DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tej and tapas

DIOPT Version :9

Sequence 1:	NP_610950.2	Gene:	tej / 36590	FlyBaseID:	FBgn0033921	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_611475.3	Gene:	tapas / 37304	FlyBaseID:	FBgn0027529	Length:	1222	Species:	Drosophila melanogaster

Alignment Length:	808	Identity:	150/808 - (18%)
Similarity:	248/808 - (30%)	Gaps:	338/808 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LSLVKKVVHSLVVSSPGKLTVEQLMRDYRSEEGCTLPYSKLGFKDAESFLRSIPDTVTVTGH--G 69
            |..|.|||.:|:.|:...:|:..::.||...||..:|:.:||:.:.:..|:   |:.....|  |
  Fly     7 LEYVAKVVRALITSAKPPVTLRSIVADYMEIEGEPIPFRRLGYSNDQELLK---DSNQFNFHQSG 68

  Fly    70 QMAWITAVATAKSAHIQKLVRCQKKSKNRGSHKPKYCYASEPSNLVFINESVSKMKNRKAPFPTY 134
            ...:|||...|.:.||.::||.||.||                     :.|:||      |.|..
  Fly    69 NQVFITAKYNANTEHIVRMVRQQKTSK---------------------STSLSK------PTPIA 106

  Fly   135 QVPRNLKLPVS--------YPNYNRLLYPVHTPHID---------QMISTGQQQST-LRTQR--P 179
            |.|:    |::        |....|...|.|.|..:         |.|:..:|..| :.||.  .
  Fly   107 QKPK----PIAQKHTHGNKYHYQQRNKQPNHQPDQEIGRAAKCENQAIAEHKQDLTGIITQELFE 167

  Fly   180 SF-----PCNANSKSLKVNDWSQKDRKQEPSKERN---NQKYPKITTENKQEKETEELAQAFENL 236
            ||     |.:.|.:....|......||:|..||.:   .|...::..|.::||||.:.| ..|.:
  Fly   168 SFNNIQGPFSENLQVFNKNPEYITRRKKELKKEDDLDRGQITKEVAREKQKEKETRDRA-VTETI 231

  Fly   237 SVDV----AP-------------------TDHQEKLKC--------------EIYEDNEDEF--V 262
            .|.:    ||                   .|.:..|:.              .:|...|..|  .
  Fly   232 FVTIENKKAPVMNGHGPRHVKVANGQDKHNDGKPPLRAILGNSASQRQQDTSTVYHSPESSFKRP 296

  Fly   263 RDPFIYGEVKEK--------------EDEAVVLAFDAVSEDGFDLLSMTTTQQNA---------- 303
            |.|.:.....::              :.:|...|...::.......:.|||...|
  Fly   297 RHPRVMYPGHQRTTGVSVNHRLKVTPQSDAPTPAVAPITPPASPEYAQTTTAAKATYKEDIHGGQ 361

  Fly   304 -----------VK-------PLDPPEDCLHYASSDDGEDENAIPAYAVDHRVLDV---------- 340
                       ||       .|||......|.:::|.|.    |||.:.:::.::
  Fly   362 GETGNVVTNPKVKVPLKFDPSLDPVSTLNFYCAANDFEK----PAYNIFNKLRNLHCSVQIAGDV 422

  Fly   341 --DYPRD--------------AVR-----------SAFT-------------------------- 352
              .||::              |::           ||.|
  Fly   423 YSSYPQEFTDKETAYQRTAQIAIQRIMHAQSHQKLSACTFSDVEFIDGLYKELLKHPHGILGHKL 487

  Fly   353 -----------LPARDIESIIELQQRIRVQ--------------------------LVSLVNP-- 378
                       ||:...:.|:: ..:|||:                          |..:|.|
  Fly   488 EDWYGSTFRQHLPSHWYDLIVK-SNKIRVEHGIDPRIILFANDPGSSEPDRTSITTLPQMVLPWQ 551

  Fly   379 ------HNFNFWI-YNDDFKDYEA----QFANMQTF------------YESSESKNYTMPLFLIT 420
                  |::|.:| :.|..|...|    |.||.:..            :....||.|...::|
  Fly   552 SSEGGSHDWNMFISFCDSTKIVWARMIDQIANFEELTKHIGRQMESPHFRQKVSKPYAQEVYL-- 614

  Fly   421 TDHLCVVRCTSGWERAKVLGY----RSSNNKMTIEVELVDIGDIIRVSQQNVKFLIKPFALLPRQ 481
                  |....||.|.:.:..    ||.      ....:|.||:.....:::......|..||.|
  Fly   615 ------VEMPDGWNRVRAISVDEETRSG------RYHFIDFGDVAMFHSEDLFHCPPQFLALPAQ 667

  Fly   482 CLAGRLAFITQCKSPNWTAEVVNFFHDMILLRLLYAKVEAIKNNTAYLVLVDTESQGHTVNLN-- 544
            .:         |.|                   :|| ::..:::...|.::..|..|.||..:
  Fly   668 AV---------CLS-------------------MYA-LDKFEDHPHALQVLTKELDGQTVVAHVL 703

  Fly   545 -------------RSLIETGWVRRCTSA 559
                         :.::|.|..|.|..|
  Fly   704 TTEKQFLELGGSAQGVVENGKRRACLVA 731

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tej	NP_610950.2	LOTUS_TDRD_OSKAR	7..93	CDD:193586	27/87 (31%)
tej	NP_610950.2	TUDOR	379..488	CDD:278965	26/129 (20%)
tapas	NP_611475.3	LOTUS_TDRD_OSKAR	7..92	CDD:193586	27/87 (31%)
		TUDOR	563..673	CDD:278965	26/151 (17%)
		TUDOR	766..896	CDD:278965
		TUDOR	1032..1151	CDD:278965
		TUDOR	1087..1131	CDD:119391
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1525
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900