Protein Alignment CG10104 and Pgc

DIOPT Version :9

• Sequence 1: NP_610961.1
• Gene: CG10104 / 36602
• FlyBaseID: FBgn0033933
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_080249.2
• Gene: Pgc / 109820
• MGIID: 98909
• Length: 392
• Species: Mus musculus
• Alignment Length: 410
• Identity: 160/410 - (39%)
• Similarity: 227/410 - (55%)
• Gaps: 34/410 - (8%)

  Fly     2 WLLVSLLPVLFILPVQFQHPVSCKLQLYRVPLRRFPSARHRFEKLGIRMDRLR-------LKYAE 59
            |::|:||    .||:       .:..|.||||::..|.|...::.|:..|.|:       .||
Mouse     3 WMVVALL----CLPL-------LEAALIRVPLKKMKSIRETMKEQGVLKDFLKNHKYDPGQKY-- 54

  Fly    60 EVSHFRGEWNSAVKSTPLSNYLDAQYFGPITIGTPPQTFKVIFDTGSSNLWVPSATCASTMVACR 124
               ||....:.:|...|:: |:||.|:|.|:||||||.|.|:||||||||||.|..|.|.  ||.
Mouse    55 ---HFGKFGDYSVLYEPMA-YMDASYYGEISIGTPPQNFLVLFDTGSSNLWVSSVYCQSE--ACT 113

  Fly   125 VHNRYFAKRSTSHQVRGDHFAIHYGSGSLSGFLSTDTVRVAGLEIRDQTFAEATEMPGPIFLAAK 189
            .|.||...:|:::..:|..|::.||:|||:||...||:||..:::.:|.|..:...||..|:.|:
Mouse   114 THTRYNPSKSSTYYTQGQTFSLQYGTGSLTGFFGYDTLRVQSIQVPNQEFGLSENEPGTNFVYAQ 178

  Fly   190 FDGIFGLAYRSISMQRIKPPFYAMMEQGLLTKPIFSVYLSRNGEKDGGAIFFGGSNPHYYTGNFT 254
            ||||.||||..:|..........|:.:|.|::|:|.|||......:||.|.|||.:.:.|||..|
Mouse   179 FDGIMGLAYPGLSSGGATTALQGMLGEGALSQPLFGVYLGSQQGSNGGQIVFGGVDENLYTGELT 243

  Fly   255 YVQVSHRAYWQVKMDSAVIRNLE---LCQQGCEVIIDTGTSFLALPYDQAILINESIGGTPSSFG 316
            ::.|:...|||:.:|..:|.|..   ....||:.|:|||||.|.:|......:.::||.....:|
Mouse   244 WIPVTQELYWQITIDDFLIGNQASGWCSSSGCQGIVDTGTSLLVMPAQYLNELLQTIGAQEGEYG 308

  Fly   317 QFLVPCDSVPDLPKITFTLGGRRFFLESHEYVFRDIYQDRRICSSAFIAVDLPSPSG-PLWILGD 380
            |:.|.||||..||.:||.|.|.:|.|....|    |.|:...|.....::.|.:.|| |||||||
Mouse   309 QYFVSCDSVSSLPTLTFVLNGVQFPLSPSSY----IIQEEGSCMVGLESLSLNAESGQPLWILGD 369

  Fly   381 VFLGKYYTEFDMERHRIGFA 400
            |||..||..|||..:|:|.|
Mouse   370 VFLRSYYAVFDMGNNRVGLA 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10104	NP_610961.1	A1_Propeptide	28..54	CDD:285240	9/25 (36%)
		pepsin_retropepsin_like	76..400	CDD:299705	138/327 (42%)
		Asp	84..402	CDD:278455	135/321 (42%)
Pgc	NP_080249.2	A1_Propeptide	18..46	CDD:285240	10/27 (37%)
		pepsin_retropepsin_like	73..391	CDD:299705	137/323 (42%)
		Asp	75..390	CDD:278455	135/321 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1339
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830