Protein Alignment tej and TDRD1

DIOPT Version :9

• Sequence 1: NP_610950.2
• Gene: tej / 36590
• FlyBaseID: FBgn0033921
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001372292.1
• Gene: TDRD1 / 56165
• HGNCID: 11712
• Length: 1189
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 92/501 - (18%)
• Similarity: 177/501 - (35%)
• Gaps: 109/501 - (21%)

  Fly    95 SKNRGSHKPKYCYASEPSNLVFINESVSKMKNRKAPFPTYQVPRNLKLPVSYPNYNRLLYPVHTP 159
            |:|.....|  |..:||.|.       .|.:|:..|..:.:.|..|.   ::||: ||....:..
Human    11 SRNNLEAPP--CKMTEPFNF-------EKNENKLPPHESLRSPGTLP---NHPNF-RLKSSENGN 62

  Fly   160 HIDQMISTGQQQSTLRTQRP-SFPCNANSKSLKVNDWSQKDRKQEPSKERNNQKYPKITTENKQE 223
            ..:..:...|.:..|.:|.. |...|.|..:.:|.. |:.|||:.|:   .|...|.....|...
Human    63 KKNNFLLCEQTKQYLASQEDNSVSSNPNGINGEVVG-SKGDRKKLPA---GNSVSPPSAESNSPP 123

  Fly   224 KE-------------TEELAQAFEN--------LSVDVAP-----TDHQEKLKCEIYEDNEDEFV 262
            ||             :::|.:..||        |...:.|     |.|    :|.
Human   124 KEVNIKPGNNVRPAKSKKLNKLVENSLSISNPGLFTSLGPPLRSTTCH----RCG---------- 174

  Fly   263 RDPFIYGEVKEKEDEAVVLAFDAVSEDGFDLLSMTTTQQNAVKPLDPPEDCLHYASSDDGEDENA 327
                ::|.::..:.:.......|.....:...|:      ..:|:.|....|...||.:.:|
Human   175 ----LFGSLRCSQCKQTYYCSTACQRRDWSAHSI------VCRPVQPNFHKLENKSSIETKD--- 226

  Fly   328 IPAYAVDHRVLDVDYPRD------------AVRSAFTLPARDIESI-IELQQRIRVQLVSLVNPH 379
                      ::|:...|            |.|..|:    |:.|: ::....|:..:....:|.
Human   227 ----------VEVNNKSDCPLGVTKEIAIWAERIMFS----DLRSLQLKKTMEIKGTVTEFKHPG 277

  Fly   380 NFNFWIYNDDFKDYEAQF-ANMQTFYESSESKNYTMPLFLITTDHLCVVRCT--SGWERAKVLGY 441
            :|...:|:.:..:|..|. |:::..|.:...|:| :|:    ...:|:.:.|  ..|.||.:...
Human   278 DFYVQLYSSEVLEYMNQLSASLKETYANVHEKDY-IPV----KGEVCIAKYTVDQTWNRAIIQNV 337

  Fly   442 RSSNNKMTIEVELVDIGDIIRVSQQNVKFLIKPFALLPRQCLAGRLAFITQCKSPNWTAEVVNFF 506
            .....|  ..|..:|.|:...:....:..|.:...|.|...:...:|.:...:. ||:::.:...
Human   338 DVQQKK--AHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVIPAEG-NWSSDCIKAT 399

  Fly   507 HDMILLRLLYAKVEAIKNNTAYLVLVDTESQGHTVNLNRSLIETGW 552
            ..:::.:....|:..|.........|:.|.......|:..|||.|:
Human   400 KPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLDHVLIEMGY 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tej	NP_610950.2	LOTUS_TDRD_OSKAR	7..93	CDD:193586
		TUDOR	379..488	CDD:278965	21/111 (19%)
TDRD1	NP_001372292.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..66		16/67 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	79..138		15/62 (24%)
		zf-MYND	170..206	CDD:396356	5/59 (8%)
		Tudor_TDRD1_rpt1	268..396	CDD:410479	25/135 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	450..469
		Tudor_TDRD1_rpt2	517..598	CDD:410480
		TUDOR	715..832	CDD:395449
		Tudor_TDRD1_rpt4	944..1059	CDD:410482

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810