Protein Alignment Ih and cnga3

DIOPT Version :10

• Sequence 1: NP_001033948.1
• Gene: Ih / 36589
• FlyBaseID: FBgn0263397
• Length: 1327
• Species: Drosophila melanogaster
• Sequence 2: XP_031752880.1
• Gene: cnga3 / 100494840
• XenbaseID: XB-GENE-948568
• Length: 737
• Species: Xenopus tropicalis
• Alignment Length: 621
• Identity: 154/621 - (24%)
• Similarity: 281/621 - (45%)
• Gaps: 119/621 - (19%)

  Fly   733 KERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTR----WIAFNCLS 793
            |::..:|....:||.|.|:..:.|...:.:.::.|...|.....|  |:|...    |:..:..:
 Frog   190 KKKEEEKKKEIFVIDPSSNLYYRWLSIISVPVLYNWCFLVCRACF--DELQRNSIILWLVLDYTA 252

  Fly   794 DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRT-WFFLDLISSIPLDYIFLIFNQIMKL 857
            |.|::.|.:|.||||.::|.   .::.|.|.:.::|.:| .|.|||:|.:|.|..:|
 Frog   253 DVIYITDTLVRFRTGFLEQG---LLVKDAKKLKENYSKTRQFKLDLLSLLPTDLTYL-------- 306

  Fly   858 QDFSDSFQILHAGRALRILRLAKL------LSLVRLLRLSRLVRYVSQWEEVYILQNLQKKSADR 916
                                  |:      |...||||..|:..:..:.|
 Frog   307 ----------------------KIGLNYPELRFNRLLRFGRMFEFFDRTE--------------- 334

  Fly   917 RGRMNRKDKDGLTKSNLILKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVS 981
                        |::       |..::| ||.||:..:|:|.||:.|:.|.:....||.:::||.
 Frog   335 ------------TRT-------NYPNIF-RIGNLVLYILIIIHWNACIYFAISKAIGFGTDTWVY 379

  Fly   982 INELQESY--WLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATN 1044
            .|.....|  ...:|.::|:.:...:..||... ||....:....:...:.|...:|..:|:..:
 Frog   380 PNISHPEYGRLARKYIYSLYWSTLTLTTIGETP-PPVKDIEFLFVVFDFLIGVLIFATIVGNVGS 443

  Fly  1045 LIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQG-KFFDEELILGELSEKLRE 1108
            :|.::::|:.:::.|:..:::||.:||:.:|:..|:.::|::.:.. |..||:.:|..|.:||:.
 Frog   444 MISNMNASKAEFQSKIDSIKQYMQFRKVTKDLEARVIKWFDYLWTNKKTMDEKEVLKSLPDKLKA 508

  Fly  1109 DV-INYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIV 1172
            :: ||.:..:| ..|..|.:.::..:.::|.||:.:||.|||.|.::|.||.:||.|:||.:.:|
 Frog   509 EIAINVHLDTL-KKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGREMYIIKEGKLAVV 572

  Fly  1173 MANGEVA-TSLSDGSYFGEICLL------TNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMR 1230
            ..:|... ..||||||||||.:|      :..||.|::|:..|.:||.||.|.....|.:||..:
 Frog   573 ADDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPDAK 637

  Fly  1231 KTMET----------VAAERLNKIGKNPNIMHQKDEQLSNPESNTITAVVNALAAEADDCKDDDM 1285
            ..:|.          :..|...|.|.:|..:.:|.|::.....:..|.....||    |.....:
 Frog   638 TVLEEKGRQILMKDGLIDEEAAKAGADPKDVEEKVEKMETAMDSLQTRFARLLA----DYNSTQL 698

  Fly  1286 DLKENL---------LHGSESSIAEPVQTIREGLPR 1312
            .||:.:         .:|..:|  |...:..||.|:
 Frog   699 KLKQRVTKLESQVKKCYGDNAS--EGGDSAAEGDPQ 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ih	NP_001033948.1	Ion_trans_N	709..751	CDD:400630	5/17 (29%)
		PLN03192	741..>1214	CDD:215625	127/494 (26%)
cnga3	XP_031752880.1	Ion_trans	210..452	CDD:459842	65/312 (21%)
		CAP_ED	524..635	CDD:237999	43/110 (39%)
		CLZ	640..709	CDD:465160	13/72 (18%)