DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dh44-R1 and Cirl

DIOPT Version :9

Sequence 1:NP_610960.1 Gene:Dh44-R1 / 36601 FlyBaseID:FBgn0033932 Length:504 Species:Drosophila melanogaster
Sequence 2:NP_001260807.1 Gene:Cirl / 35846 FlyBaseID:FBgn0033313 Length:1711 Species:Drosophila melanogaster


Alignment Length:492 Identity:101/492 - (20%)
Similarity:173/492 - (35%) Gaps:153/492 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    97 ANGTWEKYTNYD----ACAHLPAPESVPEFEVIVEL---------------PTIIYYIGYTLSLV 142
            |||...:.||..    :|.||      ..|.:::::               ..|..||...:.:|
  Fly   721 ANGCSLESTNRTHSVCSCNHL------TNFAILMDVVD
EHQHSLFTMFDGNMRIFIYISIGICVV 779

  Fly   143 SLSLALIVFAYFKE--LRCLRNTIHANLFFTYIMSALFWIL-LLSVQISIRSGVGSCIALITLF- 203
            .:.:||:....|..  ::..|.:|:.:::...:...|.::| :...:.||..|      .||:| 
  Fly   780 FIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSIFCG------FITIFL 838

  Fly   204 HFFTLTNFFWMLVEGLYLYMLVVKTFSGDNL--------RFNIYASIGWGGPALFVVTWAVAKSL 260
            |...|:...|...|..:.|    .|.:.|.|        :.|.|..:.:|     :....||.||
  Fly   839 HCAILSGTAWFCYEAFHSY----STLTSDELLLEVDQTPKVNCYYLLSYG-----LSLSVVAISL 894

  Fly   261 TVTYSTPEKYEIN--CPWMQETHVDWIYQGPVCAVLI-----INLTFLLRIMWVLITKLRSANTV 318
            .:   .|..|..|  |..|:...:  .|...|..||:     |..|||   .|:::.: :|...:
  Fly   895 VI---DPSTYTQNDYCVLMEANAL--FYATFVIPVLVFFVAAIGYTFL---SWIIMCR-KSRTGL 950

  Fly   319 ETRQYRKAAKA----------LLVLIPLFGITYLVVLAGPSE---SGLMGHMFAVLRAVLLSTQG 370
            :|:::.:.|..          ||:|..::...|..:.....:   :.:.|:.|.....:|    |
  Fly   951 KTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLL----G 1011

  Fly   371 FSVSLFYCFLNSEVRNALRHHI--STWRDTRTIQLNQNRRYTTKSFSKG---GGSPRA------- 423
            ..:.:|:|..|.::|...|.::  ..|       |.:..|.:..|.|.|   |..|.|       
  Fly  1012 LYIFVFHCIQNEKIRREYRKYVRQHAW-------LPKCLRCSKTSISSGIVTGNGPTAGTLCSVS 1069

  Fly   424 -----------------------ESMRPLTSYYGRGKRESC-----------VSSATTTTL---- 450
                                   ::..|:|.....|....|           .|...|.||    
  Fly  1070 TSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQAPP 1134

  Fly   451 --VGQHAPLSLHRGS--NNALHTMPTLAANAMSSGST 483
              :|.|  :.|.|||  .:..|..||     .|:|||
  Fly  1135 QTLGGH--VVLERGSTLRSTGHASPT-----SSAGST 1164

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dh44-R1NP_610960.1 HRM 52..112 CDD:397086 6/18 (33%)
7tmB1_DH_R 126..394 CDD:320391 62/316 (20%)
TM helix 1 129..153 CDD:320391 6/23 (26%)
TM helix 2 162..183 CDD:320391 3/21 (14%)
TM helix 3 197..219 CDD:320391 7/22 (32%)
TM helix 4 238..254 CDD:320391 2/15 (13%)
TM helix 5 279..302 CDD:320391 7/27 (26%)
TM helix 6 327..349 CDD:320391 5/31 (16%)
TM helix 7 356..381 CDD:320391 5/24 (21%)
CirlNP_001260807.1 Gal_Lectin 33..113 CDD:280328
GAIN 453..680 CDD:293098
GPS 705..752 CDD:197639 9/36 (25%)
7tm_4 763..1014 CDD:304433 57/278 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45462220
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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