Protein Alignment Ih and LOC4576205

DIOPT Version :10

• Sequence 1: NP_001033948.1
• Gene: Ih / 36589
• FlyBaseID: FBgn0263397
• Length: 1327
• Species: Drosophila melanogaster
• Sequence 2: XP_061498773.1
• Gene: LOC4576205 / 4576205
• VectorBaseID: AGAMI1_000492
• Length: 927
• Species: Anopheles gambiae
• Alignment Length: 889
• Identity: 211/889 - (23%)
• Similarity: 355/889 - (39%)
• Gaps: 236/889 - (26%)

  Fly   421 KISSSASGSKNCNLLSASSNS-CHKLNAHAQGS-GAGSGSGSGSGSGPPGHSHYAAASPKSSVSS 483
            |.|...:|:.:..|:||:|.| .|:|:..|..| ||.|           ||..|.:.       |
Mosquito    15 KESHGTAGTSSTRLVSANSTSPGHELDEIAVVSVGAES-----------GHVSYGSL-------S 61

  Fly   484 NGHLN--KYCLTDLTRRKAEFNRQLSAPTDYTHHSSS-NGSQQEGSSEANEGHEPVGESTITVAS 545
            .||.|  :|...|.....:..:.:||     .|||.| ||:.......|....|.||....|:.|
Mosquito    62 LGHTNGPRYIPDDDDGNASFDSTKLS-----RHHSHSLNGTDAAIMHLAPPPLEAVGSDFNTIQS 121

  Fly   546 AGVSYPHPYSYPYHYAHHASSATAPA--------------NLKASLQLHSFGSHHPC-------- 588
            :.             .|:.:|.:..:              .|..|:....|.|....
Mosquito   122 SA-------------DHNRNSVSRQSLMDIVSSKLGMSGPQLGQSISQQGFFSSRDSLSASGTSR 173

  Fly   589 PYPARPTSTSCTNSFNRRHIRRHKGK--------LGDRLLSGDSEESVRC-SYCSVLNVNDNDLR 644
            |..:..::|:.....:|:..:|.:.|        ||....:|..|.:... ..|:....:.|.|
Mosquito   174 PLHSHVSATTSEMDLSRKDRKRERSKLKAADPPLLGSWSRTGPRESNANAMGPCATTRASTNHL- 237

  Fly   645 ISFENTCTDSLVTAFDDEALLICDQGTEMVHFDDVSLYGTPKEEPMPNIPIVSEKVSANFLKSQL 709
                              |...|..|:
Mosquito   238 ------------------AAAPCGTGS-------------------------------------- 246

  Fly   710 QSWFQPTDNRLAMKLFGSRKALVKERIRQKTSG-HW--VIHPCSSFRFYWDLCMLLLLVAN--LI 769
                  |.|.....:||.|...  ....:|::| .|  |..|.....:||.:.:.:..:.|  :|
Mosquito   247 ------TCNGADRYIFGRRSGC--STTSRKSNGRRWSFVFDPAGRLCYYWSMVVSMAFLYNFWVI 303

  Fly   770 ILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLR-TW 833
            |...|....|.:....|...:..||.::|:||:.:||||.: :|...|.  |...:.:||:. |.
Mosquito   304 IYRFAFQEINGESIVLWFCLDYFSDFLYLVDILFHFRTGYL-EDGVLQT--DSTKLRQHYMNSTT 365

  Fly   834 FFLDLISSIPLDYIFLI--FNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRY 896
            |::|.:..:|||:::|.  ||.|::      ||                     ||:::.|...:
Mosquito   366 FYIDCLCLLPLDFLYLSIGFNSILR------SF---------------------RLVKIYRFWAF 403

  Fly   897 VSQWEEVYILQNLQKKSADRRGRMNRKDKDGLTKSNLILKFLNMASVFMRIFNLICMMLLIGHWS 961
            :.:.|                                  :..|..::| |..:||..:|:|.||:
Mosquito   404 MDRTE----------------------------------RHTNYPNLF-RSTSLIHYLLVIFHWN 433

  Fly   962 GCLQFLVPMLQGFPSNSWV-----SINELQESYWLEQYSWALFKAMSHMLCIGYGRFP-PQSLTD 1020
            |||..::....||.|.:||     |.:.:::  :|:.|.|......:      .|..| |:|..:
Mosquito   434 GCLYHIIYKNNGFGSKNWVYHDSESADVVKQ--YLQSYYWCTLALTT------IGDLPRPRSKAE 490

  Fly  1021 MWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFE 1085
            ....:..::.|...:|..|||..|::.|:.::|::::.|:..|:.||..|::|..::.::.::|:
Mosquito   491 YVFVIAQLLFGLMLFATVLGHVANIVTSVSAARKEFQAKLDGVKTYMRMRRVPNHLQVKVIKWFD 555

  Fly  1086 HRY-QGKFFDEELILGELSEKLREDV-INYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPG 1148
            :.: ..|..|||..:..|.:||:.:: ||.:..:| ..|..|.|.::.|:.::|.||:..:|.||
Mosquito   556 YLWLTQKCSDEERAVSCLPDKLKAEIAINVHLDTL-KRVEIFQNTEAGFLCELVLKLRPVLFSPG 619

  Fly  1149 DIIIKEGTIGTKMYFIQEGVVDIVMANGE-VATSLSDGSYFGEICLLT--------NARRVASVR 1204
            |.|.::|.:|.:||.:..|.:.:|..||: |..||..|||||||.:|.        ..||.||||
Mosquito   620 DFICRKGEVGKEMYIVNRGRLQVVADNGKTVMASLKAGSYFGEISILNMGTAGKALGNRRTASVR 684

  Fly  1205 AETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNP 1248
            :..|.:||.||......||.:||..|..:|.:|.:||.|..|.|
Mosquito   685 SVGYSDLFVLSKKDMWDVLKEYPAARVRLEAIAVKRLEKYKKAP 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ih	NP_001033948.1	Ion_trans_N	709..751	CDD:400630	10/44 (23%)
		PLN03192	741..>1214	CDD:215625	132/497 (27%)
LOC4576205	XP_061498773.1	None