Protein Alignment Ih and kcnh8

DIOPT Version :9

• Sequence 1: NP_001033948.1
• Gene: Ih / 36589
• FlyBaseID: FBgn0263397
• Length: 1327
• Species: Drosophila melanogaster
• Sequence 2: XP_031760363.1
• Gene: kcnh8 / 100490406
• XenbaseID: XB-GENE-981673
• Length: 1114
• Species: Xenopus tropicalis
• Alignment Length: 624
• Identity: 141/624 - (22%)
• Similarity: 267/624 - (42%)
• Gaps: 136/624 - (21%)

  Fly   718 NRLAM--KLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISF-FN 779
            |:|.:  .:|..:.||.:.:::......::|...|:|:..||..:||......:.:|..:|| .|
 Frog   184 NKLNLNNNVFVDKPALPEYKVQDAKKSKFIILHFSTFKAAWDWLILLATFYVAVTVPYNVSFEDN 248

  Fly   780 DD-LSTRWIAFNCLS-DTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSI 842
            || .|||....:.:| :.:|:.||::||||..:.:..  |||...:.|..||:.|||.:|||:::
 Frog   249 DDPSSTRSTTVSDISVEILFITDIILNFRTTYVSESG--QVIFKSRSICIHYVTTWFVIDLIAAL 311

  Fly   843 PLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYILQ 907
            |.|.:: .||..:.                 .::.|..||..:|||||.||            ||
 Frog   312 PFDLLY-AFNVTVD-----------------NLVSLVHLLKTIRLLRLLRL------------LQ 346

  Fly   908 NLQKKSADRRGRMNRKDKDGLTKSNLILKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQ 972
            .|.:.|               ..|.::|..            |:.|..|:.||..|:.:::..::
 Frog   347 KLDRYS---------------QHSTIVLTL------------LMSMFALLAHWMACIWYVIGKME 384

  Fly   973 GFPSN---SWVSINELQESYWLEQ-----------------------YSWALFKAMSHMLCIGYG 1011
              ..|   ||       :..||.:                       |..:|:..:|.:..:|:|
 Frog   385 --MKNKPLSW-------DIGWLHELGKRLESPFHSNDSQGGPTIRSTYIASLYFTLSSLTSVGFG 440

  Fly  1012 RFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDM 1076
            .....:..:...::..|:.||..:||..|:.|.:||.:.|....|..:.|.:::::....||:.:
 Frog   441 NVSANTDVEKIFSICIMLIGALMHALVFGNVTAIIQRMYSRWSLYHTRTKDLKDFIRVHHLPQQL 505

  Fly  1077 RQRITEYFEHRYQ-GKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKL 1140
            :||:.|||:..:. ....|...:|.:..::||.|:..|..:.:: .:..|.:|....:..:...:
 Frog   506 KQRMLEYFQTNWSVNNGIDSHELLKDFPDELRSDITMYLNKEIL-QLSLFESASRGCLRSLSLHI 569

  Fly  1141 KYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFG------EICLLTNARR 1199
            |.....||:.::::|.....:|.:..|.:: |:.:|.|...|..|...|      :..:.||
 Frog   570 KTSFCAPGEYLLRQGDALQAIYLVCSGSME-VLKDGMVLAILGKGDLIGANLSIKDQVIKTN--- 630

  Fly  1200 VASVRAETYCNLFSLSVDHFNCVLDQYP-------------LMRKTMETVAAERLNKIGKNPNIM 1251
             |.|:|.|||:|..:.:.....|||.||             |.....|...::|::::... :.:
 Frog   631 -ADVKALTYCDLQCIILKGLYEVLDFYPEYAHTFVEHIQQDLTYNLREGHESDRMSRLSCK-STL 693

  Fly  1252 HQKDEQLSNPESNTITAVVNALAAEADDCKDDDMDLKEN 1290
            .|.|.:.:...:|.::::|          :|:|.|.:|:
 Frog   694 SQTDLRGNGSINNRLSSIV----------EDEDEDTEED 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ih	NP_001033948.1	Ion_trans_N	709..751	CDD:285597	6/34 (18%)
		Ion_trans	771..1054	CDD:278921	75/311 (24%)
		Crp	1118..>1241	CDD:223736	30/141 (21%)
		CAP_ED	1124..1233	CDD:237999	29/127 (23%)
kcnh8	XP_031760363.1	PAS_9	40..135	CDD:404329
		PLN03192	200..>617	CDD:215625	110/486 (23%)
		PRK11753	580..>658	CDD:236969	22/82 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910