DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dh44-R1 and CG15556

DIOPT Version :9

Sequence 1:	NP_610960.1	Gene:	Dh44-R1 / 36601	FlyBaseID:	FBgn0033932	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001247379.1	Gene:	CG15556 / 43681	FlyBaseID:	FBgn0039821	Length:	755	Species:	Drosophila melanogaster

Alignment Length:	348	Identity:	82/348 - (23%)
Similarity:	134/348 - (38%)	Gaps:	63/348 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 DSSKNATRFCHANGTWEKYTNYDAC-------AHLPAPESVPEFEVIVELPTIIYYIGYTLSLVS 143
            ::|.:....|||    :..|.:...       |.|...|.....:||..       :|.||||:.
  Fly   422 EASSHPVILCHA----DHLTQFTFLLGVSKMQAGLDTNEDDHSLDVITN-------VGLTLSLLG 475

  Fly   144 LSLALIVFAYFKELRCLRNT-IHANLFFTYIMSALFWILL----LSVQISIRSGVGSCIALITLF 203
            |.:..|..|.||..|.|.:| |..||.....:..||:::|    |..|:. :|....|..:..:.
  Fly   476 LLMIFITAAVFKSFRTLASTKILLNLCAALGLQLLFFLILSQSHLLEQLE-QSESERCTLVGAVM 539

  Fly   204 HFFTLTNFFWMLVEGLYLYMLVVKTFSGDNLRFNIYASIGWGGPALFVVTWA--VAKSLTVTYST 266
            .:..|..|.||.:.|...|...|:....::.|..|..|.        |..|.  :..:|.|.:..
  Fly   540 QYLLLVVFSWMFIIGFLQYQRYVRVIGVNHPRHYILMSA--------VAAWTLPLIPTLLVVFLE 596

  Fly   267 PEKYEINCPWMQETHVDW---IYQG----------PVCAVLIINLTFLLRIMWVLITKLRSANTV 318
            |..|..|     .:.:|:   .|..          |:..:.:.|...:..|.|.:.|.|...:.:
  Fly   597 PGSYRPN-----NSSMDYPILCYPSGYGLSLGVILPIGLITVANAILVGYISWSVYTALFKRDLI 656

  Fly   319 ETRQYRKAAKALLVLIPLFGITYLVVLAGPSESGLMGHMFAVLRAVLLSTQGFSVSLFYCFLNSE 383
                 .|.....::|..|.|||::..|....:   .|.:||.|..:..:.|||.:.|::...|.|
  Fly   657 -----FKQLGLFVLLFFLLGITWIFGLCTYFD---FGRIFAYLFCLTATLQGFVLFLYFIVFNKE 713

  Fly   384 VRNA---LRHHISTWRDTRTIQL 403
            .:.|   |..:.|..|:.:|||:
  Fly   714 NQRAWLGLCCNSSKKRNQQTIQM 736

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	5/32 (16%)
		7tmB1_DH_R	126..394	CDD:320391	67/290 (23%)
		TM helix 1	129..153	CDD:320391	7/23 (30%)
		TM helix 2	162..183	CDD:320391	7/25 (28%)
		TM helix 3	197..219	CDD:320391	4/21 (19%)
		TM helix 4	238..254	CDD:320391	3/15 (20%)
		TM helix 5	279..302	CDD:320391	4/35 (11%)
		TM helix 6	327..349	CDD:320391	6/21 (29%)
		TM helix 7	356..381	CDD:320391	7/24 (29%)
CG15556	NP_001247379.1	7tm_4	481..703	CDD:304433	56/243 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462181
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930