DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ih and Cnga2

DIOPT Version :9

Sequence 1:NP_001033948.1 Gene:Ih / 36589 FlyBaseID:FBgn0263397 Length:1327 Species:Drosophila melanogaster
Sequence 2:NP_031750.2 Gene:Cnga2 / 12789 MGIID:108040 Length:664 Species:Mus musculus


Alignment Length:610 Identity:145/610 - (23%)
Similarity:274/610 - (44%) Gaps:110/610 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   744 WVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFND---DLSTRWIAFNCLSDTIFLIDIVVNF 805
            :|:.|...:.:.|...:.:.::.|..:| ||.:.|:|   :....|:..:..|||:::.|:::..
Mouse   133 FVLDPAGDWYYRWLFVIAMPVLYNWCLL-VARACFSDLQRNYFVVWLVLDYFSDTVYIADLIIRL 196

  Fly   806 RTGIMQQDNAEQVILDPKLIAKHYLRT-WFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHA 869
            |||.::|.   .::.|||.:..:|:.| .|.||:.|.||.|.|:....              :|:
Mouse   197 RTGFLEQG---LLVKDPKKLRDNYIHTLQFKLDVASIIPTDLIYFAVG--------------IHS 244

  Fly   870 GRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYILQNLQKKSADRRGRMNRKDKDGLTKSNLI 934
            ..          :...|||..:|:..:..:.|......|:                         
Mouse   245 PE----------VRFNRLLHFARMFEFFDRTETRTSYPNI------------------------- 274

  Fly   935 LKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWV--SINELQESYWLEQYSWA 997
                      .||.||:..:|:|.||:.|:.:.:....||..::||  :|.:.:..|...:|.:.
Mouse   275 ----------FRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYC 329

  Fly   998 LFKAMSHMLCIGYGRFPPQSLTDMWL-TMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVK 1061
            |:  .|.:.....|..||....:.:| .:...:.|...:|..:|:..::|.:::::|.:::.|:.
Mouse   330 LY--WSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKID 392

  Fly  1062 QVEEYMAYRKLPRDMRQRITEYFEHRYQG-KFFDEELILGELSEKLREDV-INYNCRSLVASVPF 1124
            .|:.||.:||:.:||..::.::|::.:.. |..||..:|..|..|||.:: ||.:. |.:..|..
Mouse   393 AVKHYMQFRKVSKDMEAKVIKWFDYLWTNKKTVDEREVLKNLPAKLRAEIAINVHL-STLKKVRI 456

  Fly  1125 FANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATS-LSDGSYF 1188
            |.:.::..:.::|.||:.:||.|||.|.::|.||.:||.|:||.:.:|..:|....: ||.||.|
Mouse   457 FQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCF 521

  Fly  1189 GEICLLT------NARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERL------ 1241
            |||.:|.      ..||.|::|:..|.:||.||.|.....:.:||..:|.:|....|.|      
Mouse   522 GEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKKVLEERGREILMKEGLL 586

  Fly  1242 --NKIGKNPNI-MHQKDEQLSNPESNTITAVVNALAAEADDCKDDDMDLKENLLHGSESSIAEPV 1303
              |::..:..: :.:|.|||........|.....||...                |::..:.:.:
Mouse   587 DENEVAASMEVDVQEKLEQLETNMETLYTRFARLLAEYT----------------GAQQKLKQRI 635

  Fly  1304 QTIREGLPRPRSGEFRALFEG-NTP 1327
            ..:...:.:....::  |.:| |||
Mouse   636 TVLETKMKQNHEDDY--LSDGINTP 658

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
IhNP_001033948.1 Ion_trans_N 709..751 CDD:285597 2/6 (33%)
Ion_trans 771..1054 CDD:278921 60/289 (21%)
Crp 1118..>1241 CDD:223736 45/129 (35%)
CAP_ED 1124..1233 CDD:237999 42/115 (37%)
Cnga2NP_031750.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..61
Ion_trans 142..384 CDD:395416 62/306 (20%)
Radical_SAM 417..>470 CDD:418514 13/53 (25%)
CAP_ED 456..572 CDD:237999 42/115 (37%)
CLZ 572..639 CDD:406832 12/82 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1073751at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

Return to query results.
Submit another query.