DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ih and CNGC4

DIOPT Version :9

Sequence 1:	NP_001033948.1	Gene:	Ih / 36589	FlyBaseID:	FBgn0263397	Length:	1327	Species:	Drosophila melanogaster
Sequence 2:	NP_001332114.1	Gene:	CNGC4 / 835513	AraportID:	AT5G54250	Length:	694	Species:	Arabidopsis thaliana

Alignment Length:	569	Identity:	108/569 - (18%)
Similarity:	206/569 - (36%)	Gaps:	133/569 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   717 DNRLAMKLFGSRKALVKERIRQKTSGHW-----VIHPCSSFRFYWDLCMLLLLVANLIILPVAIS 776
            |.|:.:...|.|..       ...:..|     ::.|.|.:...|:...||:....|.:.|:.:.
plant    53 DPRIGLTCGGRRNG-------SSNNNKWMMLGRILDPRSKWVREWNKVFLLVCATGLFVDPLFLY 110

  Fly   777 FFNDD------LSTRWI-----AFNCLSDTIFLIDIVVNFRT--------GIMQQD-NAEQVILD 821
            ..:..      |...|:     |...::|.:.|.:|.:.|:.        |....| |.......
plant   111 TLSVSDTCMCLLVDGWLALTVTALRSMTDLLHLWNIWIQFKIARRWPYPGGDSDGDTNKGGGTRG 175

  Fly   822 PKLIAKHYL-RTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLV 885
            ...:|..|: :..||.||...:||..:.|              :.::.:     :|:...:..:|
plant   176 STRVAPPYVKKNGFFFDLFVILPLPQVVL--------------WVVIPS-----LLKRGSVTLVV 221

  Fly   886 RLLRLSRLVRYVSQWEEVY-ILQNLQKKSADRRGRMNRKDKDGLTKSNLILK------FLNMASV 943
            .:|.::.|.:|:   .::| .:::|::.:               |.|..|..      .|||.:.
plant   222 SVLLVTFLFQYL---PKIYHSIRHLRRNA---------------TLSGYIFGTVWWGIALNMIAY 268

  Fly   944 FMRIFNLICMMLLIG-------------HWSGC----LQFLVPMLQGF-------PSNSWVSIN- 983
            |:..........|:|             :..||    |....|:..|.       ...:|...:
plant   269 FVAAHAAGACWYLLGVQRSAKCLKEQCENTIGCDLRMLSCKEPVYYGTTVMVLDRARLAWAQNHQ 333

  Fly   984 ------ELQESYWLEQYSWALFKAMSH--------------MLCIGYGRFPPQSLTDMW----LT 1024
                  ::..:|....|.|.:....|.              |....:|..  :|.|: |    ..
plant   334 ARSVCLDINTNYTYGAYQWTIQLVSSESRLEKILFPIFWGLMTLSTFGNL--ESTTE-WSEVVFN 395

  Fly  1025 MLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQ 1089
            ::.:.||.....:.:|:....:.:..|.::....|::.:|.:|..|.||...|||:..|...|:.
plant   396 IIVLTSGLLLVTMLIGNIKVFLHATTSKKQAMHLKMRNIEWWMKKRHLPIGFRQRVRNYERQRWA 460

  Fly  1090 G-KFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIK 1153
            . :..||..::..|.|.||.|:..:.|..||..||.|.:.|...:.::..::|..:|..|:.|.|
plant   461 AMRGVDECEMVQNLPEGLRRDIKYHLCLDLVRQVPLFQHMDDLVLENICDRVKSLIFTKGETIQK 525

  Fly  1154 EGTIGTKMYFIQEGVVDI--VMANG-EVATSLSDGSYFGEICLLTNARR 1199
            ||....:|.|:..|.:..  ::.:| :....|..|::.|:..|....||
plant   526 EGDAVQRMLFVVRGHLQSSQLLRDGVKSCCMLGPGNFSGDELLSWCLRR 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ih	NP_001033948.1	Ion_trans_N	709..751	CDD:285597	6/38 (16%)
		Ion_trans	771..1054	CDD:278921	55/359 (15%)
		Crp	1118..>1241	CDD:223736	23/85 (27%)
		CAP_ED	1124..1233	CDD:237999	19/79 (24%)
CNGC4	NP_001332114.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0498
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820