Protein Alignment CG10104 and REN

DIOPT Version :9

• Sequence 1: NP_610961.1
• Gene: CG10104 / 36602
• FlyBaseID: FBgn0033933
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_000528.1
• Gene: REN / 5972
• HGNCID: 9958
• Length: 406
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 151/378 - (39%)
• Similarity: 231/378 - (61%)
• Gaps: 8/378 - (2%)

  Fly    30 RVPLRRFPSARHRFEKLGIRMDRLRLKYAEEVSHFRGEWNSAVKSTPLSNYLDAQYFGPITIGTP 94
            |:.|:|.||.|...::.|:.|.||..::::.:.  |....:...|..|:||:|.||:|.|.||||
Human    33 RIFLKRMPSIRESLKERGVDMARLGPEWSQPMK--RLTLGNTTSSVILTNYMDTQYYGEIGIGTP 95

  Fly    95 PQTFKVIFDTGSSNLWVPSATCASTMVACRVHNRYFAKRSTSHQVRGDHFAIHYGSGSLSGFLST 159
            ||||||:|||||||:||||:.|:....||..|..:.|..|:|::..|....:.|.:|::|||||.
Human    96 PQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQ 160

  Fly   160 DTVRVAGLEIRDQTFAEATEMPGPIFLAAKFDGIFGLAYRSISMQRIKPPFYAMMEQGLLTKPIF 224
            |.:.|.|:.: .|.|.|.||||...|:.|:|||:.|:.:...::.|:.|.|..::.||:|.:.:|
Human   161 DIITVGGITV-TQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVF 224

  Fly   225 SVYLSRNGEKD---GGAIFFGGSNPHYYTGNFTYVQVSHRAYWQVKMDS-AVIRNLELCQQGCEV 285
            |.|.:|:.|..   ||.|..|||:|.:|.|||.|:.:.....||::|.. :|..:..||:.||..
Human   225 SFYYNRDSENSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLA 289

  Fly   286 IIDTGTSFLALPYDQAILINESIGGTPSSFGQFLVPCDSVPDLPKITFTLGGRRFFLESHEYVFR 350
            ::|||.|:::........:.|::|.....| .::|.|:..|.||.|:|.|||:.:.|.|.:|||:
Human   290 LVDTGASYISGSTSSIEKLMEALGAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQ 353

  Fly   351 DIYQDRRICSSAFIAVDLPSPSGPLWILGDVFLGKYYTEFDMERHRIGFADAR 403
            :.|..:::|:.|..|:|:|.|:||.|.||..|:.|:|||||...:|||||.||
Human   354 ESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10104	NP_610961.1	A1_Propeptide	28..54	CDD:285240	9/23 (39%)
		pepsin_retropepsin_like	76..400	CDD:299705	135/327 (41%)
		Asp	84..402	CDD:278455	133/321 (41%)
REN	NP_000528.1	A1_Propeptide	33..>51	CDD:311771	6/17 (35%)
		renin_like	78..405	CDD:133154	137/328 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20151
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120302
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X163
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.790