DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG17385 and ZNF383

DIOPT Version :9

Sequence 1:NP_001286418.1 Gene:CG17385 / 36603 FlyBaseID:FBgn0033934 Length:278 Species:Drosophila melanogaster
Sequence 2:NP_001332876.1 Gene:ZNF383 / 163087 HGNCID:18609 Length:475 Species:Homo sapiens


Alignment Length:224 Identity:78/224 - (34%)
Similarity:116/224 - (51%) Gaps:17/224 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 FSCKRCDRTFRSKRDQTLHRQEVHNHNKTTYECKLCAKSFCNSGNLDRHMKVHNDVRPFVCNICS 80
            |.||.|.:.|......:.| |.:|. .|..||||.|.|:|....||..|.::|...:|:.|.:|.
Human   226 FECKECGKAFSCSSYLSQH-QRIHT-GKKPYECKECGKAFSYCSNLIDHQRIHTGEKPYECKVCG 288

  Fly    81 KAFAQAVNLQRHYAVHSGERPFTCNFCNKSFTQQSNMKRHKMTHTGEKPFRCQRCGRYFSQLVNL 145
            |||.::..|.:|..:|:||:|:.|..|.|:|||.|.:.:|:..||||||:.|:.||:.||....|
Human   289 KAFTKSSQLFQHARIHTGEKPYECKECGKAFTQSSKLVQHQRIHTGEKPYECKECGKAFSSGSAL 353

  Fly   146 KKHKLGHLNAKPYQCNYCEKGFTQLSNFKRHLQSHIKE--------GVDVDVPASIQAAAALARE 202
            ..|:..|...|||.|..|.|.|||.|..::|.:.|..|        |     .|..|.:.....:
Human   354 TNHQRIHTGEKPYDCKECGKAFTQSSQLRQHQRIHAGEKPFECLECG-----KAFTQNSQLFQHQ 413

  Fly   203 RLESEQKPSFFECMVCRAIFDTFADYEKH 231
            |:.:::||  :||..|...|:..::..:|
Human   414 RIHTDEKP--YECNECGKAFNKCSNLTRH 440

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17385NP_001286418.1 COG5048 <13..181 CDD:227381 65/164 (40%)
C2H2 Zn finger 18..39 CDD:275368 6/20 (30%)
C2H2 Zn finger 48..68 CDD:275368 8/19 (42%)
C2H2 Zn finger 76..96 CDD:275368 7/19 (37%)
C2H2 Zn finger 104..124 CDD:275368 8/19 (42%)
C2H2 Zn finger 132..148 CDD:275368 6/15 (40%)
C2H2 Zn finger 160..180 CDD:275368 8/19 (42%)
ZNF383NP_001332876.1 KRAB 6..66 CDD:214630
zf-C2H2 170..192 CDD:395048
C2H2 Zn finger 172..192 CDD:275368
zf-H2C2_2 187..209 CDD:404364
C2H2 Zn finger 200..220 CDD:275368
zf-H2C2_2 212..237 CDD:404364 5/10 (50%)
C2H2 Zn finger 228..248 CDD:275368 6/20 (30%)
COG5048 <231..475 CDD:227381 75/219 (34%)
C2H2 Zn finger 256..276 CDD:275368 8/19 (42%)
C2H2 Zn finger 284..304 CDD:275368 7/19 (37%)
C2H2 Zn finger 312..332 CDD:275368 8/19 (42%)
C2H2 Zn finger 340..360 CDD:275368 7/19 (37%)
C2H2 Zn finger 368..388 CDD:275368 8/19 (42%)
C2H2 Zn finger 396..416 CDD:275368 4/24 (17%)
C2H2 Zn finger 424..444 CDD:275368 4/17 (24%)
C2H2 Zn finger 452..472 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.