Protein Alignment Dh44-R1 and Dh44-R1

DIOPT Version :10

• Sequence 1: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_061496501.1
• Gene: Dh44-R1 / 1276158
• VectorBaseID: AGAMI1_000552
• Length: 484
• Species: Anopheles gambiae
• Alignment Length: 493
• Identity: 301/493 - (61%)
• Similarity: 366/493 - (74%)
• Gaps: 40/493 - (8%)

  Fly    24 LDGIGESVELQCLVQEHIEASTYGNDSGHCLTQFDSILCWPRTARGTLAVLQCMDELQGIHYDSS 88
            |.....|.|.:||::.|.:|.: ...||.|...||.|||||:|..||.|||.|.:|.:|:|||.:
Mosquito    20 LGAFENSTEFECLLRAHQDAQS-ETPSGGCPVDFDRILCWPKTDPGTWAVLPCFEEFKGVHYDVT 83

  Fly    89 KNATRFCHANGTWEKYTNYDACAHL--PAPESVPEFEVIVELPTIIYYIGYTLSLVSLSLALIVF 151
            :||||:||.||.|:.|::|.||.|:  |.|:       |||:.:||||.||.||||:||||:|||
Mosquito    84 QNATRYCHPNGRWDNYSHYAACHHVNEPPPD-------IVEISSIIYYTGYILSLVALSLAVIVF 141

  Fly   152 AYFKELRCLRNTIHANLFFTYIMSALFWILLLSVQISIRSGVG--SCIALITLFHFFTLTNFFWM 214
            .|||:|||||||||||||.|||:|||.||::|::|:|..|..|  ||:..:||.|:|||||||||
Mosquito   142 VYFKDLRCLRNTIHANLFITYILSALLWIIILTLQLSSGSSTGMTSCVIFVTLLHYFTLTNFFWM 206

  Fly   215 LVEGLYLYMLVVKTFSGDNLRFNIYASIGWGGPALFVVTWAVAKSLTVT-YSTPEKYEINCPWMQ 278
            ||||||||||||:||||||||||:||:|||||||:||:.||:||.:|:: ....:..||.|.||:
Mosquito   207 LVEGLYLYMLVVETFSGDNLRFNMYAAIGWGGPAIFVILWAIAKGITLSGQGKADTLEIECSWMR 271

  Fly   279 ETHVDWIYQGPVCAVLIINLTFLLRIMWVLITKLRSANTVETRQYRKAAKALLVLIPLFGITYLV 343
            |:.||||:||||||||||||.||:||||||||||||||||||||||||:|||||||||.||||||
Mosquito   272 ESVVDWIFQGPVCAVLIINLVFLIRIMWVLITKLRSANTVETRQYRKASKALLVLIPLLGITYLV 336

  Fly   344 VLAGPSESGLMGHMFAVLRAVLLSTQGFSVSLFYCFLNSEVRNALRHHISTWRDTRTIQLNQ--- 405
            |||.|:| |::..:||:.||:||||||.||||||||||||||.||||.:..|||.|.|:|.|
Mosquito   337 VLAAPAE-GVVSDIFAIARALLLSTQGLSVSLFYCFLNSEVRLALRHRLERWRDERNIRLGQVRQ 400

  Fly   406 -NRRYTTKSFSKGGG-SPRA--ESMRPLTSYYGRGKRESCVSSATTTTLVGQHAPLSLHRGSNNA 466
             :||:|...:::... |||:  ||.||||    ..|||||.||||||||:|.|:..|..||||.|
Mosquito   401 RSRRFTNSGYNQSKECSPRSRTESFRPLT----YNKRESCASSATTTTLLGPHSYPSAMRGSNGA 461

  Fly   467 LHTMPTLAANAMSSGSTLSVMPRAISPLMRQGLEENSV 504
            ||..              |::|||||||| |||:||||
Mosquito   462 LHMQ--------------SIVPRAISPLM-QGLDENSV 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	33/59 (56%)
		7tmB1_DH_R	126..394	CDD:320391	197/270 (73%)
		TM helix 1	128..153	CDD:320391	17/24 (71%)
		TM helix 2	162..184	CDD:320391	16/21 (76%)
		TM helix 3	197..224	CDD:320391	20/26 (77%)
		TM helix 4	236..256	CDD:320391	14/19 (74%)
		TM helix 5	279..308	CDD:320391	23/28 (82%)
		TM helix 6	322..349	CDD:320391	23/26 (88%)
		TM helix 7	356..381	CDD:320391	18/24 (75%)
Dh44-R1	XP_061496501.1	None