Protein Alignment Dh44-R1 and calcr

DIOPT Version :10

• Sequence 1: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_073788004.1
• Gene: calcr / 560268
• ZFINID: ZDB-GENE-060503-420
• Length: 614
• Species: Danio rerio
• Alignment Length: 513
• Identity: 146/513 - (28%)
• Similarity: 235/513 - (45%)
• Gaps: 110/513 - (21%)

  Fly     6 HIDSVNASGSDPL---------LDLH-------NLDGIGESVELQCLVQ---------------- 38
            |..|:|.:.|..|         |.:|       .||...||.....::|
Zfish   120 HSASINKTWSHCLTFSKDKIKTLPVHGFSETETELDPTAESKVSPVVIQKAEERKMIIDGQYKCF 184

  Fly    39 EHIEASTYGNDSG-HCLTQFDSILCWPRTARGTLAVLQCMDELQGIHYDSSKNATRFCHANGTW- 101
            |.:......|.|| :|...:|..|||..|..||.....|.:..  ..:||::..|::|...|.|
Zfish   185 EKMNRDQPYNKSGLYCNRTWDGWLCWDDTPAGTFTSQYCPNYF--ADFDSTEKVTKYCDETGNWF 247

  Fly   102 ------EKYTNYDAC-AHLPAPESVPEFEVIVELPTIIYY---IGYTLSLVSLSLALIVFAYFKE 156
                  ..::||..| ||....         :::..|:||   :|:.||:|||.::|.:|.||:.
Zfish   248 RHPETNRTWSNYTLCIAHTKDK---------LKMAYILYYMAIVGHALSIVSLLISLAIFFYFRS 303

  Fly   157 LRCLRNTIHANLFFTYIMSALFWILLLSVQIS----IRSGVGSCIALITLFHFFTL-TNFFWMLV 216
            |.|.|.|:|.|||.:|::::.|.|:.|...::    ::....|| .::..||.:.| .|:||||.
Zfish   304 LSCQRITLHKNLFCSYVLNSAFTIVNLITVVNNPKVVQRNPISC-KVLHFFHMYMLGCNYFWMLC 367

  Fly   217 EGLYLYMLVVKTFSGDNLRFNIYASIGWGGPALFVVTWAVAKSLTVTYSTPEKY-EINCPWMQ-E 279
            ||:||:.|:|.....:....:.|..:|||.|.:.....|||:         :|| :.|| ||. |
Zfish   368 EGIYLHTLIVVAVFAEEQHLHWYYLLGWGFPLVPASIHAVAR---------KKYFDDNC-WMSVE 422

  Fly   280 THVDWIYQGPVCAVLIINLTFLLRIMWVLITKLRSANTVETRQYRKAAKALLVLIPLFGITYLVV 344
            ||:.::..||:.|.|::||.|||.|:.||:||||..:..|:..|.||.:|.|:|:||.||.::::
Zfish   423 THLLYVVHGPIMAALLVNLFFLLNIVRVLVTKLRDTHRAESNMYMKAVRATLILVPLLGIQFVII 487

  Fly   345 LAGPSESGLMGHMFAVLRAVLLSTQGFSVSLFYCFLNSEVRNALRHHISTWRDTRTIQLNQNRRY 409
            ...| |:.|.|.::..:..:|:..||..|:..:||.|.||:.||:..   |...:
Zfish   488 PWRP-ENRLAGEIYDYIMHILMHYQGLLVATIFCFFNGEVQGALKRQ---WMQYK---------- 538

  Fly   410 TTKSFSKGGGSPRAESMRPLTSYYGRGKRESCV--SSATTTTLVGQHAPLSLHRGSNN 465
                                 :.:|:.:||.|.  |::.|.|.:.:......|...|:
Zfish   539 ---------------------AQWGQRRREHCSMRSTSYTATSITEVPAFMFHHDCNS 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	18/67 (27%)
		7tmB1_DH_R	126..394	CDD:320391	100/277 (36%)
		TM helix 1	128..153	CDD:320391	11/27 (41%)
		TM helix 2	162..184	CDD:320391	8/21 (38%)
		TM helix 3	197..224	CDD:320391	12/27 (44%)
		TM helix 4	236..256	CDD:320391	5/19 (26%)
		TM helix 5	279..308	CDD:320391	13/28 (46%)
		TM helix 6	322..349	CDD:320391	10/26 (38%)
		TM helix 7	356..381	CDD:320391	6/24 (25%)
calcr	XP_073788004.1	None