Protein Alignment Ih and cnga2b

DIOPT Version :10

• Sequence 1: NP_001033948.1
• Gene: Ih / 36589
• FlyBaseID: FBgn0263397
• Length: 1327
• Species: Drosophila melanogaster
• Sequence 2: XP_073805825.1
• Gene: cnga2b / 103911065
• ZFINID: ZDB-GENE-050307-2
• Length: 682
• Species: Danio rerio
• Alignment Length: 639
• Identity: 144/639 - (22%)
• Similarity: 276/639 - (43%)
• Gaps: 152/639 - (23%)

  Fly   714 QPTDNRLAMKLFGSRKALVKERIRQKTSGHW---VIHPCSSFRFYWDLCMLLLLVANLIILPVAI 775
            ||..|       |:.|.:.|::        |   ::.......:||...:...::.|.::|....
Zfish   126 QPDAN-------GNTKGITKKQ--------WETFIVASSDDTYYYWLFFIAAAVLYNWVLLVARA 175

  Fly   776 SFFNDDLSTR----WIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTW-FF 835
            .|  |.|.:.    |:..:.:.|.::::|..:..|||.::|.   .::.|...:...|:.|: |.
Zfish   176 CF--DQLQSETPIVWLVLDYICDFVYILDSCIRLRTGYLEQG---LLVKDLAKLRDSYIHTFQFK 235

  Fly   836 LDLISSIPLDYIFLI---------FNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLS 891
            ||::|.:|.|..::|         ||                                 ||||.|
Zfish   236 LDVLSILPTDLAYIITGINTPQLRFN---------------------------------RLLRFS 267

  Fly   892 RLVRYVSQWEEVYILQNLQKKSADRRGRMNRKDKDGLTKSNLILKFLNMASVFMRIFNLICMMLL 956
            |:..:.::.|                           |::       |..::| ||:||:..:|:
Zfish   268 RMFEFFNRTE---------------------------TRT-------NYPNIF-RIWNLVLYILV 297

  Fly   957 IGHWSGCLQFLVPMLQGFPSNSWV--SINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLT 1019
            |.||:.|:.:.:....||.|:.||  :|:..:|......|.:..:  .|.:.....|..||....
Zfish   298 IIHWNACIFYAISKSLGFGSDEWVYPNISSTEEGALRRSYIYCFY--WSTLTLTTIGEMPPPVRD 360

  Fly  1020 DMWL-TMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEY 1083
            :.:: .:...:.|...:|..:|:..::|.:::::|.:::.::..::.||.:||:.|.:..|:.::
Zfish   361 EEYVFVVFDFLVGVLIFATIVGNVGSMISNMNATRAEFQARIDAIKHYMHFRKVSRHLETRVIKW 425

  Fly  1084 FEHRYQG-KFFDEELILGELSEKLREDV-INYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQ 1146
            |::.:.. |..||:.:|..|.:|||.:: ||.:..:| ..|..|.:.::..:.::|.||:.:|:.
Zfish   426 FDYLWTNQKAVDEQEVLKNLPDKLRAEIAINVHLTTL-KKVRIFQDCEAGLLVELVLKLRPQVYS 489

  Fly  1147 PGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATS-LSDGSYFGEICLLT------NARRVASVR 1204
            |||.|.::|.||.:||.|:||.:.:|..:|....: |:.|..||||.:|.      ..||.|::|
Zfish   490 PGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQFALLTAGGCFGEISILNIQGSKMGNRRTANIR 554

  Fly  1205 AETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNK-------IGKNPNIMHQKDEQLSNPE 1262
            :..|.:||.||.|.....:.:||..::.:|....|.|.|       |.:...::...||::...|
Zfish   555 SIGYSDLFCLSKDDLMEAVIEYPDAQRVLEERGREILRKQGLLDEGIAQGGLLVMDTDEKVERLE 619

  Fly  1263 SN-------------TITAVVNAL-----AAEADDC-------KDDDMDLKENL 1291
            .:             ..||....|     |.|...|       .|.:||::.|:
Zfish   620 GSLDILQARFARLLGEFTATQRKLKQRITALERQLCHTGIGLVSDHEMDVESNV 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ih	NP_001033948.1	Ion_trans_N	709..751	CDD:400630	7/39 (18%)
		PLN03192	741..>1214	CDD:215625	115/501 (23%)
cnga2b	XP_073805825.1	None