Protein Alignment CG10104 and Bace

DIOPT Version :9

• Sequence 1: NP_610961.1
• Gene: CG10104 / 36602
• FlyBaseID: FBgn0033933
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001285756.1
• Gene: Bace / 34182
• FlyBaseID: FBgn0032049
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 382
• Identity: 167/382 - (43%)
• Similarity: 225/382 - (58%)
• Gaps: 38/382 - (9%)

  Fly    27 QLYRVPL---RRFPSARHRF--EKLGIRMDRLRLKYAEEVSHFRGEWNSAVKSTPLSNYLDAQYF 86
            :|:|||:   :.|...|...  ||     ..||.||  ::...|     :|....|||.::..|:
  Fly    18 ELHRVPILKEQNFVKTRQNVLAEK-----SYLRTKY--QLPSLR-----SVDEEQLSNSMNMAYY 70

  Fly    87 GPITIGTPPQTFKVIFDTGSSNLWVPSATCASTMVACRVHNRYFAKRSTSHQVRGDHFAIHYGSG 151
            |.|:||||.|:|||:||:|||||||||.||.|.  ||..||:|.:..|:::...|:.|:|.||:|
  Fly    71 GAISIGTPAQSFKVLFDSGSSNLWVPSNTCKSD--ACLTHNQYDSSASSTYVANGESFSIQYGTG 133

  Fly   152 SLSGFLSTDTVRVAGLEIRDQTFAEATEMPGPIFLAAKFDGIFGLAYRSISMQRIKPPFYAMMEQ 216
            ||:|:||||||.|.||.|:.|||||:|..||..|..|.||||.|:||.|:::..:.||||.|:.|
  Fly   134 SLTGYLSTDTVDVNGLSIQSQTFAESTNEPGTNFNDANFDGILGMAYESLAVDGVAPPFYNMVSQ 198

  Fly   217 GLLTKPIFSVYLSRNGEKD-GGAIFFGGSNPHYYTGNFTYVQVSHRAYWQVKMDSAVIRNLELCQ 280
            ||:...:||.||:|:|... ||.:.||||:...|:|..|||.:|.:.|||..|..:.|....||.
  Fly   199 GLVDNSVFSFYLARDGTSTMGGELIFGGSDASLYSGALTYVPISEQGYWQFTMAGSSIDGYSLCD 263

  Fly   281 QGCEVIIDTGTSFLALPYDQAILINESIGGTPSSFGQFLVPCDSVPDLPKITFTLGGRRFFLESH 345
            . |:.|.|||||.:..||:..|.::|.:......:    :.|.||..||.:||.:||..|.|:..
  Fly   264 D-CQAIADTGTSLIVAPYNAYITLSEILNVGEDGY----LDCSSVSSLPDVTFNIGGTNFVLKPS 323

  Fly   346 EYVFRDIYQDRRICSSAF--IAVDLPSPSGPLWILGDVFLGKYYTEFDMERHRIGFA 400
            .|    |.|....|.|||  :..|       .|||||||:|:||||||:..:|||||
  Fly   324 AY----IIQSDGNCMSAFEYMGTD-------FWILGDVFIGQYYTEFDLGNNRIGFA 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10104	NP_610961.1	A1_Propeptide	28..54	CDD:285240	8/30 (27%)
		pepsin_retropepsin_like	76..400	CDD:299705	151/326 (46%)
		Asp	84..402	CDD:278455	150/320 (47%)
Bace	NP_001285756.1	pepsin_retropepsin_like	59..369	CDD:299705	151/327 (46%)
		Asp	68..371	CDD:278455	150/320 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455532
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1684
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	1	1.000	-	-		mtm978
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900