Protein Alignment Ih and CNGA3

DIOPT Version :9

• Sequence 1: NP_001033948.1
• Gene: Ih / 36589
• FlyBaseID: FBgn0263397
• Length: 1327
• Species: Drosophila melanogaster
• Sequence 2: XP_011508856.1
• Gene: CNGA3 / 1261
• HGNCID: 2150
• Length: 749
• Species: Homo sapiens
• Alignment Length: 873
• Identity: 204/873 - (23%)
• Similarity: 361/873 - (41%)
• Gaps: 195/873 - (22%)

  Fly   510 TDYTHHSSSNGSQQEGSSEANEGHEPVGESTITVASAGVSYPHPYSYPYHYAHHASSATAPANLK 574
            |.|:|.|.::...:....:.|.            |..|:|           ..|:||....:.|:
Human     6 TQYSHPSRTHLKVKTSDRDLNR------------AENGLS-----------RAHSSSEETSSVLQ 47

  Fly   575 ASLQLHSFGSHHPCPYPARPTSTSCTNSFNRRHIRRHKGKLGDRLLSGDSEESVRCS-------- 631
            ..:.:.:           |..:.|...||..:.|.|. |::..:   ...|:.||.:
Human    48 PGIAMET-----------RGLADSGQGSFTGQGIARF-GRIQKK---SQPEKVVRAASRGRPLIG 97

  Fly   632 ---YCSVLNVNDNDLRISFENTCTDSLVTAFDDEALLICDQGTEMVHFDDVSLYGTPKEEPMPNI 693
               :|:....:::::.::....|:............|:.......||..|......|.......:
Human    98 WTQWCAEDGGDESEMALAGSPGCSSGPQGRLSRLIFLLRRWAARHVHHQDQGPDSFPDRFRGAEL 162

  Fly   694 PIVSEKVS---ANFLKSQLQSWFQPTD-NRLA---MKLFGSRKALVKERIRQKTSGHWVIHPCSS 751
            ..||.:.|   || :.||     :|.| .|.|   .|...:.....:|..:.|.....|:.|.|:
Human   163 KEVSSQESNAQAN-VGSQ-----EPADRGRSAWPLAKCNTNTSNNTEEEKKTKKKDAIVVDPSSN 221

  Fly   752 FRFYWDLCMLLLLVANLIILPVAISFFN----------DDLSTR----WIAFNCLSDTIFLIDIV 802
            ..:.|       |.|  |.|||   |:|          |:|.:.    |:..:..:|.::::|::
Human   222 LYYRW-------LTA--IALPV---FYNWYLLICRACFDELQSEYLMLWLVLDYSADVLYVLDVL 274

  Fly   803 VNFRTGIMQQDNAEQVILDPKLIAKHY-LRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQI 866
            |..|||.::|.   .::.|...:.:|| ..|.|.||::|.:|.|..:
Human   275 VRARTGFLEQG---LMVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAY------------------ 318

  Fly   867 LHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYILQNLQKKSADRRGRMNRKDKDGLTKS 931
            |..|.....:|..      |||:.|||..:..:.|                           |::
Human   319 LKVGTNYPEVRFN------RLLKFSRLFEFFDRTE---------------------------TRT 350

  Fly   932 NLILKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWV--SINELQESYWLEQY 994
            |    :.||    .||.||:..:|:|.||:.|:.|.:....||.::|||  :|:..:......:|
Human   351 N----YPNM----FRIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISIPEHGRLSRKY 407

  Fly   995 SWALFKAMSHMLCIGYGRFPPQSLTDMWL-TMLSMISGATCYALFLGHATNLIQSLDSSRRQYRE 1058
            .::|:  .|.:.....|..||....:.:| .::..:.|...:|..:|:..::|.::::||.:::.
Human   408 IYSLY--WSTLTLTTIGETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSMISNMNASRAEFQA 470

  Fly  1059 KVKQVEEYMAYRKLPRDMRQRITEYFEHRYQG-KFFDEELILGELSEKLREDV-INYNCRSLVAS 1121
            |:..:::||.:||:.:|:..|:..:|::.:.. |..||:.:|..|.:||:.:: ||.:..:| ..
Human   471 KIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTL-KK 534

  Fly  1122 VPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVA-TSLSDG 1185
            |..|.:.::..:.::|.||:..||.|||.|.|:|.||.:||.|.||.:.:|..:|... ..||||
Human   535 VRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGVTQFVVLSDG 599

  Fly  1186 SYFGEICLL------TNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTME---------- 1234
            ||||||.:|      :..||.|::|:..|.:||.||.|.....|.:||..:|.:|
Human   600 SYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPEAKKALEEKGRQILMKD 664

  Fly  1235 TVAAERLNKIGKNPNIMHQKDEQLSNPESNTITAVVNALAAEADDCKDDDMDLKENLLHGSESSI 1299
            .:..|.|.:.|.:|..:.:|.|||.:......|.....||    :.....|.:|:.|     |.:
Human   665 NLIDEELARAGADPKDLEEKVEQLGSSLDTLQTRFARLLA----EYNATQMKMKQRL-----SQL 720

  Fly  1300 AEPVQTIREGLPRPRSGEFRALFEGNTP 1327
            ...|          :.|..:.|.:|..|
Human   721 ESQV----------KGGGDKPLADGEVP 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ih	NP_001033948.1	Ion_trans_N	709..751	CDD:285597	9/45 (20%)
		Ion_trans	771..1054	CDD:278921	67/300 (22%)
		Crp	1118..>1241	CDD:223736	50/139 (36%)
		CAP_ED	1124..1233	CDD:237999	46/115 (40%)
CNGA3	XP_011508856.1	Ion_trans	241..465	CDD:278921	61/287 (21%)
		Crp	531..>701	CDD:223736	58/170 (34%)
		CAP_ED	537..653	CDD:237999	46/115 (40%)
		CLZ	653..723	CDD:293134	16/78 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920