Protein Alignment Ih and cnga2

DIOPT Version :10

• Sequence 1: NP_001033948.1
• Gene: Ih / 36589
• FlyBaseID: FBgn0263397
• Length: 1327
• Species: Drosophila melanogaster
• Sequence 2: XP_004916824.1
• Gene: cnga2 / 100494874
• XenbaseID: XB-GENE-992758
• Length: 675
• Species: Xenopus tropicalis
• Alignment Length: 611
• Identity: 163/611 - (26%)
• Similarity: 278/611 - (45%)
• Gaps: 125/611 - (20%)

  Fly   733 KERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTR----WIAFNCLS 793
            |::..:|....:|:.|...:.:.|.|.:.|.::.|..:|.|...|  |||.|.    |...:.:.
 Frog   133 KKKNDRKVCELFVVDPSGKWYYRWLLVITLPVLYNWFLLVVRACF--DDLQTSYVALWFTLDYIC 195

  Fly   794 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRT-WFFLDLISSIPLDYIFLIFNQIMKL 857
            |.|::.|||:.||||.::|.   .::.|||.::.:|:|| .|.||:||.:|.|..:.
 Frog   196 DVIYIADIVIRFRTGFLEQG---LLVRDPKTLSNNYIRTLQFKLDIISILPTDLGYF-------- 249

  Fly   858 QDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYILQNLQKKSADRRGRMNR 922
                          |:.|.|  ..|...|||...|:.....|.|......|:
 Frog   250 --------------AVGIHR--PELRFNRLLHFPRMFECFDQTETRTSYPNI------------- 285

  Fly   923 KDKDGLTKSNLILKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWV--SINEL 985
                                  .|||||:..:|||.||:||:.:......||.::|||  ::.:.
 Frog   286 ----------------------FRIFNLVLYILLIIHWNGCIYYAFSKAIGFGADSWVYPNLTDP 328

  Fly   986 QESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTD--MWLTMLSMISGATCYALFLGHATNLIQS 1048
            :..|...:|.:.|:.:...:..||   ..||.:||  ....:...:.|...:|..:|:..::|.:
 Frog   329 KHGYLAREYVYCLYWSTLTLTTIG---DTPQPMTDTEYLFVIFDFLVGVLIFATIVGNVGSMISN 390

  Fly  1049 LDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQG-KFFDEELILGELSEKLREDV-I 1111
            ::::|.:::.|:..::.||.:|::.:|:..::..:|::.:.. |..||..:|..|.:|||.:: |
 Frog   391 MNATRTEFQSKIDAIKHYMQFRRVSKDLEAKVILWFDYLWTNKKTVDEREVLKNLPDKLRAEIAI 455

  Fly  1112 NYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANG 1176
            |.:..:| ..|..|.|.::..:.::|.||:.:||.|||.|.::|.||.:||.|:||.:.:|..:|
 Frog   456 NVHLDTL-KKVRIFQNCEAGLLVELVLKLRPQVFSPGDYICRKGDIGREMYIIKEGKLAVVGEDG 519

  Fly  1177 EVATS-LSDGSYFGEICLLT------NARRVASVRAETYCNLFSLSVDHFNCVLDQYP------- 1227
            ....: |:.||.||||.:|.      ..||.||:|:..|.:||.||.|.....|.:||
 Frog   520 ITHYAVLTSGSCFGEISILNIEGSKMGNRRTASIRSIGYSDLFCLSKDDLMEALVEYPDAKKILE 584

  Fly  1228 -----------LMRKTMETVAA------ERLNKIGKNPNIMHQKDEQLSNPESN---TITAVVNA 1272
                       |:.:|.|.::.      |||..:..|.:|:|.:..:|....||   |:...|..
 Frog   585 ERGREILIKEGLLDETKEKISVKGKSSEERLELVESNLDILHTRFARLLREYSNAQQTLKQRVTL 649

  Fly  1273 LAAEADDCKDDDMDLKENLLHGSESS 1298
            |            :||...:||.|.|
 Frog   650 L------------ELKLRDIHGGEVS 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ih	NP_001033948.1	Ion_trans_N	709..751	CDD:400630	4/17 (24%)
		PLN03192	741..>1214	CDD:215625	134/490 (27%)
cnga2	XP_004916824.1	Ion_trans	153..395	CDD:459842	76/308 (25%)
		CAP_ED	467..583	CDD:237999	43/115 (37%)
		CLZ	583..651	CDD:465160	15/79 (19%)