DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ih and HCN2

DIOPT Version :10

Sequence 1:	NP_001033948.1	Gene:	Ih / 36589	FlyBaseID:	FBgn0263397	Length:	1327	Species:	Drosophila melanogaster
Sequence 2:	NP_001185.3	Gene:	HCN2 / 610	HGNCID:	4846	Length:	889	Species:	Homo sapiens

Alignment Length:	28	Identity:	6/28 - (21%)
Similarity:	12/28 - (42%)	Gaps:	0/28 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 HTAVGDYEPETSITVFRNASPHPWSKYR 190
            |..:..|||:..::.........|.:|:
Human     4 HQPLQYYEPQLCLSCLTGIYGCRWKRYQ 31

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ih	NP_001033948.1	Ion_trans_N	709..751	CDD:400630
Ih	NP_001033948.1	PLN03192	741..>1214	CDD:215625
HCN2	NP_001185.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..159		6/28 (21%)
		PBP1	<57..185	CDD:444064
		PLN03192	150..>688	CDD:215625
		Involved in subunit assembly. /evidence=ECO:0000250	158..209
		CAP_ED	544..652	CDD:237999
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	754..889
Blue background indicates that the domain is not in the aligned region.

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