back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment conv and RLP53

DIOPT Version :9

Sequence 1:	NP_001286416.1	Gene:	conv / 36588	FlyBaseID:	FBgn0261269	Length:	1092	Species:	Drosophila melanogaster
Sequence 2:	NP_001332753.1	Gene:	RLP53 / 832764	AraportID:	AT5G27060	Length:	958	Species:	Arabidopsis thaliana

Alignment Length:	926	Identity:	216/926 - (23%)
Similarity:	340/926 - (36%)	Gaps:	270/926 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 NSLGIIRVTNGNLSDLPIETFQPLRKLKTLDLHGNQLENLKRNQ-------FKNLRELEVLDISH 231
            ||..|||:|   ||      |..|.....||:......||.|.:       |||..|:......|
plant     7 NSKSIIRIT---LS------FIFLFICHFLDVLAAPTRNLCRPEQRDALLAFKNEFEIGKPSPDH 62

  Fly   232 NQIKKLEAQHIADLTKLGW-------------CNVSHNALSELS------RGTFARNSVLKVLH- 276
            .:|..:|:....|    .|             ||.....:.||.      .|.|..||.::.||
plant    63 CKIYGIESPRKTD----SWGNNSDCCNWEGVTCNAKSGEVIELDLSCSSLHGRFHSNSSIRNLHF 123

  Fly   277 -----LSHNQIARLDANSFRGMRFLRRLFLSDNVLTDIGRGTFGSIARIGTIDLARNRLKKIEFQ 336
                 ||.|.......:|...:..|..|.||.|..:.....:.|:::|:..::|..|:.......
plant   124 LTTLDLSFNDFKGQITSSIENLSHLTYLDLSSNHFSGQILNSIGNLSRLTYLNLFDNQFSGQAPS 188

  Fly   337 MFTQMNYVELLDLAENNITKIEKNSFKDIYQAIINVSH-NALELIET-------AAFENCVNITV 393
            ....::::..|||:.|..       |.....:|..:|| ..|.|...       ::..|..|:|.
plant   189 SICNLSHLTFLDLSYNRF-------FGQFPSSIGGLSHLTTLSLFSNKFSGQIPSSIGNLSNLTT 246

  Fly   394 LDLSHNRLANFSRR------SFDETTFATYFQ--------LSYNNLTNLAQIPIQ---------- 434
            ||||:|   |||.:      :..:.||...|.        .|:.||..|.::.:.
plant   247 LDLSNN---NFSGQIPSFIGNLSQLTFLGLFSNNFVGEIPSSFGNLNQLTRLYVDDNKLSGNFPN 308

  Fly   435 ---NMTGLKVLNASYNSIT-EIPKNCFPKLYELHTIDVSHNNISSIFNGVFQTLFSLRSIDLSHN 495
               |:|||.:|:.|.|..| .:|.| ...|..|...|.|.|..:..|.....|:.||..|.|:.|
plant   309 VLLNLTGLSLLSLSNNKFTGTLPPN-ITSLSNLMDFDASDNAFTGTFPSFLFTIPSLTYIRLNGN 372

  Fly   496 SMREIKSSTFGTLPT---LLEMDLSHNELVSVVRGSLAKLTSLRQLYLNNNQLE-----KLFQLP 552
            .::  .:..||.:.:   |.|:|:.:|..:..:..|::||..|.:|.:::...:     .:|...
plant   373 QLK--GTLEFGNISSPSNLYELDIGNNNFIGPIPSSISKLVKLFRLDISHLNTQGPVDFSIFSHL 435

  Fly   553 ISLNELYFSH-NRLTNIPSGTW-PVMNSLIYLDLSHNQLGDTLNGESFTG--LLVVQRLKLQNNG 613
            .||.:|..|| |..|.|....: .....|:.||||.|.:..| |..|.:.  ..::|.|.|...|
plant   436 KSLLDLNISHLNTTTRIDLNYFLSYFKRLLLLDLSGNHVSAT-NKSSVSDPPSQLIQSLYLSGCG 499

  Fly   614 ISQPPKDAVAVMSTLQYLHLENNNITTLERSAFGKLPVLFELNLYGNQVKDISKRA--------- 669
            |::.| :.|.....|.:|.:.||.|.........:||:|:.:||..|.:....:.:
plant   500 ITEFP-EFVRTQHELGFLDISNNKIKGQVPDWLWRLPILYYVNLSNNTLIGFQRPSKPEPSLLYL 563

  Fly   670 --------------FEGLLQLLTLNLSSNGI------------QTL------QNDIFVGLPS--- 699
                          ..||..|.||:||.|..            .||      ||.:..|||.
plant   564 LGSNNNFIGKIPSFICGLRSLNTLDLSDNNFNGSIPRCMGHLKSTLSVLNLRQNHLSGGLPKQIF 628

  Fly   700 --LRNLDLSFNSLT-KL----------------DNKTNGVLDDLLS------------------- 726
              ||:||:..|.|. ||                .|:.|......||
plant   629 EILRSLDVGHNQLVGKLPRSLSFFSTLEVLNVESNRINDTFPFWLSSLPKLQVLVLRSNAFHGPI 693

  Fly   727 -------LETLDLSHNRISFVTKKTFPSHQYIPYN----------------------------LR 756
                   |..:|:||||.:    .|.|:..::.::                            |.
plant   694 HEATFPELRIIDISHNRFN----GTLPTEYFVKWSAMSSLGKNEDQSNEKYMGSGLYYQDSMVLM 754

  Fly   757 NLNLSYNLMPILTY--DITFG--------------TKKLVRLDVSHNQINDLRRGVISNFTSLQS 805
            |..::..|:.|||.  .:.|.              .|:|:.|.:|:|..:......:.|.|:|:|
plant   755 NKGVAMELVRILTIYTAVDFSGNRFEGEIPKSIGLLKELLVLSLSNNAFSGHMPSSMGNLTALES 819

  Fly   806 LDMSYNELSNLKSEEHIFDLPQN------LSWLDLSHNKIYHL-PFANLVKVKSLKYVD----LT 859
            ||:|.|:|:.        ::||.      |::::.|||::..| |.......::....:    |.
plant   820 LDVSKNKLTG--------EIPQELGDLSFLAYMNFSHNQLAGLVPGGQQFLTQNCSAFEDNLGLF 876

  Fly   860 NNSLEDV------PAS 869
            .:|||:|      |||
plant   877 GSSLEEVCRDIHTPAS 892

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.