DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment conv and RLP14

DIOPT Version :9

Sequence 1:	NP_001286416.1	Gene:	conv / 36588	FlyBaseID:	FBgn0261269	Length:	1092	Species:	Drosophila melanogaster
Sequence 2:	NP_177558.4	Gene:	RLP14 / 843758	AraportID:	AT1G74180	Length:	976	Species:	Arabidopsis thaliana

Alignment Length:	911	Identity:	229/911 - (25%)
Similarity:	354/911 - (38%)	Gaps:	247/911 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 QLHLLRTNLSHVGLLGFGILGKAKELVIDGHAFQQLPKDLFAGQEIANSLGIIRVTNGNLSDLP- 190
            :|.:.:||.....||...:|          |.|::| :.|....||.|..      ||...|:.
plant    83 ELSIGQTNFKESSLLNLSLL----------HPFEEL-RSLNLSGEIYNEF------NGLFDDVEG 130

  Fly   191 IETFQPLRKLKTLDLHGNQLEN-------------------------LKRNQFKNLRELEVLDIS 230
            .|:.:.||.|:.|||..|...|                         |...:.|||.:||:||:|
plant   131 YESLRRLRNLEILDLSSNSFNNSIFPFLNAATSLTTLFIQSNYIGGPLPIKELKNLTKLELLDLS 195

  Fly   231 HNQIKKL--EAQHIADLTKLGWCNVSHNALSELSRGTFARNSVLKVLHLSHNQI-ARLDANSFRG 292
            .:.....  |..|:..|..|.......::|.||.......|  |:||.|:.|.: ..:....|..
plant   196 RSGYNGSIPEFTHLEKLKALDLSANDFSSLVELQELKVLTN--LEVLGLAWNHLDGPIPKEVFCE 258

  Fly   293 MRFLRRLFLSDNVLTDIGRGTFGSIARIGTIDLARNRLKKIEFQMFTQMNYVELLDLAEN----- 352
            |:.||:|.|..|..........|::.::..:||:.|:|.......|..:..:|.|.|::|
plant   259 MKNLRQLDLRGNYFEGQLPVCLGNLNKLRVLDLSSNQLSGNLPASFNSLESLEYLSLSDNNFEGF 323

  Fly   353 -------NITKIE---KNSFKDIYQAIINVSHNALELIE--TAAFENC------------VNITV 393
                   |:||::   .:|..::.|  :....|.|...:  .||...|            .|:.:
plant   324 FSLNPLANLTKLKVFRLSSTSEMLQ--VETESNWLPKFQLTVAALPFCSLGKIPNFLVYQTNLRL 386

  Fly   394 LDLSHNRLANFSRRSFDETTFATYFQLSYNNLTNLAQIP---IQNMTGLKVLNASYNSIT--EIP 453
            :|||.|||:                          ..||   ::|...||||....||.|  :||
plant   387 VDLSSNRLS--------------------------GDIPTWLLENNPELKVLQLKNNSFTIFQIP 425

  Fly   454 KNCFPKLYELHTIDVSHNNISSIF-NGVFQTLFSLRSIDLSHN--------SMREIKSSTF---- 505
                ..:::|..:|.|.|:|:.:. :.:...|..|..::.|||        ||.|:...:|
plant   426 ----TIVHKLQVLDFSANDITGVLPDNIGHVLPRLLHMNGSHNGFQGNLPSSMGEMNDISFLDLS 486

  Fly   506 -----GTLP--------TLLEMDLSHNELVSVVRGSLAKLTSLRQLYLNNNQLEKLF--QLPISL 555
                 |.||        :|:.:.||||.....:.....:||||..|.::||    ||  ::.:.|
plant   487 YNNFSGELPRSLLTGCFSLITLQLSHNSFSGPILPIQTRLTSLIVLRMHNN----LFTGEIGVGL 547

  Fly   556 NELY------FSHNRLTNIPSGTWPVMNS-LIYLDLSHNQLGDTLNGESFTGLLVVQRLK---LQ 610
            ..|.      .|:||||.:.|.:.|..:| ||.|.||:|.|..||.    ..||.:..|.   |.
plant   548 RTLVNLSIFDASNNRLTGLISSSIPPDSSHLIMLLLSNNLLEGTLP----PSLLAIHHLNFLDLS 608

  Fly   611 NNGIS-QPPKDAVAVMSTLQYLHLENNNITTLERSAFGKLPVLFELNLYGNQVKDISKRAFEGLL 674
            .|.:| ..|...|..|..:: :.|.||:.|       |.|||....|.|   :.|:......|.:
plant   609 GNLLSGDLPSSVVNSMYGIK-IFLHNNSFT-------GPLPVTLLENAY---ILDLRNNKLSGSI 662

  Fly   675 -------QLLTLNLSSNGIQTLQNDIFVGLPSLRNLDLSFNSLTKLDNKTNGVLDDLLSLETLDL 732
                   :::||.|..|.:..........|.|:|.||||       |||.|||:...|:..:.:|
plant   663 PQFVNTGKMITLLLRGNNLTGSIPRKLCDLTSIRLLDLS-------DNKLNGVIPPCLNHLSTEL 720

  Fly   733 SH--------NRISF-------VTKKTFPSHQYIPYNLRNLNLSYNLMPILTYDITFGTKKLVRL 782
            ..        ..|||       ..:.||...:::.|                ||.|:   .:|.:
plant   721 GEGIGLSGFSQEISFGDSLQMEFYRSTFLVDEFMLY----------------YDSTY---MIVEI 766

  Fly   783 DVSHNQINDLRRGVISNFTSLQSLDMSYNELSNLKSEEHIFDLPQNLSWLDLSHNKIYHLPFANL 847
            :.:..|..|...|...::  :..||:|.||||.:...| :.|| ..|..|:||.|.:.....||.
plant   767 EFAAKQRYDSFSGGTLDY--MYGLDLSSNELSGVIPAE-LGDL-SKLRALNLSRNLLSSSIPANF 827

  Fly   848 VKVKSLKYVDLTNNSLE-DVPASIVG---------SMRNGSQVL-------------LAGNPLHC 889
            .|:|.::.:||:.|.|: ::|..:..         |..|.|.::             ..||||.|
plant   828 SKLKDIESLDLSYNMLQGNIPHQLTNLTSLAVFNVSFNNLSGIIPQGGQFNTFNDNSYLGNPLLC 892

  Fly   890 G 890
            |
plant   893 G 893

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conv	NP_001286416.1	leucine-rich repeat	125..148	CDD:275380	6/20 (30%)
		leucine-rich repeat	150..175	CDD:275380	6/24 (25%)
		leucine-rich repeat	176..199	CDD:275380	5/23 (22%)
		LRR_8	198..258	CDD:290566	20/86 (23%)
		leucine-rich repeat	200..223	CDD:275380	10/47 (21%)
		LRR_RI	201..545	CDD:238064	102/431 (24%)
		leucine-rich repeat	224..271	CDD:275380	13/48 (27%)
		LRR_8	245..306	CDD:290566	18/61 (30%)
		leucine-rich repeat	272..295	CDD:275380	7/23 (30%)
		LRR_8	296..354	CDD:290566	15/69 (22%)
		leucine-rich repeat	296..319	CDD:275380	6/22 (27%)
		LRR_8	322..401	CDD:290566	24/107 (22%)
		leucine-rich repeat	322..343	CDD:275380	5/20 (25%)
		leucine-rich repeat	344..367	CDD:275380	8/37 (22%)
		leucine-rich repeat	371..390	CDD:275380	5/32 (16%)
		leucine-rich repeat	391..414	CDD:275380	6/22 (27%)
		leucine-rich repeat	416..438	CDD:275380	3/24 (13%)
		LRR_8	437..495	CDD:290566	17/60 (28%)
		leucine-rich repeat	439..462	CDD:275380	9/24 (38%)
		leucine-rich repeat	463..486	CDD:275380	6/23 (26%)
		LRR_RI	486..738	CDD:238064	84/304 (28%)
		LRR_8	486..545	CDD:290566	23/83 (28%)
		leucine-rich repeat	487..510	CDD:275380	11/47 (23%)
		leucine-rich repeat	511..534	CDD:275380	6/22 (27%)
		leucine-rich repeat	535..554	CDD:275380	6/20 (30%)
		LRR_8	554..614	CDD:290566	24/69 (35%)
		leucine-rich repeat	555..578	CDD:275380	9/28 (32%)
		leucine-rich repeat	579..603	CDD:275380	10/23 (43%)
		leucine-rich repeat	604..627	CDD:275380	7/26 (27%)
		LRR_8	626..710	CDD:290566	23/90 (26%)
		leucine-rich repeat	628..649	CDD:275380	5/20 (25%)
		leucine-rich repeat	652..672	CDD:275380	3/19 (16%)
		LRR_8	698..765	CDD:290566	20/81 (25%)
		leucine-rich repeat	700..726	CDD:275380	11/25 (44%)
		leucine-rich repeat	727..745	CDD:275380	4/32 (13%)
		LRR_8	777..839	CDD:290566	19/61 (31%)
		leucine-rich repeat	779..802	CDD:275380	4/22 (18%)
		leucine-rich repeat	829..852	CDD:275380	8/22 (36%)
RLP14	NP_177558.4	LRRNT_2	31..75	CDD:311940
		PLN00113	<107..>322	CDD:331614	56/223 (25%)
		leucine-rich repeat	108..139	CDD:275380	10/37 (27%)
		leucine-rich repeat	140..163	CDD:275380	6/22 (27%)
		leucine-rich repeat	164..188	CDD:275380	4/23 (17%)
		leucine-rich repeat	189..211	CDD:275380	7/21 (33%)
		leucine-rich repeat	212..236	CDD:275380	5/23 (22%)
		leucine-rich repeat	237..261	CDD:275380	7/23 (30%)
		leucine-rich repeat	262..285	CDD:275380	6/22 (27%)
		PLN00113	265..>893	CDD:331614	176/708 (25%)
		leucine-rich repeat	286..309	CDD:275380	5/22 (23%)
		leucine-rich repeat	310..334	CDD:275380	5/23 (22%)
		leucine-rich repeat	335..383	CDD:275380	7/49 (14%)
		leucine-rich repeat	384..402	CDD:275380	8/43 (19%)
		leucine-rich repeat	409..430	CDD:275380	9/24 (38%)
		leucine-rich repeat	431..455	CDD:275380	6/23 (26%)
		leucine-rich repeat	456..479	CDD:275380	7/22 (32%)
		leucine-rich repeat	483..504	CDD:275380	3/20 (15%)
		leucine-rich repeat	505..528	CDD:275380	6/22 (27%)
		leucine-rich repeat	529..552	CDD:275380	8/26 (31%)
		leucine-rich repeat	553..577	CDD:275380	7/23 (30%)
		leucine-rich repeat	578..601	CDD:275380	11/26 (42%)
		leucine-rich repeat	602..627	CDD:275380	7/24 (29%)
		leucine-rich repeat	648..670	CDD:275380	3/24 (13%)
		leucine-rich repeat	671..694	CDD:275380	5/22 (23%)
		leucine-rich repeat	695..716	CDD:275380	12/27 (44%)
		leucine-rich repeat	739..808	CDD:275380	20/91 (22%)
		leucine-rich repeat	809..832	CDD:275380	8/22 (36%)
		leucine-rich repeat	833..856	CDD:275380	5/22 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000