Protein Alignment Dh44-R1 and Calcr

DIOPT Version :10

• Sequence 1: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: NP_446268.2
• Gene: Calcr / 116506
• RGDID: 621001
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 437
• Identity: 122/437 - (27%)
• Similarity: 207/437 - (47%)
• Gaps: 82/437 - (18%)

  Fly    46 YGNDSGHCLTQFDSILCWPRTARGTLAVLQCMDELQGIHYDSSKNATRFCHANGTW-------EK 103
            |..:..:|...:|..:||..|..|.::...|.|...  .:|.::..:::|..||.|       ..
  Rat    82 YEGEGPYCNRTWDGWMCWDDTPAGVMSYQHCPDYFP--DFDPTEKVSKYCDENGEWFRHPDSNRT 144

  Fly   104 YTNYDACAHLPAPESVPEFEVIVELPTIIYY---IGYTLSLVSLSLALIVFAYFKELRCLRNTIH 165
            ::||..| :...|:.:..       ..::||   :|:::|:.:|..::.:|.:||.|.|.|.|:|
  Rat   145 WSNYTLC-NAFTPDKLHN-------AYVLYYLALVGHSMSIAALIASMGIFLFFKNLSCQRVTLH 201

  Fly   166 ANLFFTYIMSALF---------------------------------WILLLSVQISIRSG----- 192
            .|:|.|||::::.                                 |.|...:.:|...|
  Rat   202 KNMFLTYILNSIIIIIHLVEVVPNGDLVRRDPMHIFHHNTYMWTMQWELSPPLPLSAHEGKMDPH 266

  Fly   193 ---VGSCIALITLFHFFTLT-NFFWMLVEGLYLYMLVVKTFSGDNLRFNIYASIGWGGPALFVVT 253
               |.|| .::..||.:.:. |:||||.||:||:.|:|.....::.|...|..:|||.|.:..:.
  Rat   267 DSEVISC-KILHFFHQYMMACNYFWMLCEGIYLHTLIVMAVFTEDQRLRWYYLLGWGFPIVPTII 330

  Fly   254 WAVAKSLTVTYSTPEKYEINCPWMQ-ETHVDWIYQGPVCAVLIINLTFLLRIMWVLITKLRSANT 317
            .|:.:::        .|..|| |:. |||:.:|..|||.|.|::|..|||.|:.||:||:|..:.
  Rat   331 HAITRAV--------YYNDNC-WLSTETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRQTHE 386

  Fly   318 VETRQYRKAAKALLVLIPLFGITYLVVLAGPSESGLMGHMFAVLRAVLLSTQGFSVSLFYCFLNS 382
            .|...|.||.||.:||:||.||.::|....||.. ::|.::..|...|:..|||.|:..|||.|.
  Rat   387 AEAYMYLKAVKATMVLVPLLGIQFVVFPWRPSNK-VLGKIYDYLMHSLIHFQGFFVATIYCFCNH 450

  Fly   383 EVRNALRHHISTWRDTRTIQLNQNRRYTTK--------SFSKGGGSP 421
            ||:..|:...:.::...:.:..:.||.|.:        :|::.||.|
  Rat   451 EVQVTLKRQWAQFKIQWSHRWGRRRRPTNRVVSAPRAVAFAEPGGLP 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	16/66 (24%)
		7tmB1_DH_R	126..394	CDD:320391	97/313 (31%)
		TM helix 1	128..153	CDD:320391	6/27 (22%)
		TM helix 2	162..184	CDD:320391	9/54 (17%)
		TM helix 3	197..224	CDD:320391	11/27 (41%)
		TM helix 4	236..256	CDD:320391	5/19 (26%)
		TM helix 5	279..308	CDD:320391	14/28 (50%)
		TM helix 6	322..349	CDD:320391	12/26 (46%)
		TM helix 7	356..381	CDD:320391	9/24 (38%)
Calcr	NP_446268.2	HRM	86..154	CDD:397086	16/70 (23%)
		7tmB1_calcitonin_R	162..472	CDD:341343	97/320 (30%)
		TM helix 1	164..189	CDD:341343	6/24 (25%)
		TM helix 2	198..220	CDD:341343	7/21 (33%)
		TM helix 3	274..301	CDD:341343	11/26 (42%)
		TM helix 4	313..333	CDD:341343	5/19 (26%)
		TM helix 5	348..377	CDD:341343	14/28 (50%)
		TM helix 6	391..418	CDD:341343	12/26 (46%)
		TM helix 7	424..449	CDD:341343	9/24 (38%)