DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17385 and CG2116

DIOPT Version :9

Sequence 1:	NP_001286418.1	Gene:	CG17385 / 36603	FlyBaseID:	FBgn0033934	Length:	278	Species:	Drosophila melanogaster
Sequence 2:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster

Alignment Length:	342	Identity:	69/342 - (20%)
Similarity:	133/342 - (38%)	Gaps:	101/342 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VEFDE--TVANQFS-------------CKRCDRTFRSKRDQTLHRQEVHNHNKT-------TYEC 48
            |:|||  |...:||             |..|        ...:|:.::..|:||       .|.|
  Fly   229 VDFDEDSTPLVEFSMISDIMDEKLPVECGIC--------PDVMHKSKLSKHHKTHLVPGTNRYAC 285

  Fly    49 KLCAKSFCNSGNLDRHMKVHNDVRPFVCNICSKAFAQAVNLQRHYAVHSGERPFTCNFCNKSFTQ 113
            ..|.:::.:...|..|.:.|..:||:||.:|:..|:...:|:.|......|:...|..|.|:|.|
  Fly   286 IYCTETYRDCKYLAGHARRHMGIRPYVCELCTLYFSTKQDLRVHNQRRHLEKEHICEVCGKTFAQ 350

  Fly   114 QSNMKRHK-MTHTGEKPFRCQRCGRYFSQLVNLKKH----------------------------- 148
            .:.:|||: .||..::.|:|:.|.:.:.:..:|::|
  Fly   351 NTQLKRHREATHEKKRRFQCEYCQKAYYKNFSLQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMAR 415

  Fly   149 --KLGHLNAKPYQCNYCEKGFTQLSNF---KRHLQ--SHIKEGVDVDVPASIQAAAALARERLES 206
              |..||:...|.|:.|::.||.:|.|   ||.:|  |:.:..|:.|.......:.:::...:..
  Fly   416 HRKEMHLSQGTYVCHLCQEEFTDISYFDAHKRSIQCRSNTRRFVNADGNREGSDSESISGRNMNG 480

  Fly   207 EQKPSFFECMVCRAIFDTFA----DYEKHEAKCHEDHE---------RAQLEVNQMSHMHPDDYL 258
            :...           :|...    :|::.:....||::         |..|:.::..::...||
  Fly   481 QDDD-----------YDGMGPLQEEYDEDDGLLVEDNQPEEQGSPSNRQYLDESEQQYVQLSDY- 533

  Fly   259 PMKFAVPDLDTHEIIIE 275
                     |...:::|
  Fly   534 ---------DDQHLLVE 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17385	NP_001286418.1	COG5048	<13..181	CDD:227381	52/224 (23%)
		C2H2 Zn finger	18..39	CDD:275368	3/20 (15%)
		C2H2 Zn finger	48..68	CDD:275368	4/19 (21%)
		C2H2 Zn finger	76..96	CDD:275368	5/19 (26%)
		C2H2 Zn finger	104..124	CDD:275368	8/20 (40%)
		C2H2 Zn finger	132..148	CDD:275368	3/15 (20%)
		C2H2 Zn finger	160..180	CDD:275368	9/24 (38%)
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	5/26 (19%)
		C2H2 Zn finger	285..305	CDD:275368	4/19 (21%)
		PHA00733	<308..357	CDD:177301	15/48 (31%)
		C2H2 Zn finger	313..334	CDD:275368	5/20 (25%)
		C2H2 Zn finger	341..362	CDD:275368	8/20 (40%)
		C2H2 Zn finger	370..388	CDD:275368	4/17 (24%)
		C2H2 Zn finger	400..418	CDD:275370	0/17 (0%)
		C2H2 Zn finger	429..447	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449767
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930