Protein Alignment Dh44-R1 and adcyap1r1b

DIOPT Version :10

• Sequence 1: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_021327469.1
• Gene: adcyap1r1b / 555473
• ZFINID: ZDB-GENE-110127-1
• Length: 445
• Species: Danio rerio
• Alignment Length: 467
• Identity: 120/467 - (25%)
• Similarity: 209/467 - (44%)
• Gaps: 100/467 - (21%)

  Fly    53 CLTQFDSILCWPRTARGTLAVLQCMDELQGIHYDSSK--NATRFCHANGTWEKYTNY-DACAHLP 114
            |...:|::.||.....|.:..:.|.:..:.::.::::  ..:|.|...|..|...:| |.|   |
Zfish    54 CRWMWDNLTCWQPARLGQVVWMPCPELFEVMNDENNEFGKVSRNCTEYGWSEMVPHYVDVC---P 115

  Fly   115 APESVPEFEVIVELPTIIYYIGYTLSLVSLSLALIVFAYFKELRCLRNTIHANLFFTYIMSALFW 179
            ..|:....::.......:|.:||:.|||||:.|:::...|::|.|.||.||.|||.::|:.|
Zfish   116 FNENGTNPDMYYVSVKALYTVGYSTSLVSLTTAMVILCKFRKLHCTRNFIHMNLFVSFILRA--- 177

  Fly   180 ILLLSVQISIRSGV--------------GSCIALITLFHFFTLTNFFWMLVEGLYLYMLVVKTFS 230
                 :.:.|:.|:              ..|.|::..||:..|:|:||:.:|||||:.|:|:||.
Zfish   178 -----ISVFIKDGILYAEEDSNHCFIHTVECKAVMVFFHYCVLSNYFWLFIEGLYLFTLLVETFF 237

  Fly   231 GDNLRFNIYASIGWGGPALFVVTWAVAKSLTVTYSTPEKYEINCPWMQETHVDWIYQGPVCAVLI 295
            .:...|..|..||||.|.:.|..|||   |...:.....::||    ....:.|:.:|||.|.::
Zfish   238 PEKRYFYWYTIIGWGTPTICVTIWAV---LRAHFDNIGCWDIN----DNATIWWVIKGPVLASIM 295

  Fly   296 INLTFLLRIMWVLITKLRSANT--VETRQYRKAAKALLVLIPLFGITYLVVLAGPSESGLMGHMF 358
            ||....:.|:.:|:.||:|.:.  .|:..|.:.|::.|:|||||||.|.|....|.:......:
Zfish   296 INFILFIGIIIILVQKLQSPDIGGNESSIYLRLARSTLLLIPLFGIHYTVFAFTPEDVSKRERL- 359

  Fly   359 AVLRAVLLSTQGFSVSLFYCFLNSEVRNALRHHISTWRDTRTIQLNQNRRYTTKSFSKGGGSPRA 423
             |....|.|.|||.|::.|||||.||::.::....:|...|...::...|:
Zfish   360 -VFELGLGSFQGFVVAVLYCFLNGEVQSEIKRKWRSWTVNRYFAVDMKHRH-------------- 409

  Fly   424 ESMRPLTSYYGRGKRESCVSSATTTTLVGQHAPLSLHRGSNNALHTMPTLAANAMSSGSTLSVMP 488
                                                           |:||::.::.|:.||::.
Zfish   410 -----------------------------------------------PSLASSGVNGGTQLSILS 427

  Fly   489 RAISPLMRQGLE 500
            ::.|.:....|:
Zfish   428 KSSSQIRMSSLQ 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	13/61 (21%)
		7tmB1_DH_R	126..394	CDD:320391	94/283 (33%)
		TM helix 1	128..153	CDD:320391	9/24 (38%)
		TM helix 2	162..184	CDD:320391	8/21 (38%)
		TM helix 3	197..224	CDD:320391	12/26 (46%)
		TM helix 4	236..256	CDD:320391	9/19 (47%)
		TM helix 5	279..308	CDD:320391	8/28 (29%)
		TM helix 6	322..349	CDD:320391	12/26 (46%)
		TM helix 7	356..381	CDD:320391	10/24 (42%)
adcyap1r1b	XP_021327469.1	HRM	51..117	CDD:397086	14/65 (22%)
		7tm_GPCRs	127..394	CDD:475119	94/283 (33%)
		TM helix 1	130..154	CDD:320653	9/23 (39%)
		TM helix 2	163..184	CDD:320653	9/28 (32%)
		TM helix 3	204..226	CDD:320653	8/21 (38%)
		TM helix 4	245..261	CDD:320653	7/15 (47%)
		TM helix 5	279..302	CDD:320653	7/22 (32%)
		TM helix 6	329..351	CDD:320653	11/21 (52%)
		TM helix 7	356..381	CDD:320653	10/26 (38%)