DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tej and tdrd6

DIOPT Version :9

Sequence 1:	NP_610950.2	Gene:	tej / 36590	FlyBaseID:	FBgn0033921	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	XP_694024.6	Gene:	tdrd6 / 565665	ZFINID:	ZDB-GENE-041001-210	Length:	2117	Species:	Danio rerio

Alignment Length:	436	Identity:	90/436 - (20%)
Similarity:	147/436 - (33%)	Gaps:	117/436 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 NANSKSLKVNDWS--QKDRKQEPSKERNNQKYPKITTENKQEKETEE----LAQAFENLSVDVAP 242
            |.|...:.|..|.  .:|||....:.:...:||:   |...|.:...    |.|.:|..
Zfish    22 NLNPSCVLVEFWGNFDEDRKFAYQQLKKEIQYPR---ECFSESDGNPGDLCLVQVYETW------ 77

  Fly   243 TDHQEKLKCEIYEDNEDEFVRDPFIYGEVKEKEDEAVVLA------FDAVSEDGFDLLSMTTTQQ 301
                  .:..|...:.||:  ..|:..|.:........||      |....|..|.:|:
Zfish    78 ------YRARIVSRDSDEY--SVFLIDEGRTLRAAVNTLAWGKSDFFYLPPEVEFCILA------ 128

  Fly   302 NAVKPLDPPED----CLHYASSDDGEDENA-IPAYAVDHRVLDVDYP------------------ 343
            ||: ||.|..:    .|.:..:..|...|| :....|.||...:|.|
Zfish   129 NAL-PLSPENNWSSMALEFMKTFCGRRVNATVQDVLVAHRTFLLDIPCLSRQMFEMGFAKKLYSD 192

  Fly   344 -------RDAVRSAFTLPARDIES-------IIELQQRIR--------------VQLVSLVNPHN 380
                   |....|..|...:.|.|       |||.:::.:              |.:..:.:|..
Zfish   193 QFMEFVVRSLQASTGTSDLKRISSIRTKPVEIIEQKEKQQAYMFPELQTDTVETVVITEVTSPFR 257

  Fly   381 F--NFWIYNDDFKDYEAQFANMQTFYES------SESKNYTMPLFLITTDHLCVVRCTSG-WERA 436
            .  ...:::.:.|....|...   :||.      :.::|...|         |..|.:.| |.|:
Zfish   258 IFCQLKVFSQELKKLTEQITQ---YYEGRVGSYFARAENLGSP---------CASRGSDGKWYRS 310

  Fly   437 KVLGYRSSNNKMTIEVELVDIGDIIRVSQQNVKFLIKPFALLPRQCLAGRLAFITQCKSPNWTAE 501
            .:....|:||  .:||..||.|....|..:|||.|...|..:|.......|..|.. |...|||.
Zfish   311 VLQQVMSANN--VVEVLHVDYGKKQFVQVENVKPLASEFFRMPVVTYVCSLHGIVD-KGVGWTAS 372

  Fly   502 VVNFFHDMILLRLLYAK--VEAIKNNTAYLVLVDTESQGHTVNLNR 545
            .:::...::|.|.:.||  .:::.....|:.|...|:    .|:|:
Zfish   373 QIDYLKSLLLNRTVIAKFQYQSLSEGVHYVTLYGEEN----TNINK 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tej	NP_610950.2	LOTUS_TDRD_OSKAR	7..93	CDD:193586
tej	NP_610950.2	TUDOR	379..488	CDD:278965	26/117 (22%)
tdrd6	XP_694024.6	Tudor_SF	6..132	CDD:413384	27/133 (20%)
		Tudor_TDRD6_rpt2	233..361	CDD:410492	29/141 (21%)
		Tudor_SF	482..613	CDD:413384
		Tudor_SF	705..828	CDD:413384
		Tudor_SF	917..1042	CDD:413384
		Tudor_SF	1238..1349	CDD:413384
		Tudor_SF	1440..1579	CDD:413384
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810