DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17385 and D19B

DIOPT Version :9

Sequence 1:	NP_001286418.1	Gene:	CG17385 / 36603	FlyBaseID:	FBgn0033934	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_477297.1	Gene:	D19B / 38717	FlyBaseID:	FBgn0022699	Length:	774	Species:	Drosophila melanogaster

Alignment Length:	271	Identity:	71/271 - (26%)
Similarity:	109/271 - (40%)	Gaps:	59/271 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DETVANQFSCKRCDRTFRSKRDQTLHRQEVHNHNKTTYECKLCAKSFCNSGNLDRHMKVHNDVRP 73
            |::..|.....:..|...::||:  ||         ..:|.:|.:.|..:...:.|||.|||:.|
  Fly   227 DDSDGNPKDKPKRKRIPATERDR--HR---------LIDCHICHQKFKKAIRYEEHMKHHNDLLP 280

  Fly    74 FVCNI----------------------------------CSKAFAQAV----NLQRHYAVHSGER 100
            |.|.:                                  |:|:||:.|    :::|.:.|.:.:|
  Fly   281 FQCTVESCRKGFTTANGLRVHVEHAHTETSAMHPCTYEGCNKSFARPVLLSFHMKRVHKVDTPQR 345

  Fly   101 PFTCNFCNKSFTQQSNMKRHKMTHTGEK-PFRCQRCGRYFSQLVNLKKHKLGHLNAKPYQCNYCE 164
            .|.|..|.|.|...:.:|:|...||||: ||.|:.||:.|.....|:.|.|.|...|.:.|.||.
  Fly   346 DFPCTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFPINSVLRDHLLRHAGIKNHVCPYCG 410

  Fly   165 KGFTQLSNFKRHLQSHIKEGVDVDVPASIQAA---AALARERLESEQKPSFFECMVCRAIFDTFA 226
            .|.|....:.:|:.:|.|| ...:......|:   .|||.......:|...|.|..|...|.
  Fly   411 VGKTTRQEWNKHILTHTKE-KKYECRQCDHASHNKQALANHVKVVHEKRKDFACQYCGKTFG--- 471

  Fly   227 DYEKHEAKCHE 237
              :.|..|.||
  Fly   472 --KSHACKIHE 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17385	NP_001286418.1	COG5048	<13..181	CDD:227381	54/206 (26%)
		C2H2 Zn finger	18..39	CDD:275368	5/20 (25%)
		C2H2 Zn finger	48..68	CDD:275368	6/19 (32%)
		C2H2 Zn finger	76..96	CDD:275368	7/57 (12%)
		C2H2 Zn finger	104..124	CDD:275368	6/19 (32%)
		C2H2 Zn finger	132..148	CDD:275368	5/15 (33%)
		C2H2 Zn finger	160..180	CDD:275368	6/19 (32%)
D19B	NP_477297.1	zf-AD	12..83	CDD:214871
		C2H2 Zn finger	255..275	CDD:275368	6/19 (32%)
		C2H2 Zn finger	283..335	CDD:275368	6/51 (12%)
		C2H2 Zn finger	318..338	CDD:275368	6/19 (32%)
		COG5048	<347..512	CDD:227381	44/140 (31%)
		C2H2 Zn finger	349..369	CDD:275368	6/19 (32%)
		C2H2 Zn finger	378..398	CDD:275368	7/19 (37%)
		C2H2 Zn finger	406..426	CDD:275368	6/19 (32%)
		C2H2 Zn finger	434..455	CDD:275368	4/20 (20%)
		C2H2 Zn finger	463..483	CDD:275368	7/23 (30%)
		C2H2 Zn finger	491..511	CDD:275368
		C2H2 Zn finger	586..607	CDD:275368
		C2H2 Zn finger	615..635	CDD:275368
		zf-H2C2_2	627..652	CDD:290200
		C2H2 Zn finger	643..663	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449749
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930