAARIKSVNYQE---EVQPPESDDFFKRKELPLSKAERVKNEPKANDDDLSDEGVQSQL 192
            |...::...:.|:|.:::   .....|....|:||..    .||..|           :|.||.|
 Frog    93 LRKERQNQIKCKNVQWKDRNTSHSAEELSSLFERKNF----KERALN-----------QGKQSIL 142

  Fly   193 TEQLAKSPKQAQNRFIEFARFDGTSQVG-MQTKRINVFLNMLPEPDRNYPLKICVVATAKIQEVI 256
            :.:|.:.|.|..|.|.|:::|||...|| ..||:|:|:|:|....|:..|:.:..:|.||:.::|
 Frog   143 SVRLEQCPLQLNNPFNEYSKFDGKGHVGTTATKKIDVYLSMQTSQDKLLPMTVVTIANAKVHDLI 207

  Fly   257 GFVCYRTSLQYPDVPLK-SLQHYALYMTEDNDDME-DFPPLDNREPCSKFGFSQLTLAERRPLAP 319
            |.:|::.:.:..:..|. ::..:.|::.||:.::: ||||||:.||..|||||.|.|.|:
 Frog   208 GLICWQYTTEGREPKLNDNVDAFCLHIAEDDGEVDTDFPPLDSNEPIHKFGFSTLALVEK----- 267

  Fly   320 VTRVDYHSQ-LGSKSMTSVE------------DKTALS-----DAAVKALQNISLNGG------- 359
                 |.|. |.:|....|.            |.|.::     :.|:|..:....|.|
 Frog   268 -----YSSPGLAAKQSLFVRINAAHGFSLIQVDSTNVTMRDILEKALKRRKGSQRNSGPQYRLEK 327

  Fly   360 TSDPG---------------------GGGGGGDSPHDNVKEYEKRLLNHNDMLEAPMHRTFRLNI 403
            .|.|.                     .....|:.|.:  :|.:..:....|||.:..:::|::::
 Frog   328 QSQPNVPVDLDSTLENQNSLEFCLVRENSSRGEEPPE--EETQIDIATVQDMLSSHQYKSFKVSM 390

  Fly   404 IDKRFFKSDVTLGISGERIEIDQCKN----AKFWPQKKPVSTPIDFVAHCEILERRHLKALLRIW 464
            |.:..|.:||.||||||::|||...|    .|||.::||:|...|.:..|::.|.:
 Frog   391 IHRLRFTTDVQLGISGEKVEIDPVTNQKTSTKFWIKQKPISIDSDVLCACDLAEEK--------- 446

  Fly   465 LKSNSSSPSFSTGCTSAPINASVTTLNAGSGSGGIAHSPSSPGHSSGLFS---SSNIRFKHYDFD 526
                                                    ||.|:  :|.   .||..:||..|:
 Frog   447 ----------------------------------------SPSHA--MFKVTYLSNHDYKHLYFE 469

  Fly   527 TDTHTAEQIHNKLNCILEMRSSDLRREFLLQRDRKQEKR 565
            :|..|..:|..|:|.|||.|:|..|.::..|:.||..:|
 Frog   470 SDAATVNEIVLKVNYILESRASTARADYFAQKQRKLTRR 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sin1	NP_610963.1	SIN1	18..164	CDD:461648	37/148 (25%)
		CRIM	190..316	CDD:465326	47/128 (37%)
		SIN1_PH	395..545	CDD:465327	40/156 (26%)
mapkap1	NP_001093676.1	SIN1	18..129	CDD:461648	37/148 (25%)
		CRIM	140..266	CDD:465326	46/125 (37%)
		SIN1-type RBD. /evidence=ECO:0000255	279..353		9/73 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	310..333		5/22 (23%)
		PH_Avo1	383..490	CDD:270139	41/157 (26%)