Protein Alignment Dh44-R1 and calcrlb

DIOPT Version :10

• Sequence 1: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_001920035.3
• Gene: calcrlb / 567131
• ZFINID: ZDB-GENE-080924-1
• Length: 466
• Species: Danio rerio
• Alignment Length: 385
• Identity: 120/385 - (31%)
• Similarity: 190/385 - (49%)
• Gaps: 36/385 - (9%)

  Fly    30 SVELQCLVQEHIEASTYGNDSGHCLTQFDSILCWPRTARGTLAVLQCMDELQGIHYDSSKNATRF 94
            :.:.:|..:...:.:....|...|...:|..|||.....|..:...|.:...  .:|:|:.||:.
Zfish    47 TAQFECYQKIMKDTNHNKTDGSMCKRTWDGWLCWEYMEPGVTSAQHCPNYFD--DFDTSEVATKI 109

  Fly    95 CHANGTW-------EKYTNYDACAHLPAPESVPEFEVIVELPTIIYY---IGYTLSLVSLSLALI 149
            |..:|.|       ..::||..|    ..:|....:..:.|    ||   ||:.|||:||..:|.
Zfish   110 CTNSGHWFVHPESNRTWSNYTDC----RLKSNDHKKTALNL----YYLTLIGHGLSLISLFTSLG 166

  Fly   150 VFAYFKELRCLRNTIHANLFFTYIMSA----LFWILLLSVQISIRSGVGSCIALITLFHFFTLTN 210
            :|.|||.|.|.|.|:|.||||::::::    :|:..:.:.|....:...||...:.:.|:....|
Zfish   167 IFFYFKSLSCQRITLHKNLFFSFVLNSVITIIFFTCVANNQEVTEANPVSCKVSVFIHHYLLGCN 231

  Fly   211 FFWMLVEGLYLYMLVVKTFSGDNLRFNIYASIGWGGPALFVVTWAVAKSLTVTYSTPEKYEINCP 275
            :||||.||:||:.|:|.....:......|..:|||.|.:.....|:::|.        .|..||.
Zfish   232 YFWMLCEGIYLHTLIVVAVFAEKQHLMWYYLLGWGFPLIPAFIHAISRSY--------YYNDNCW 288

  Fly   276 WMQETHVDWIYQGPVCAVLIINLTFLLRIMWVLITKLRSANTVETRQYRKAAKALLVLIPLFGIT 340
            ....|.:.:|..||:||.|::||.|||.|:.||||||:..:..|:..|.:|.:|.|:|:||.||.
Zfish   289 ISSNTSLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESSVYMRAVRATLILVPLLGIQ 353

  Fly   341 YLVVLAGPSESGLMGHMFAVLRAVLLSTQGFSVSLFYCFLNSEVRNALRHHISTWRDTRT 400
            ||::...| :..|...:|.....:|:..||..|:..:||.||||:..||.|   |...||
Zfish   354 YLLLPYKP-DGRLASEIFIHTTNILMHYQGLLVATIFCFFNSEVQGVLRRH---WNQYRT 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	17/66 (26%)
		7tmB1_DH_R	126..394	CDD:320391	97/274 (35%)
		TM helix 1	128..153	CDD:320391	12/27 (44%)
		TM helix 2	162..184	CDD:320391	7/25 (28%)
		TM helix 3	197..224	CDD:320391	10/26 (38%)
		TM helix 4	236..256	CDD:320391	5/19 (26%)
		TM helix 5	279..308	CDD:320391	13/28 (46%)
		TM helix 6	322..349	CDD:320391	11/26 (42%)
		TM helix 7	356..381	CDD:320391	7/24 (29%)
calcrlb	XP_001920035.3	HRM	67..132	CDD:397086	16/66 (24%)
		7tmB1_calcitonin_R	143..415	CDD:341343	100/283 (35%)
		TM helix 1	145..170	CDD:341343	12/28 (43%)
		TM helix 2	179..201	CDD:341343	7/21 (33%)
		TM helix 3	218..245	CDD:341343	10/26 (38%)
		TM helix 4	257..277	CDD:341343	5/19 (26%)
		TM helix 5	292..321	CDD:341343	13/28 (46%)
		TM helix 6	335..362	CDD:341343	12/27 (44%)
		TM helix 7	368..393	CDD:341343	7/24 (29%)