Protein Alignment Dh44-R1 and Pdfr

DIOPT Version :10

• Sequence 1: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_061496572.1
• Gene: Pdfr / 1274324
• VectorBaseID: AGAMI1_009150
• Length: 559
• Species: Anopheles gambiae
• Alignment Length: 489
• Identity: 159/489 - (32%)
• Similarity: 225/489 - (46%)
• Gaps: 84/489 - (17%)

  Fly    48 NDSGHCLTQFDSILCWPRTARGTLAVLQCMDELQGIHYDSSKNATRFCHANGTWE---------- 102
            |...:|...:|||||||.|. ..|.:.|......||  |:||.|.|.|.|.|.||
Mosquito    68 NTVPYCNWTWDSILCWPPTP-ANLTIRQRCPPAHGI--DTSKFAERRCSAEGQWEGKPGSPPTLH 129

  Fly   103 KYTNYDACAHLPAPESVPEFEV---------------IVELPTIIYYIGYTLSLVSLSLALIVFA 152
            .:|||..|.   :||.:..|..               |.|....:..:|::||||:|.::|::|.
Mosquito   130 GWTNYTPCY---SPEVIQLFRKLYASGSDDEANDKFDIAERTRTLETVGFSLSLVALIVSLVIFC 191

  Fly   153 YFKELRCLRNTIHANLFFTYIMSALFWILLLSVQISIRSG---------------VGSCIALITL 202
            .|:.||..|..||.|||...::..:..:.:...|..||||               :..|.|...|
Mosquito   192 KFRGLRNNRTRIHKNLFVAMVIQVVIRLTVYIDQAIIRSGGKKGNESSRQGIDNTLFLCEASYVL 256

  Fly   203 FHFFTLTNFFWMLVEGLYLYMLV-VKTFSGDNLRF--NIYASIGWGGPALFVVTWAVAKSLTVTY 264
            ..:.....|.||.:|||||:.:| |..|.|   ||  .:||.:|||||.:..:.||:   :|..|
Mosquito   257 LEYARTCMFMWMFIEGLYLHNVVTVTVFQG---RFPHKLYAIVGWGGPLILTIIWAI---ITAQY 315

  Fly   265 STPEKYEINCPW-MQETHVDWIYQGPVCAVLIINLTFLLRIMWVLITKLRSANTVETRQYRKAAK 328
            ...:|    |.| ...|...||.:||..|.:::|..|||.|:.|||.|||.::|.:..|.|||.:
Mosquito   316 IRQQK----CWWGYNLTPYYWILEGPRLAAVVLNFIFLLNIIRVLIVKLRQSHTSDVEQVRKAVR 376

  Fly   329 ALLVLIPLFGITYLVVL--AGPSESGLMGHMFAVLRAVLLSTQGFSVSLFYCFLNSEVRNALRHH 391
            |.:||:||.|||.::.:  |...::.|...:::.:...|.|.|||.::|.|||||.|||.||...
Mosquito   377 AAVVLVPLLGITNILNMTQAPLDKTALEFAIWSYVTHFLSSFQGFFIALLYCFLNGEVRTALMKS 441

  Fly   392 ISTWRDTRTIQLNQNRRYTTKSFSKG------GGSPRA-ESMR-PLTSYYGRGKRESCVSSATTT 448
            ||.:...|.......||.:.  ||.|      ..:|.| |..| |.|:........|..::|:..
Mosquito   442 ISVYLSLRGHHDWAIRRQSL--FSAGYPTAPINETPHAGEPQRTPNTNNNNNNNNNSSRNAASNN 504

  Fly   449 TLVGQHAPLSLHRGSNNALHTMPTLAANAMSSGS 482
            .|.|        ..|:|..||    |...|:.|:
Mosquito   505 LLAG--------AASSNNHHT----ANGGMAGGN 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	27/69 (39%)
		7tmB1_DH_R	126..394	CDD:320391	103/288 (36%)
		TM helix 1	128..153	CDD:320391	8/24 (33%)
		TM helix 2	162..184	CDD:320391	5/21 (24%)
		TM helix 3	197..224	CDD:320391	10/26 (38%)
		TM helix 4	236..256	CDD:320391	9/21 (43%)
		TM helix 5	279..308	CDD:320391	11/28 (39%)
		TM helix 6	322..349	CDD:320391	13/28 (46%)
		TM helix 7	356..381	CDD:320391	9/24 (38%)
Pdfr	XP_061496572.1	None