Protein Alignment Dh44-R1 and mthl10

DIOPT Version :9

• Sequence 1: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_788446.2
• Gene: mthl10 / 38057
• FlyBaseID: FBgn0035132
• Length: 585
• Species: Drosophila melanogaster
• Alignment Length: 593
• Identity: 119/593 - (20%)
• Similarity: 198/593 - (33%)
• Gaps: 225/593 - (37%)

  Fly     5 NHIDSVNASGSDPLLDLHNL---------------------DGIGESVELQCLVQEHIEASTYGN 48
            |..|:||.:|       |.|                     |.|..|:..:..|:||:..
  Fly    57 NFYDTVNLTG-------HRLFPNGSYDYYGTIVPAELVGTYDYIHSSLTERIEVREHVRG----- 109

  Fly    49 DSGHCLTQFDS---ILC-WPRTARGTLAVLQCMDELQGIHYDSSKNAT----------------- 92
                |:.:|.|   |.| |.:...         .|:.|...|.|.|.|
  Fly   110 ----CVCKFKSCLNICCPWRQVFN---------SEVDGCIIDHSDNRTWPDPPMLNITFRNESTI 161

  Fly    93 -------------RFC-------HANGTWEKYTNYDACAHLPAPESV----PEFEVIVELPTIIY 133
                         |.|       .....|:.|..::..:.|...:.:    .||.::   ||
  Fly   162 LVNMFTQFAIQSFRPCPKMFSLQPETNNWDDYLLFENGSMLRVDDKLLIRKNEFCMV---PT--- 220

  Fly   134 YIG-----YTL------------------------SLVSLSLALIVFAYFKELRCLRNTIHANLF 169
            |:.     ||:                        |:..:.|.:.|:....|||    ..|....
  Fly   221 YVNESDMFYTIHPANCDMQDDHSTVKIINSYAMMFSIPFMMLTIAVYLLIPELR----NQHGKSL 281

  Fly   170 FTYIM------SALFWILLLSVQISIRSGVGSCIALITLFHFFTLTNFFWMLVEGLYLYMLVVKT 228
            ..|::      |:|.::.|..|.   .:|| :|.......:||.:..:.|:.|....|:    ..
  Fly   282 VCYLIGLSVGYSSLCYVQLYQVD---ATGV-TCKVFGYTAYFFFMGAYMWLSVISFDLW----HN 338

  Fly   229 FSG--------DNLRFNIYASIGWGGPALFVVTWAVAKSLTVTYSTPEKYE------INCPWMQE 279
            |.|        :..||..|:...||...:|:.....|:.||   :.|...:      :.| |:..
  Fly   339 FRGTRGINRFQEKKRFLFYSLYSWGIALVFLAFTYCAQQLT---NLPANLKPGIGDGVYC-WLDM 399

  Fly   280 THVDW----IYQGPVCAVLIIN-LTFLL---------RIMWVLITKLRSANTVETRQYRKAAKA- 329
            :  :|    .:.||:.|:::.| :.|::         |.|..:|....|...:.|.:.::..:|
  Fly   400 S--NWAAMIYFYGPILAIVVANTIMFIMTAIKIHGVQREMARIIASENSTKNLRTEKDKRFYRAW 462

  Fly   330 -------LLVLIPLFGITYLVVLAGPSESGLMGHMFAVLRAVLLSTQGFSVSLFYCFLNSEVRNA 387
                   .|.|..:.|||:|..|.    |..:|           |.:|:| .|||.   |::.||
  Fly   463 SNYRFGLFLRLFLIMGITWLTELI----SYFVG-----------SDKGWS-KLFYI---SDLANA 508

  Fly   388 LRHHISTWRDTRTIQLNQNRRYTTKSFSKGGGSPRAESMRPLTSYYGRGKRESCVSSATTTTLVG 452
            ::..:       ...|     :..|...|...:.|..|:|.     |..:|:|..|:.||::.|
  Fly   509 MQGFL-------IFML-----FVMKKKVKHLITNRCSSVRD-----GSNQRQSQYSTKTTSSSV- 555

  Fly   453 QHAPLSLH 460
              |.||||
  Fly   556 --ANLSLH 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	16/100 (16%)
		7tmB1_DH_R	126..394	CDD:320391	69/338 (20%)
		TM helix 1	129..153	CDD:320391	8/52 (15%)
		TM helix 2	162..183	CDD:320391	4/26 (15%)
		TM helix 3	197..219	CDD:320391	4/21 (19%)
		TM helix 4	238..254	CDD:320391	4/15 (27%)
		TM helix 5	279..302	CDD:320391	6/27 (22%)
		TM helix 6	327..349	CDD:320391	8/29 (28%)
		TM helix 7	356..381	CDD:320391	6/24 (25%)
mthl10	NP_788446.2	Methuselah_N	56..236	CDD:284145	37/209 (18%)
		7tm_4	244..514	CDD:304433	64/313 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462236
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840