DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10104 and sxa1

DIOPT Version :9

Sequence 1:	NP_610961.1	Gene:	CG10104 / 36602	FlyBaseID:	FBgn0033933	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001342952.1	Gene:	sxa1 / 3361468	PomBaseID:	SPAC26A3.01	Length:	533	Species:	Schizosaccharomyces pombe

Alignment Length:	399	Identity:	95/399 - (23%)
Similarity:	150/399 - (37%)	Gaps:	104/399 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 YLDA-QYFGPITIGTPPQTFKVIFDTGSSNLWVPS---------------------------ATC 116
            |.|| .||..:|:|:..:.:.:..||||...||.:                           .|.
pombe    70 YTDAGGYFANLTLGSNERVYSLTLDTGSPYTWVTAKNITALSASEIWSDTDGVDAGRSTSDIRTN 134

  Fly   117 ASTMVACRVHNRYFAKRSTSHQVRGDHFAIHYGSGSLSGFLST--DTVRVAGLEIRDQTFAEATE 179
            |.|...|..::...|:|:.|               |..|||::  |...|.|..:.|..:.....
pombe   135 ACTNYTCFDYSSTTARRTNS---------------STIGFLASYGDNTTVLGYNMVDNAYFAGLT 184

  Fly   180 MPGPIF-LAAK-FD--------GIFGLAYRSISMQ-----------RIKPPFYA--MMEQGLLTK 221
            :||..| ||.: :|        ||.||   |::|.           ...||...  ::...::..
pombe   185 LPGFEFGLATREYDSSQISVTPGIIGL---SVAMTITGISSDDKVVAFTPPTIVDQLVSANVIDT 246

  Fly   222 PIFSVYLSRNGEKDGGAIFFGGSNPHYYTGNFTYVQVS---HRAYWQVKMDSAVIRN-------- 275
            |.|.:||:    :|.|.:.|||.:.....|:..:|.:|   ...::.|.::|..:.|
pombe   247 PAFGIYLN----EDVGELIFGGYDKAKINGSVHWVNISSSDDSTFYSVNLESITVTNSTSSNNVQ 307

  Fly   276 --------LELCQQGCEVIIDTGTSFLALPYDQAILINESIGGTPSSFGQFLVPCDSVPDLPKIT 332
                    :|:   ...|.:||||.::.||.|....|.:...|..|.:|..::.|||..|...|:
pombe   308 SSKRSSKDIEV---NTTVTLDTGTVYIYLPEDTVESIADQYQGIVSEYGYVVIYCDSFSDSDYIS 369

  Fly   333 FTLGGRRFFLESHE--YVFRDIYQDRRICSSAFIAVDLPSPSGPLWILGDVFLGKYYTEFDMERH 395
            |..|....|..|..  .::|.......||..|....|..|     ::||..||...|:.:|.:..
pombe   370 FNFGSDADFHVSVNDLVIYRQESTSGDICYLALFEGDTSS-----YLLGQYFLQYVYSIYDWDAQ 429

  Fly   396 RIGFADARS 404
            :||.|...|
pombe   430 KIGLAALNS 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10104	NP_610961.1	A1_Propeptide	28..54	CDD:285240
		pepsin_retropepsin_like	76..400	CDD:299705	93/393 (24%)
		Asp	84..402	CDD:278455	91/390 (23%)
sxa1	NP_001342952.1	Asp	75..436	CDD:306525	91/390 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	97	1.000	Domainoid score	I1884
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1684
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.920