Protein Alignment Ih and sei

DIOPT Version :10

• Sequence 1: NP_001033948.1
• Gene: Ih / 36589
• FlyBaseID: FBgn0263397
• Length: 1327
• Species: Drosophila melanogaster
• Sequence 2: NP_476713.1
• Gene: sei / 37843
• FlyBaseID: FBgn0003353
• Length: 855
• Species: Drosophila melanogaster
• Alignment Length: 699
• Identity: 165/699 - (23%)
• Similarity: 272/699 - (38%)
• Gaps: 176/699 - (25%)

  Fly   589 PYPARPTSTSCTNSFNRRHIRRHKGKL--GDRLLSGDSEESVRCSY------------------- 632
            |..::|:......|| ::.|:..|.||  .:..:|...|..:.|||
  Fly   178 PLESKPSQHKKQKSF-KKCIKCDKKKLYIKNYQVSARRECDLLCSYDPLRKNNADLFQTHKGTSY 241

  Fly   633 -CSVLNVNDNDLRISFENTCTDSLVTAFDDEALLICDQGTEMVHFDDVSLYGTPKEEPMPNIPIV 696
             |...|:..|......:|...:|.....|.||||                 |: |.||....|
  Fly   242 ECMFKNLKYNQAEKPTDNVMGNSYDDMLDKEALL-----------------GS-KSEPKGQDP-- 286

  Fly   697 SEKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCML 761
                                 |.:...|.|:  .|:.::::......|.:...|.|:..||..:|
  Fly   287 ---------------------NDMITSLGGN--ILLDQKLQNNYYHKWTLLHYSPFKAVWDWIIL 328

  Fly   762 LLLVANLIILPVAISFF--NDDLSTR---------WIAFNCLSDTIFLIDIVVNFRTGIMQQDNA 815
            :|::...|..|...:|.  ..|...|         .:..:.:.|..|::||::||||..:  ::.
  Fly   329 ILVMYTAIFTPYVAAFLLGEQDYQRRNSKYINSDPIVIIDLIVDVTFIVDIIINFRTTFV--NSQ 391

  Fly   816 EQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAK 880
            ::|:..|..||.|||..||.:||::::|.|.:.:          .||:.:         ...|..
  Fly   392 DEVVSHPGRIAVHYLSGWFLIDLVAAVPFDLLLV----------GSDTDE---------TTTLIG 437

  Fly   881 LLSLVRLLRLSRLVRYVSQWEE----VYILQNLQKKSADRRGRMNRKDKDGLTKSNLILKFLNMA 941
            ||...|||||.|:.|.:.::.|    |.||
  Fly   438 LLKTARLLRLVRVARKIDRYSEYGAAVLIL----------------------------------- 467

  Fly   942 SVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSIN---------ELQESYW------- 990
                    |:...:||.||..|:.:.:    |....|..|.|         ::||.|:
  Fly   468 --------LMATFILIAHWLACIWYAI----GNAEKSIASKNIGWLNSLAYDIQEPYFDNRTGGP 520

  Fly   991 --LEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSR 1053
              ..:|..||:...:.:..:|:|...|.:..:...|:..|:.|:..||...|:.:.:||.|.|..
  Fly   521 SIKSRYITALYFTFTSLTSVGFGNVAPNTDAEKAFTICVMLVGSLMYASIFGNVSAIIQRLYSGT 585

  Fly  1054 RQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRY---QGKFFDEELILGELSEKLREDVINYNC 1115
            .:|..::.:|.|::.:.::|..:|||:.|||:|.:   .|  .|...:|....|.|:.|:..:..
  Fly   586 ARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWTYTNG--IDMNSLLKGFPECLQADICLHLN 648

  Fly  1116 RSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVAT 1180
            |.|:.:...|:.|....:.....|.|.....||||::..|.:.|.:|||..|.::|..|...|..
  Fly   649 RKLLTTCAAFSEASPGCLRAFSLKFKTTHAPPGDILVHRGDVLTSLYFIARGSIEIQRAGNIVVL 713

  Fly  1181 SLSDGSYFGE-ICLL-TNARRVASVRAETYCNLFSLSVDHFNCVLDQYP 1227
            ..:|  .||| .|:. |..:....|||.|||::..|..|....|||.||
  Fly   714 GKND--IFGENPCIYPTVGKSNGVVRALTYCDIHKLHRDDLLDVLDSYP 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ih	NP_001033948.1	Ion_trans_N	709..751	CDD:400630	5/41 (12%)
		PLN03192	741..>1214	CDD:215625	126/510 (25%)
sei	NP_476713.1	Ion_trans	322..583	CDD:459842	74/328 (23%)
		CAP_ED	657..767	CDD:237999	36/106 (34%)