DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10104 and LOC101733630

DIOPT Version :9

Sequence 1:	NP_610961.1	Gene:	CG10104 / 36602	FlyBaseID:	FBgn0033933	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_012817292.3	Gene:	LOC101733630 / 101733630	-ID:	-	Length:	343	Species:	Xenopus tropicalis

Alignment Length:	326	Identity:	157/326 - (48%)
Similarity:	221/326 - (67%)	Gaps:	2/326 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 YLDAQYFGPITIGTPPQTFKVIFDTGSSNLWVPSATCASTMVACRVHNRYFAKRSTSHQVRGDHF 144
            ||.|||:|.|.:|:|||.|.|:||||||||||||..|:...:||.:|::|.:.:|:::...|..|
Frog    18 YLQAQYYGEIGLGSPPQNFTVVFDTGSSNLWVPSVHCSMLDIACWMHHKYDSSKSSTYVKNGTAF 82

  Fly   145 AIHYGSGSLSGFLSTDTVRVAGLEIRDQTFAEATEMPGPIFLAAKFDGIFGLAYRSISMQRIKPP 209
            ||.||:|||||:||.|||.:..|.::.|.|.||.:.||..|:|||||||.|:||..||:..:.|.
Frog    83 AIQYGTGSLSGYLSKDTVTIGNLAVKGQMFGEAVKQPGVTFVAAKFDGILGMAYPVISVDGVPPV 147

  Fly   210 FYAMMEQGLLTKPIFSVYLSRNGE-KDGGAIFFGGSNPHYYTGNFTYVQVSHRAYWQVKMDS-AV 272
            |..:|.|.|:...|||.||:||.: :.||.:..||::|.||||:|.|:.|:.:||||:.||. .|
Frog   148 FDNIMAQKLVESNIFSFYLNRNPDTQPGGELLLGGTDPKYYTGDFHYLNVTRKAYWQIHMDQLGV 212

  Fly   273 IRNLELCQQGCEVIIDTGTSFLALPYDQAILINESIGGTPSSFGQFLVPCDSVPDLPKITFTLGG 337
            ...|.||:.|||||:|||||.:..|.::...:.::||..|...||::|.||.||.||.|:.||||
Frog   213 GDQLTLCKGGCEVIVDTGTSLITGPLEEVTALQKAIGAVPLIQGQYMVQCDKVPTLPVISLTLGG 277

  Fly   338 RRFFLESHEYVFRDIYQDRRICSSAFIAVDLPSPSGPLWILGDVFLGKYYTEFDMERHRIGFADA 402
            :.:.|...:|:.:...:...||.|.|:.:::|.|:||||||||||:|:||:.||....|:|||.|
Frog   278 QVYTLTGEQYIMKVSQRGSTICLSGFMGLNIPPPAGPLWILGDVFIGQYYSVFDRAYDRVGFAKA 342

  Fly   403 R 403
            :
Frog   343 K 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10104	NP_610961.1	A1_Propeptide	28..54	CDD:285240
		pepsin_retropepsin_like	76..400	CDD:299705	154/321 (48%)
		Asp	84..402	CDD:278455	153/319 (48%)
LOC101733630	XP_012817292.3	Cathepsin_D2	18..341	CDD:133157	155/322 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54317
OrthoDB	1	1.010	-	-		D1619495at2759
OrthoFinder	1	1.000	-	-		FOG0000066
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X163
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.030