Protein Alignment tej and Tdrd5

DIOPT Version :10

• Sequence 1: NP_610950.2
• Gene: tej / 36590
• FlyBaseID: FBgn0033921
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001128213.1
• Gene: Tdrd5 / 214575
• MGIID: 2684949
• Length: 1040
• Species: Mus musculus
• Alignment Length: 690
• Identity: 146/690 - (21%)
• Similarity: 244/690 - (35%)
• Gaps: 192/690 - (27%)

  Fly    10 VKKVVHSLVVSSPGKLTVEQLMRDYRSEEGCTLPYSKLGFKDAESFLRSIPDTVTVT--GHGQMA 72
            ::|.:.||::|:...||.:||.::|....|..||...||::.....:..:||.|:|.  |.|.:.
Mouse    11 LRKEIRSLLISTKDGLTPQQLEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVSVCPGGDGTVI 75

  Fly    73 WITAVATAKSAHIQKLVRCQKKSKNRGSHK---------PKYCYASEP----------------- 111
             :.|:....:..|..||     :|.|.|||         |..|....|
Mouse    76 -LKAIPDESTKGIASLV-----AKQRRSHKVRNSMPKGRPSICSGRVPYRGRVPPILPAVVKSEL 134

  Fly   112 ------------------------------------------------------SNLVFINESVS 122
                                                                  .:|:.:.:|||
Mouse   135 KDLLALSPVLLSDFEKAFARRFGRSFQYMQYGFLSMFEVLNAASDVISVEQTRAGSLLTLKKSVS 199

  Fly   123 KMKNRKAPF-PTYQVPRNLKLPVSYPNYNRLLYPVHTPHIDQMISTGQ--QQSTLRTQRPSFPCN 184
            :.|.|..|. ..:..|..:|...||...    :||...|..|.||..:  :|.....:.|:|
Mouse   200 EDKQRGWPAGKVFTQPFRMKQQGSYSTG----FPVMKAHFSQPISNMEPPKQVLSMAKTPTF--- 257

  Fly   185 ANS-KSLKVNDWSQKDRKQ----------------EPSKERNNQ----KYP------KITTE--- 219
             || ::.::|...:.::.:                :|..:|..|    |:|      |:..|
Mouse   258 -NSVEASRLNHTEKLNQLESTFKSVIAQIGPGGTVDPELKRKIQFVVSKFPQGLFISKLLGEFEL 321

  Fly   220 -NKQEKETEELAQAFENLSVDVAPTDHQEKLKCEIYEDNEDEFVRD----PFIYGEVKEKEDEAV 279
             .|::...::|  .|.|::..|...  .:.|:.|..|:.:|..|.|    |...|........:.
Mouse   322 TFKEQLSPKQL--GFLNVTELVGAL--SDILRVEFSEERQDLLVFDADLKPLPSGGPLSSVRNSC 382

  Fly   280 VLAFDAVSEDGFDLLSMTTTQQNAVKPLDPPEDCLHYASSDDGEDENAI---PAYAVDHRVLDV- 340
            ::..|..:|......|::....:.|.......||   ...:..|.|..|   |...|....|.|
Mouse   383 LVQPDKKTEANPWTSSLSRNSLSTVAVKKTTWDC---PLKNQKEPEQKIYKKPNLVVKPLQLQVE 444

  Fly   341 -------------DYPRDAVRS--AFTLPARDIESIIELQQRIRVQLVSLVNPHNFNFWIYNDDF 390
                         |.|.||||:  ...||..|..::      :.|.:..:::|..|...||:.|.
Mouse   445 TNKPQLSLSVANHDIPPDAVRAKKLCRLPPLDTSTL------VGVFVEYIISPSQFYIRIYSRDS 503

  Fly   391 KD-YEAQFANMQTFYESS-ESKNYTMPLFLITTDHLCVVRCTSG--WERA---KVLGYRSSNNKM 448
            .: .|.....|:..|.:. .|..|.||.:.|...|||.|:.:..  |.|.   ::||      |.
Mouse   504 SELLEDMMIEMRRCYSNQLVSDRYIMPEYFIQPGHLCCVKISEDKWWYRVIIHRILG------KK 562

  Fly   449 TIEVELVDIGDIIRVSQQNVKFLIKPFALLPRQCLAGRLAFITQCKSPNWTAEVVNFFHDMILLR 513
            .:||...|.|:|..|.:.:::||...:..||.|.:...||::...:. :|||..:..|..:..|:
Mouse   563 EVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPAEE-HWTARAILHFQKLCGLK 626

  Fly   514 LLYAKVEAIKNNTAYLVLVDTES------------QGHTV 541
            .|...|:...:....:.|.||.|            :||.:
Mouse   627 PLVGVVDEYIDGILNIFLCDTSSNEDVYFHHVLRTEGHAI 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tej	NP_610950.2	LOTUS_TDRD_OSKAR	7..93	CDD:193586	24/84 (29%)
		TUDOR	379..488	CDD:425754	32/115 (28%)
Tdrd5	NP_001128213.1	LOTUS_1_TDRD5	4..98	CDD:193599	26/92 (28%)
		LOTUS_2_TDRD5	127..196	CDD:193589	1/68 (1%)
		LOTUS_3_TDRD5	292..365	CDD:193590	18/76 (24%)
		Tudor_TDRD5	484..601	CDD:410490	33/122 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	857..891
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	912..975