Protein Alignment Dh44-R1 and pth1r

DIOPT Version :10

• Sequence 1: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_571432.1
• Gene: pth1r / 30629
• ZFINID: ZDB-GENE-991123-8
• Length: 536
• Species: Danio rerio
• Alignment Length: 498
• Identity: 152/498 - (30%)
• Similarity: 233/498 - (46%)
• Gaps: 96/498 - (19%)

  Fly    44 STYGNDSGHCLTQFDSILCWPRTARGTLAVLQCMDELQGIHYDSSKNATRFCHANGTWE------ 102
            |.:....|.||.::|.|||||....|.:....|.:.:...::..  :|.|.|..|||||
Zfish    54 SKHKTSEGSCLPEWDGILCWPEGVPGKMVSTSCPEYIYDFNHKG--HAYRRCDLNGTWELASHNN 116

  Fly   103 -KYTNYDACA-HLPAPESVPEFEVIVELPTIIYYIGYTLSLVSLSLALIVFAYFKELRCLRNTIH 165
             .:.||..|| ..|......|.||...| .:||.:||::||.||.:|.::..||:.|.|.||.||
Zfish   117 KTWANYSECAKFFPHYNQNQEREVFDRL-YLIYTVGYSISLGSLMVATVILGYFRRLHCTRNYIH 180

  Fly   166 ANLFFTYIMSALFWILLLSVQISIRSG----------------------------VGSCIALITL 202
            .:||.::::.|   |.:....:.:.||                            :| |...:||
Zfish   181 MHLFLSFMLRA---ISIFVKDVVLYSGSALQEMERITVEDLKSITEAPPANKTQFIG-CKVAVTL 241

  Fly   203 FHFFTLTNFFWMLVEGLYLYMLVVKTFSGDNLRFNIYASIGWGGPALFVVTWAVAKSLTVTYSTP 267
            |.:|..||::|:|||||||:.|:..||..|......:..||||.||:||..||   |:..|.:..
Zfish   242 FLYFLATNYYWILVEGLYLHSLIFMTFFSDRKYLWGFTLIGWGVPAMFVTIWA---SVRATLADT 303

  Fly   268 EKYEINCPWMQETHVDWIYQGPVCAVLIINLTFLLRIMWVLITKLRSANT--VETR-QYRKAAKA 329
            |.::::.     .::.||.|.|:...:::|....|.|:.||.||||..|.  .:|| ||||..|:
Zfish   304 ECWDLSA-----GNLKWIVQIPILTAIVVNFLLFLNIIRVLATKLRETNAGRCDTRQQYRKLLKS 363

  Fly   330 LLVLIPLFGITYLVVLAGP--SESGLMGHMFAVLRAVLLSTQGFSVSLFYCFLNSEVRNALRHHI 392
            .|||:||||:.|:|.:|.|  ..||::..:......:..|.|||.|::.|||.|.||:..::
Zfish   364 TLVLMPLFGVHYIVFMAMPYTEVSGVLWQIQMHYEMLFNSVQGFFVAIIYCFCNGEVQAEIK--- 425

  Fly   393 STW-RDTRTIQLNQNRRYTTKSFSKGGGSPRAESMRPLTSYYGRGKRESCVSSATTTTLVGQHAP 456
            ..| |.|..:...:..|..:.::|.|          |:.|:             |:.|.|....|
Zfish   426 KAWNRRTLALDFKRKARSGSNTYSYG----------PMVSH-------------TSVTNVTARGP 467

  Fly   457 LSLH------RGSNNALHTMP------TLAANAM-SSGSTLSV 486
            |:||      ..:.|....:|      :::.|:: |||..|.:
Zfish   468 LALHLTNRLGHVTTNGHRNLPGYIKNGSVSENSIPSSGHELHI 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	22/67 (33%)
		7tmB1_DH_R	126..394	CDD:320391	102/300 (34%)
		TM helix 1	128..153	CDD:320391	10/24 (42%)
		TM helix 2	162..184	CDD:320391	7/21 (33%)
		TM helix 3	197..224	CDD:320391	14/26 (54%)
		TM helix 4	236..256	CDD:320391	9/19 (47%)
		TM helix 5	279..308	CDD:320391	7/28 (25%)
		TM helix 6	322..349	CDD:320391	16/28 (57%)
		TM helix 7	356..381	CDD:320391	8/24 (33%)
pth1r	NP_571432.1	HRM	60..125	CDD:397086	21/66 (32%)
		7tmB1_PTH1R	141..430	CDD:320650	103/304 (34%)
		TM helix 1	143..168	CDD:320650	10/25 (40%)
		TM helix 2	177..199	CDD:320650	7/24 (29%)
		TM helix 3	236..263	CDD:320650	14/26 (54%)
		TM helix 4	275..295	CDD:320650	10/22 (45%)
		TM helix 5	310..339	CDD:320650	7/33 (21%)
		TM helix 6	356..383	CDD:320650	15/26 (58%)
		TM helix 7	392..417	CDD:320650	8/24 (33%)