DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17385 and ZNF358

DIOPT Version :9

Sequence 1:NP_001286418.1 Gene:CG17385 / 36603 FlyBaseID:FBgn0033934 Length:278 Species:Drosophila melanogaster
Sequence 2:NP_060553.4 Gene:ZNF358 / 140467 HGNCID:16838 Length:568 Species:Homo sapiens


Alignment Length:258 Identity:83/258 - (32%)
Similarity:115/258 - (44%) Gaps:46/258 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 FSCKRCDRTFRSKRDQTLHRQEVHNHNKTTYECKLCAKSFCNSGNLDRHMKVHNDVRPFVCNICS 80
            |||..|.|.||.....:.||: .|:..| .|.|..|.|||.:...|.:|..:|...||:.|..|.
Human   151 FSCPDCGRAFRRSSGLSQHRR-THSGEK-PYRCPDCGKSFSHGATLAQHRGIHTGARPYQCAACG 213

  Fly    81 KAFAQAVNLQRHYAVHSGE----------------------------RPFTCNFCNKSFTQQSNM 117
            |||.....|.:|.:.||||                            ||..|..|.|.|.|.|.:
Human   214 KAFGWRSTLLKHRSSHSGEKPHHCPVCGKAFGHGSLLAQHLRTHGGPRPHKCPVCAKGFGQGSAL 278

  Fly   118 KRHKMTHTGEKPFRCQRCGRYFSQLVNLKKHKLGHLNAKPYQCNYCEKGFTQLSNFKRHLQSHIK 182
            .:|..|||||:|:.|.:||:.|.|...|.:|:..|...:||:|.:|.|.|.|.||.:.||:.|..
Human   279 LKHLRTHTGERPYPCPQCGKAFGQSSALLQHQRTHTAERPYRCPHCGKAFGQSSNLQHHLRIHTG 343

  Fly   183 EGVDVDVP--------ASIQAAAALARERLESEQKPSFFECMVCRAIFDTFADYEKHEAKCHE 237
            |.     |        |..|::|.|....:.|.::|  :.|.:|...|...:...||: :.||
Human   344 ER-----PYACPHCSKAFGQSSALLQHLHVHSGERP--YRCQLCGKAFGQASSLTKHK-RVHE 398

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17385NP_001286418.1 COG5048 <13..181 CDD:227381 67/192 (35%)
C2H2 Zn finger 18..39 CDD:275368 7/20 (35%)
C2H2 Zn finger 48..68 CDD:275368 7/19 (37%)
C2H2 Zn finger 76..96 CDD:275368 7/19 (37%)
C2H2 Zn finger 104..124 CDD:275368 7/19 (37%)
C2H2 Zn finger 132..148 CDD:275368 6/15 (40%)
C2H2 Zn finger 160..180 CDD:275368 9/19 (47%)
ZNF358NP_060553.4 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..117
COG5048 <35..339 CDD:227381 66/189 (35%)
lambda-1 108..>174 CDD:212564 9/23 (39%)
zf-C2H2 151..173 CDD:278523 9/22 (41%)
C2H2 Zn finger 153..173 CDD:275368 7/20 (35%)
zf-H2C2_2 166..190 CDD:290200 10/25 (40%)
C2H2 Zn finger 181..201 CDD:275368 7/19 (37%)
zf-H2C2_2 194..216 CDD:290200 8/21 (38%)
C2H2 Zn finger 209..229 CDD:275368 7/19 (37%)
zf-H2C2_2 222..244 CDD:290200 6/21 (29%)
C2H2 Zn finger 237..257 CDD:275368 0/19 (0%)
zf-H2C2_2 250..272 CDD:290200 5/21 (24%)
C2H2 Zn finger 265..285 CDD:275368 7/19 (37%)
zf-H2C2_2 277..300 CDD:290200 10/22 (45%)
zf-C2H2_8 292..370 CDD:292531 26/82 (32%)
C2H2 Zn finger 293..313 CDD:275368 7/19 (37%)
zf-H2C2_2 305..328 CDD:290200 8/22 (36%)
C2H2 Zn finger 321..341 CDD:275368 9/19 (47%)
zf-H2C2_2 333..356 CDD:290200 6/27 (22%)
C2H2 Zn finger 349..369 CDD:275368 4/19 (21%)
zf-H2C2_2 361..384 CDD:290200 6/24 (25%)
zf-C2H2 375..397 CDD:278523 5/22 (23%)
C2H2 Zn finger 377..397 CDD:275368 5/20 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 448..568
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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