Protein Alignment CG10104 and Ren2

DIOPT Version :9

• Sequence 1: NP_610961.1
• Gene: CG10104 / 36602
• FlyBaseID: FBgn0033933
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_112470.2
• Gene: Ren2 / 19702
• MGIID: 97899
• Length: 424
• Species: Mus musculus
• Alignment Length: 409
• Identity: 173/409 - (42%)
• Similarity: 253/409 - (61%)
• Gaps: 21/409 - (5%)

  Fly     1 MWLLVSL-LPVLFILP--VQFQHPVSCKLQLYRVPLRRFPSARHRFEKLGIRMDRLRLKYAEEVS 62
            :|.|:.| .|..|.||  ..|:          |:||::.||.|...|:.|:.|.||..::  :|.
Mouse    31 LWALLLLWSPCTFSLPTGTTFE----------RIPLKKMPSVREILEERGVDMTRLSAEW--DVF 83

  Fly    63 HFRGEWNSAVKSTPLSNYLDAQYFGPITIGTPPQTFKVIFDTGSSNLWVPSATCASTMVACRVHN 127
            ..|......:....|:|||::||:|.|.||||||||||||||||:||||||..|:...:||.:|:
Mouse    84 TKRSSLTDLISPVVLTNYLNSQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYLACGIHS 148

  Fly   128 RYFAKRSTSHQVRGDHFAIHYGSGSLSGFLSTDTVRVAGLEIRDQTFAEATEMPGPIFLAAKFDG 192
            .|.:..|:|:...||.|.||||||.:.||||.|:|.|.|:.: .|||.|.||:|...|:.|:|||
Mouse   149 LYESSDSSSYMENGDDFTIHYGSGRVKGFLSQDSVTVGGITV-TQTFGEVTELPLIPFMLAQFDG 212

  Fly   193 IFGLAYRSISMQRIKPPFYAMMEQGLLTKPIFSVYLSRNGEKDGGAIFFGGSNPHYYTGNFTYVQ 257
            :.|:.:.:.::..:.|.|..::.||:|.:.:||||.:|.....||.:..|||:|.:|.|:|.||.
Mouse   213 VLGMGFPAQAVGGVTPVFDHILSQGVLKEKVFSVYYNRGPHLLGGEVVLGGSDPEHYQGDFHYVS 277

  Fly   258 VSHRAYWQVKMDS-AVIRNLELCQQGCEVIIDTGTSFLALPYDQAILINESIGGTPSSFGQFLVP 321
            :|....||:.|.. :|..:..||::||||::|||:||::.|.....||.:::|.......:::|.
Mouse   278 LSKTDSWQITMKGVSVGSSTLLCEEGCEVVVDTGSSFISAPTSSLKLIMQALGAKEKRLHEYVVS 342

  Fly   322 CDSVPDLPKITFTLGGRRFFLESHEYVFRDIYQDRR--ICSSAFIAVDLPSPSGPLWILGDVFLG 384
            |..||.||.|:|.||||.:.|.|.:||.:  |.:||  :|:.|..|:|:|.|:||:|:||..|:.
Mouse   343 CSQVPTLPDISFNLGGRAYTLSSTDYVLQ--YPNRRDKLCTVALHAMDIPPPTGPVWVLGATFIR 405

  Fly   385 KYYTEFDMERHRIGFADAR 403
            |:|||||...:|||||.||
Mouse   406 KFYTEFDRHNNRIGFALAR 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10104	NP_610961.1	A1_Propeptide	28..54	CDD:285240	10/25 (40%)
		pepsin_retropepsin_like	76..400	CDD:299705	148/326 (45%)
		Asp	84..402	CDD:278455	146/320 (46%)
Ren2	NP_112470.2	A1_Propeptide	51..76	CDD:285240	10/34 (29%)
		renin_like	98..423	CDD:133154	150/327 (46%)
		Asp	105..423	CDD:278455	146/320 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X163
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.030