Protein Alignment Dh44-R1 and mthl12

DIOPT Version :9

• Sequence 1: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_731791.2
• Gene: mthl12 / 261599
• FlyBaseID: FBgn0045442
• Length: 488
• Species: Drosophila melanogaster
• Alignment Length: 431
• Identity: 86/431 - (19%)
• Similarity: 145/431 - (33%)
• Gaps: 142/431 - (32%)

  Fly    25 DGIGESVELQCLVQEHIEASTYGNDSGHCLTQFDSILCWPRTARGTLAVL--------------- 74
            ||:...::|..|                .||..|.:|..|     |||.|
  Fly   106 DGVKNEIKLTML----------------DLTMQDILLTDP-----TLAELNMIPQYNSTELLILR 149

  Fly    75 ---QCMDELQGI---HYDSSKNATRFCHANGTWEKYTNYDACAHLPAPESVPEFEVIVE------ 127
               |..||:..:   .|...|:.:...|.:.  |..:|...|.:   ||...:|...:.
  Fly   150 EQFQPCDEIVSLKRDEYTILKDGSILLHTSA--EILSNDQYCLY---PEIYSDFPETIRIINRRC 209

  Fly   128 ----LPTIIYYIGYTLSLVSLSLALIVFAYFKELRCLRNTIHANL---FFTYIMSALFWI----- 180
                :|.|.     .||::|:...::..|.:..:..|||.:...|   .|:..|....|.
  Fly   210 YRNVMPGIA-----QLSVISVVGFILTLAVYLSVEKLRNLLGKCLICSLFSMFMEYFIWTMDYFR 269

  Fly   181 LLLSVQISIRSGVGSCIALITLFHFFTLTNFFWMLVEGLYLYMLVVKTFSGDN-----LRFNIYA 240
            ||.|:          |.|...:.:||:::::.|..|...:|:.|    |:..|     .||.||.
  Fly   270 LLQSI----------CSAAGYMKYFFSMSSYLWFSVVSFHLWEL----FTSLNRHEPQYRFLIYN 320

  Fly   241 SIGWGGPALFVVTWAVAKSLTVTYSTPEKYEINCPWMQE---------------THVDWIYQGPV 290
            :..|...|:..|         |.:|..:.:| |.|...|               ....|.|..
  Fly   321 TFVWCTAAIPTV---------VIFSMNQMWE-NDPGKSEWLPLVGYFGCSVKDWNSSSWFYSH-- 373

  Fly   291 CAVLIIN----LTFLLRIMWVLITKL----------RSANTVE--TRQYRKAAKALLVLIPLFGI 339
            ..::|:|    :.|:|..:::...|.          |:...:|  .:.|.:..:..|::...:.:
  Fly   374 IPIVILNSFNVIMFVLTAIYIWKVKKGVKSFAQHDERNTTCLEFNVQTYIQFVRLFLIMGASWLL 438

  Fly   340 TYLVVLAGPSESGL----------MGHMFAVLRAVLLSTQG 370
            ..|..||..|...|          :...|.:|..|||..:|
  Fly   439 DQLTRLAEDSHLLLDTIVLNLTVYLNAAFGILIFVLLILKG 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	18/80 (23%)
		7tmB1_DH_R	126..394	CDD:320391	61/309 (20%)
		TM helix 1	129..153	CDD:320391	5/23 (22%)
		TM helix 2	162..183	CDD:320391	6/28 (21%)
		TM helix 3	197..219	CDD:320391	5/21 (24%)
		TM helix 4	238..254	CDD:320391	5/15 (33%)
		TM helix 5	279..302	CDD:320391	6/41 (15%)
		TM helix 6	327..349	CDD:320391	4/21 (19%)
		TM helix 7	356..381	CDD:320391	6/15 (40%)
mthl12	NP_731791.2	Methuselah_N	27..209	CDD:284145	25/128 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462232
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840