Protein Alignment Arc1 and ARC

DIOPT Version :9

• Sequence 1: NP_610955.1
• Gene: Arc1 / 36595
• FlyBaseID: FBgn0033926
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_056008.1
• Gene: ARC / 23237
• HGNCID: 648
• Length: 396
• Species: Homo sapiens
• Alignment Length: 223
• Identity: 55/223 - (24%)
• Similarity: 83/223 - (37%)
• Gaps: 32/223 - (14%)

  Fly    26 AAGSAAAAGGADASR---------GKGNFSACTHSFGGTRDHDVVEEFIGNIETYKDVEGISDEN 81
            |||.......|:|.:         |:.:....|..|...|      ||:.::|.|....|.|:|.
Human   179 AAGELPGQEPAEAQQYQPWVPGEDGQPSPGVDTQIFEDPR------EFLSHLEEYLRQVGGSEEY 237

  Fly    82 ALKGISLLFYGMASTWWQGVRKEATTWKEAIALIREHFSPTKPAYQIYMEFFQNKQDDHDPIDTF 146
            .|..|.....|.|..||:..:.....|.|......::...|.....|..| ....|...:|:|.|
Human   238 WLSQIQNHMNGPAKKWWEFKQGSVKNWVEFKKEFLQYSEGTLSREAIQRE-LDLPQKQGEPLDQF 301

  Fly   147 VIQKRALLAQLPSGRHDEETELDLLFGLLNIKYRKHISRHSVHTFKDLLEQGRIIE--------- 202
            :.:||.|...|.... |||..:..:.|.|..|.::.:......|.:.|:::|..::
Human   302 LWRKRDLYQTLYVDA-DEEEIIQYVVGTLQPKLKRFLRHPLPKTLEQLIQRGMEVQDDLEQAAEP 365

  Fly   203 ---HNNQEDE-EQLATAKNTR--GSKRT 224
               |...||| |.|..|.|:.  .|.||
Human   366 AGPHLPVEDEAETLTPAPNSESVASDRT 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arc1	NP_610955.1	None
ARC	NP_056008.1	Interaction with SH3GL1 or SH3GL3. /evidence=ECO:0000250|UniProtKB:Q63053	89..100
		Interaction with DNM2. /evidence=ECO:0000250|UniProtKB:Q63053	195..214		2/18 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	356..396		11/38 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910