DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10104 and asp-13

DIOPT Version :9

Sequence 1:	NP_610961.1	Gene:	CG10104 / 36602	FlyBaseID:	FBgn0033933	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_505232.1	Gene:	asp-13 / 179247	WormBaseID:	WBGene00017881	Length:	389	Species:	Caenorhabditis elegans

Alignment Length:	341	Identity:	102/341 - (29%)
Similarity:	170/341 - (49%)	Gaps:	26/341 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 SAVKSTPLSNYLDAQYFGPITIGTPPQTFKVIFDTGSSNLWVPSATCASTMVACRVHNRYFAKRS 134
            :.|:||  ::|:..:|.|.||:|||.|.|.|:.||||:||.:|...|.:.....|:.|.   |.|
Worm    59 TVVQST--TDYVYYEYMGNITVGTPDQNFIVVLDTGSANLLIPGTNCTTYCEKKRLFNE---KAS 118

  Fly   135 TSHQVRGDHFAIHYGSGSLSGFLSTDTVRVAG-----LEIRDQTFAEATEMPGPIFLAAKFDGIF 194
            :::......:.|.|.||...|.|..|||::.|     |.| .:::....:..|..|..:..:|||
Worm   119 STYIATNRPWQIKYASGDAYGTLGIDTVKIGGSGEAQLAI-PRSYLGVADTVGSDFKWSPKEGIF 182

  Fly   195 GLAYRSISMQRIKPPFYAMMEQGLLTKPIFSVYLSRN---GEKDGGAIFFGGSNPHYYTGNFTYV 256
            |||:.::::..|.||....:.||||.:|:|:.:..:.   |....||..:||.:.::......|.
Worm   183 GLAFTALAVDNITPPIINAINQGLLDQPLFTTWFGQRGAPGTSASGAFTYGGLDKNHCGPVIGYA 247

  Fly   257 QVSHRAYWQVKMDSAVIRNLELCQQGCEVIIDTGTSFLALPYDQAILIN--ESIGGTPSSFGQ-F 318
            ::::..::|.:.....:.:. :.....|||.||.||||..|  ||.:.|  ::.|.|.....| |
Worm   248 ELTNARHFQFQATGFSLGSY-VSTTTYEVITDTATSFLCGP--QAAIDNLAKAAGATWDPTNQVF 309

  Fly   319 LVPCDSVPDLPKITFTLGGRRFFLESHEYVFRDIYQDRRICSSAFIAVDLPSPSGPLWILGDVFL 383
            .:|||:  |...|...:|...:.:.::.|:.:   .|...|..|.|..:. :..||.||||..|:
Worm   310 NIPCDA--DAGPIKMKIGQFNYVIRANNYILK---IDTNSCLFAAIPQNY-AGFGPSWILGGPFM 368

  Fly   384 GKYYTEFDMERHRIGF 399
            .:|....|:.:.|:||
Worm   369 RQYCNVHDIGQKRVGF 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10104	NP_610961.1	A1_Propeptide	28..54	CDD:285240
		pepsin_retropepsin_like	76..400	CDD:299705	99/335 (30%)
		Asp	84..402	CDD:278455	98/327 (30%)
asp-13	NP_505232.1	Asp	71..384	CDD:365818	96/325 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920