Protein Alignment Dh44-R1 and glp1r

DIOPT Version :10

• Sequence 1: NP_610960.1
• Gene: Dh44-R1 / 36601
• FlyBaseID: FBgn0033932
• Length: 504
• Species: Drosophila melanogaster
• Sequence 2: XP_031758064.1
• Gene: glp1r / 101734463
• XenbaseID: XB-GENE-940017
• Length: 440
• Species: Xenopus tropicalis
• Alignment Length: 381
• Identity: 117/381 - (30%)
• Similarity: 177/381 - (46%)
• Gaps: 60/381 - (15%)

  Fly    53 CLTQFDSILCWPRTARGTLAVLQCMDELQGIHYDSSKNATRFCHANGTW-------EKYTNYDAC 110
            |...||...|||....||...:.|...|...|..:.....|:|...|.|       ..:.|...|
 Frog    51 CNRTFDDYACWPDALPGTYVNVTCPWYLPWSHKVTHGRVFRYCTPEGNWLLKENSSAPWRNLSEC 115

  Fly   111 AHLPAPESVPEFEVIVELPTIIYYIGYTLSLVSLSLALIVFAYFKELRCLRNTIHANLFFTYIMS 175
            .....  .||..|.:..| ::||.|||:||..:|.:|.|:...|:.|.|.||.||.|||.::|:.
 Frog   116 EDRSL--KVPPEEQLSSL-SVIYTIGYSLSFSALIIATIILVRFRHLHCTRNYIHLNLFTSFILR 177

  Fly   176 ALF--------------------WILLLSVQISIRSGVGSCIALITLFHFFTLTNFFWMLVEGLY 220
            |:.                    |..|:|.|.|:     ||..:..:..:....|::|:||||:|
 Frog   178 AISVFIKDSVLKWMYNLAMNDNQWEGLVSYQESL-----SCRLVFAMMQYCVAANYYWLLVEGIY 237

  Fly   221 LY-MLVVKTFSGDNLRFNIYASIGWGGPALFVVTWAVAKSLTVTYSTPEKYEINCPWMQETHVD- 283
            |: :||:..||...| |.:|..||||.|.||||.||:.|.|         ||.|..|.:..:::
 Frog   238 LHTLLVLSVFSEQRL-FRLYLCIGWGVPVLFVVPWAIVKYL---------YEDNGCWTRNYNMNF 292

  Fly   284 W-IYQGPVCAVLIINLTFLLRIMWVLITKLRSANTVETRQYRKAAKALLVLIPLFGITYLVVLAG 347
            | |.:.|:...:.:|....:|::.::|:||::.....|....:.||:.|.||||.| |:.::.|.
 Frog   293 WLIIRLPILMAIGVNFVIFIRVICIIISKLQANLMCRTDTKCRLAKSTLTLIPLLG-THEIIFAF 356

  Fly   348 PSESGLMGHMFAVLRAVLL-------STQGFSVSLFYCFLNSEVRNALRHHISTWR 396
            .::.    |....||.:.|       |.||..|::.|||:|:||:...:.....||
 Frog   357 ITDE----HAKGALRYIKLFFELSFSSFQGLMVAILYCFINNEVQTEFQRRWERWR 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dh44-R1	NP_610960.1	HRM	52..112	CDD:397086	17/65 (26%)
		7tmB1_DH_R	126..394	CDD:320391	95/297 (32%)
		TM helix 1	128..153	CDD:320391	11/24 (46%)
		TM helix 2	162..184	CDD:320391	10/41 (24%)
		TM helix 3	197..224	CDD:320391	8/27 (30%)
		TM helix 4	236..256	CDD:320391	12/19 (63%)
		TM helix 5	279..308	CDD:320391	5/30 (17%)
		TM helix 6	322..349	CDD:320391	10/26 (38%)
		TM helix 7	356..381	CDD:320391	11/31 (35%)
glp1r	XP_031758064.1	HRM	48..116	CDD:397086	16/64 (25%)
		7tmB1_GLP1R	128..406	CDD:341342	95/298 (32%)
		TM helix 1	130..155	CDD:341342	11/25 (44%)
		TM helix 2	164..186	CDD:341342	8/21 (38%)
		TM helix 3	214..241	CDD:341342	8/26 (31%)
		TM helix 4	253..273	CDD:341342	12/19 (63%)
		TM helix 5	289..318	CDD:341342	5/28 (18%)
		TM helix 6	332..359	CDD:341342	10/27 (37%)
		TM helix 7	368..393	CDD:341342	8/24 (33%)