Protein Alignment Ih and CngB

DIOPT Version :9

• Sequence 1: NP_001033948.1
• Gene: Ih / 36589
• FlyBaseID: FBgn0263397
• Length: 1327
• Species: Drosophila melanogaster
• Sequence 2: NP_611607.2
• Gene: CngB / 37479
• FlyBaseID: FBgn0266346
• Length: 1040
• Species: Drosophila melanogaster
• Alignment Length: 1163
• Identity: 235/1163 - (20%)
• Similarity: 410/1163 - (35%)
• Gaps: 360/1163 - (30%)

  Fly   256 SFLRTNKIKEQSKKLRNLSLKTRTAKKKGQIISKSNAVSDNSLHPGDKYLNLYLVEKKHSLQPQV 320
            |..|..|:..||:||.        .:....::..|..:.:|.     .|.....::..|.|..::
  Fly     3 SMARFRKVNRQSEKLE--------PEASASLLKSSPNILENF-----AYDEFQPIQTNHPLLKRM 54

  Fly   321 ASTSSSINTTHPQA-SSAPASSSSTCTKAPQLPALSAVAARQQQLLLNGSLKGKGQSQSQGQSRQ 384
            |:|        |.| |.:.:|||||.:.....|.......|      :..::.....|.:...|.
  Fly    55 ATT--------PVAQSGSQSSSSSTSSTRKAEPKFCDTLER------HAFMRNVINQQPESTRRY 105

  Fly   385 TLPGHR-ASVRSESGSGSSHTIPATGKSPPVPHSLAAKISSSASGSKNC---------NLLSASS 439
            :.||.: |.||.     |...|....|          :|....|.::..         .:.|...
  Fly   106 STPGEKEAQVRR-----SLEEITKDLK----------EIEQFVSATEELMQREKEQEQMMYSNKE 155

  Fly   440 NSC--------HKLNAHAQGSGAGSGSGSGSGSGPPGHSHYAAASPKSSVS----SNGHLNKYCL 492
            |.|        :|:||:               ..||  ..:...||:...|    .||.:.  |:
  Fly   156 NKCPSPVKRVTYKINAY---------------KAPP--RRHRPGSPRFYHSRLYFRNGKIG--CV 201

  Fly   493 TDLTRRKAEFNRQLSAPTDYTHHSSSNGSQQEGSSEANEGHEPVGESTITVASAGVSYPHPYSYP 557
                              |.|.|.::.|:                               .::..
  Fly   202 ------------------DSTEHQNNVGA-------------------------------THALV 217

  Fly   558 YHYAHHASSATAPANLKASLQLHSFGSHHPCPYP-ARPTSTSCTNSFNRRHIRRHKGKLGDRLLS 621
            .|..||.....:|.:::..|:..||   ...|.| |.|.......:..|  ........|..:|.
  Fly   218 KHILHHEKPLVSPDSVRRVLEQDSF---EMVPLPGAVPEIVPDPIAIQR--AEELAAATGQVVLP 277

  Fly   622 GDSEESVRCSYCSV------LNVNDNDLRISF----------ENTCTDSLVTAFDDEALLICDQG 670
            .:.||..:.|....      ::.::.|::|.:          .|..|....:..:.|.:.:.:..
  Fly   278 KEEEEEEKSSPLHQVESQPDVDEDEQDVQICYNESPELQNEDRNERTQRTPSINESEIVAVDEPD 342

  Fly   671 TEMVHFDDVSLYGTPKEEPMPNIPIVSEKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKER 735
            |||         .:..:...|:        ||..|.||.|.:.:.....| ::.|.:|...||.|
  Fly   343 TEM---------NSDVDHRKPS--------SAGSLDSQGQQFLRDQVRHL-VRRFTARANKVKSR 389

  Fly   736 IR---QKTSGHWV----------IHP--------------------------------CSSF--- 752
            |.   ..:|...|          :||                                |||.
  Fly   390 IELPPTPSSSSTVSSPSPPPTKSLHPSPQHKVRLVPAGQSPHRGRLFEADTPRSNVWLCSSLCGA 454

  Fly   753 -----------RFY--WDLCML-LLLVANLIILPVAISF-FNDDLSTR-WIAFNCLSDTIFLIDI 801
                       :.|  | ||:: |..:.|..::|:..|| |....:|. |:|.:..:|.|:|:|:
  Fly   455 NNDERTLDPQGKIYISW-LCVVSLSFLYNAWVIPLRASFPFQTKENTNIWLACDFCADIIYLLDV 518

  Fly   802 VVNFRTGIMQQDNAEQVILDPKLIAKHYLR-TWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQ 865
            |. |:..:|.......| .:..|..|:|:| ..|.|||::.:||:.::.
  Fly   519 VF-FKHRVMYLFEGFWV-KNKNLTRKNYMRKLQFKLDLLALLPLELLYF---------------- 565

  Fly   866 ILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYILQNLQKKSADRRGRMNRKDKDGLTK 930
                          ||.:....||..|..:..|.||...:|        ||
  Fly   566 --------------KLGTQAVWLRFPRFFKIQSFWEVFRLL--------DR-------------- 594

  Fly   931 SNLILKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYS 995
                   :..:..|:|:...:..||.:.|.:..|.:.....||...|.||
  Fly   595 -------VISSPHFVRVAKTLTYMLYMIHITAALYYAYSDYQGLGQNRWV--------------- 637

  Fly   996 WALFKAMSH--MLCIGY--------GRFP-PQSLTDMWLTMLSMISGATCYALFLGHATNLIQSL 1049
               |....|  :.|..:        |:.| |:...:.....::.:.|...:||.:|...::|.:.
  Fly   638 ---FSGKGHPYVRCFAFATKTATSIGKNPKPERQGEYVFMTVAWLMGVFVFALLIGQIRDIISTA 699

  Fly  1050 DSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRY-QGKFFDEELILGELSEKLREDV-IN 1112
            ..::.:||:...:..|||....|.::::.|:..:|:..: |.:..||..||..|...|:.|: |:
  Fly   700 TRNKHEYRQLEDETLEYMRRLNLSQEVQSRVKMWFQFTWEQQRTLDESNILDALPINLKTDIAIS 764

  Fly  1113 YNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIV--MAN 1175
            .:.::| :.|..||:.:...:.|:|.||:...|.|||.:.::|.:|.:||.::.|.|.::  .::
  Fly   765 VHIQTL-SKVQLFADCEEALLRDLVLKLRAVTFLPGDFVCRKGEVGREMYIVKLGQVQVMGGPSS 828

  Fly  1176 GEVATSLSDGSYFGEICLL-TNA--RRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVA 1237
            ..|..:|::||.||||.|| .|.  ||.|.||::.|.|||.||....|.|:..||..:..::..|
  Fly   829 DVVLATLTEGSVFGEISLLGINGADRRTADVRSKGYSNLFVLSKSDLNEVIAYYPTAQAILKKRA 893

  Fly  1238 AERLNKIGKNPNIMHQKDEQ-------------LSNPES-----NTITAVVNALAAEA 1277
            .:.:.|     |...:::|:             :.||::     ..:..|:.||..|:
  Fly   894 RQLMRK-----NAAREREEERERARSALQADVVIGNPKTPETAPKLLQTVIQALPFES 946

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ih	NP_001033948.1	Ion_trans_N	709..751	CDD:285597	13/86 (15%)
		Ion_trans	771..1054	CDD:278921	58/296 (20%)
		Crp	1118..>1241	CDD:223736	45/127 (35%)
		CAP_ED	1124..1233	CDD:237999	42/113 (37%)
CngB	NP_611607.2	Ion_trans	488..704	CDD:278921	57/294 (19%)
		DUF4105	<672..755	CDD:290123	19/82 (23%)
		Crp	769..>898	CDD:223736	45/129 (35%)
		CAP_ED	775..889	CDD:237999	42/113 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445371
Domainoid	1	1.000	45	1.000	Domainoid score	I4624
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.850