DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10104 and CG5860

DIOPT Version :9

Sequence 1:	NP_610961.1	Gene:	CG10104 / 36602	FlyBaseID:	FBgn0033933	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_650622.1	Gene:	CG5860 / 42095	FlyBaseID:	FBgn0038506	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	327	Identity:	116/327 - (35%)
Similarity:	172/327 - (52%)	Gaps:	12/327 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 LSNYLDAQYFGPITIGTPPQTFKVIFDTGSSNLWVPSATCASTMVACRVHNRYFAKRSTSHQVRG 141
            |..:.:.:|:|.|.:|.|.|.|.|||||||||.|:||..|..:..||:.|.:|.:.||:|:...|
  Fly    56 LQTHNNMEYYGTIAMGNPRQNFTVIFDTGSSNTWLPSVNCPMSNSACQNHRKYNSSRSSSYIPDG 120

  Fly   142 DHFAIHYGSGSLSGFLSTDTVRVAGLEIRDQTFAEATEMPGPIFLAAKFDGIFGLAYRSISMQRI 206
            .:|.:.||||.:.|:||.||:.:||.|:...||.|:..:....|.:.||||:.||....:|....
  Fly   121 RNFTLRYGSGMVVGYLSKDTMHIAGAELPHFTFGESLFLQHFAFSSVKFDGLVGLGLGVLSWSNT 185

  Fly   207 KPPFYAMMEQGLLTKPIFSVYLSRNGEKDGGAIFFGGSNPHYYTGNFTYVQVSHRAYWQVKMDSA 271
            .|....:..|.||.|.:|||||.|    |...|.|||.:...:.|...||.||....|.:::..:
  Fly   186 TPFLELLCAQRLLEKCVFSVYLRR----DPREIVFGGFDESKFEGKLHYVPVSQWHTWSLQISKS 246

  Fly   272 VIRNLELCQQGCEVIIDTGTSFLALPYDQAILINESIGGTPSSFGQFLVPCDSVPDLPKITFTLG 336
            .:...::..:. ..|:|||||.:.:|......:..::.....: |.|:|.|.| ..||.|...:|
  Fly   247 SVGTKQIGGKS-NAILDTGTSLVLVPQQTYHNLLNTLSAKLQN-GYFVVACKS-GSLPNINILIG 308

  Fly   337 GRRFFLESHEYVFRDIYQDRRICSSAFIAVDLPSPSGPLWILGDVFLGKYYTEFDMERHRIGFAD 401
            .:.|.|.|.:|:. ::..||:   .|.:....|...| .|:|||:||.:|||.||....|||.|.
  Fly   309 DKVFPLTSSDYIM-EVLLDRK---PACVLAIAPINRG-FWVLGDIFLRRYYTVFDATEKRIGLAK 368

  Fly   402 AR 403
            |:
  Fly   369 AK 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10104	NP_610961.1	A1_Propeptide	28..54	CDD:285240
		pepsin_retropepsin_like	76..400	CDD:299705	114/322 (35%)
		Asp	84..402	CDD:278455	114/317 (36%)
CG5860	NP_650622.1	pepsin_retropepsin_like	61..368	CDD:299705	113/318 (36%)
CG5860	NP_650622.1	Asp	63..369	CDD:278455	114/317 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439947
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1684
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900