Protein Alignment CG10104 and NAPSA

DIOPT Version :9

• Sequence 1: NP_610961.1
• Gene: CG10104 / 36602
• FlyBaseID: FBgn0033933
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_004842.1
• Gene: NAPSA / 9476
• HGNCID: 13395
• Length: 420
• Species: Homo sapiens
• Alignment Length: 418
• Identity: 168/418 - (40%)
• Similarity: 229/418 - (54%)
• Gaps: 41/418 - (9%)

  Fly     7 LLPVLFILPVQFQHPVSCKLQLYRVPLRRFPSARHRFEKLGIRMDRLRLKYAEEVSHFRGEWNSA 71
            |.|:|.:||:....|...  .|.|:||.|....|.....|                  || |...
Human     7 LQPLLLLLPLLNVEPSGA--TLIRIPLHRVQPGRRILNLL------------------RG-WREP 50

  Fly    72 VK--------------STPLSNYLDAQYFGPITIGTPPQTFKVIFDTGSSNLWVPSATCASTMVA 122
            .:              ..|||||.|.||||.|.:|||||.|.|.||||||||||||..|....|.
Human    51 AELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVP 115

  Fly   123 CRVHNRYFAKRSTSHQVRGDHFAIHYGSGSLSGFLSTDTVRVAGLEIRDQTFAEATEMPGPIFLA 187
            |.:|:|:..|.|:|.|..|..|||.||:|.:.|.||.|.:.:.|::.....|.||...|..:|..
Human   116 CWLHHRFDPKASSSFQANGTKFAIQYGTGRVDGILSEDKLTIGGIKGASVIFGEALWEPSLVFAF 180

  Fly   188 AKFDGIFGLAYRSISMQRIKPPFYAMMEQGLLTKPIFSVYLSRNGEK-DGGAIFFGGSNPHYYTG 251
            |.||||.||.:..:|::.::||...::|||||.||:||.||:|:.|: |||.:..|||:|.:|..
Human   181 AHFDGILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIP 245

  Fly   252 NFTYVQVSHRAYWQVKMDSAVI-RNLELCQQGCEVIIDTGTSFLALPYDQAILINESIGGTPSSF 315
            ..|:|.|:..||||:.|:...: ..|.||.:||..|:|||||.:..|.::...::.:|||.|...
Human   246 PLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIPLLA 310

  Fly   316 GQFLVPCDSVPDLPKITFTLGGRRFFLESHEYVFRDIYQDRRICSSAFIAVDLPSPSGPLWILGD 380
            |::::.|..:|.||.::|.|||..|.|.:|:||.:......|:|.|.|.|:|:|.|:||.|||||
Human   311 GEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPAGPFWILGD 375

  Fly   381 VFLGKYYTEFD----MERHRIGFADARS 404
            ||||.|...||    ....|:|.|.||:
Human   376 VFLGTYVAVFDRGDMKSSARVGLARART 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10104	NP_610961.1	A1_Propeptide	28..54	CDD:285240	7/25 (28%)
		pepsin_retropepsin_like	76..400	CDD:299705	149/329 (45%)
		Asp	84..402	CDD:278455	144/323 (45%)
NAPSA	NP_004842.1	pepsin_retropepsin_like	72..399	CDD:299705	146/326 (45%)
		Asp	77..401	CDD:278455	144/323 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X163
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.890