DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment conv and RLP19

DIOPT Version :9

Sequence 1:	NP_001286416.1	Gene:	conv / 36588	FlyBaseID:	FBgn0261269	Length:	1092	Species:	Drosophila melanogaster
Sequence 2:	NP_179112.1	Gene:	RLP19 / 815997	AraportID:	AT2G15080	Length:	983	Species:	Arabidopsis thaliana

Alignment Length:	927	Identity:	235/927 - (25%)
Similarity:	359/927 - (38%)	Gaps:	250/927 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 TNGNLSDLPIETFQPLRKLKTLDLHGNQLENLKRNQFKNLRELEVLDISHNQIKKLEAQHIADLT 246
            :|.:|..||     .||.|.||||..|.......:..:.|..|..||:|.|.........|.:|:
plant   101 SNSSLFRLP-----QLRFLTTLDLSNNDFIGQIPSSLETLSNLTTLDLSRNHFSGRIPSSIGNLS 160

  Fly   247 KLGWCNVSHNALS----------------ELSRGTFARNSVLKVLHLSHNQIARLDANSFRG--M 293
            .|.:.:.|||..|                .||...|:......:.:||:....||..|||.|  .
plant   161 HLIFVDFSHNNFSGQIPSSLGYLSHLTSFNLSYNNFSGRVPSSIGNLSYLTTLRLSRNSFFGELP 225

  Fly   294 RFLRRLF-LSDNVLTD---IGR--GTFGSIARIGTIDLARNR-LKKIEFQMFTQMNYVELLDLAE 351
            ..|..|| |:|.:|..   :|:  .:.|:::.:.:|||.:|. :.:|.|.: ..::.:....|::
plant   226 SSLGSLFHLTDLILDTNHFVGKIPSSLGNLSHLTSIDLHKNNFVGEIPFSL-GNLSCLTSFILSD 289

  Fly   352 NNITKIEKNSFKDIYQA-IINVSHNALELIETAAFENCVNITVLDLSHNRL-----ANFSRRS-- 408
            |||.....:||.::.|. |:||..|.|......|..|...::.|.|.:|||     :|.|..|
plant   290 NNIVGEIPSSFGNLNQLDILNVKSNKLSGSFPIALLNLRKLSTLSLFNNRLTGTLPSNMSSLSNL 354

  Fly   409 --FD--ETTFATYFQLSYNNLTNLAQIPIQNMTGLKVLN--------ASYNSIT--EIPKNCF-- 457
              ||  |..|......|..|:.:|..|.::|    ..||        :||:::|  .:..|.|
plant   355 KLFDATENHFTGPLPSSLFNIPSLKTITLEN----NQLNGSLGFGNISSYSNLTVLRLGNNNFRG 415

  Fly   458 ------PKLYELHTIDVSHNNISSIFN-GVFQTLFSLRSIDLSHNS------MREIKSSTFGTLP 509
                  .||..|..:|:|:.|...:.: .:|..|.|:..::|||.:      |.||.|| |..|.
plant   416 PIHRSISKLVNLKELDLSNYNTQGLVDFTIFSHLKSIEYLNLSHLNTTTTIDMYEILSS-FKLLD 479

  Fly   510 TLLEMDLSHNELVSVVRGSL--AKLTSLRQLYLNN---NQLEKLFQLPISLNELYFSHNRLT-NI 568
            ||   |||.:.:.:..:.||  :.|..:.||||:.   .:..|..:....:..|..|:|::. .:
plant   480 TL---DLSGSHVSTTNKSSLSNSSLVLISQLYLSGCGITEFPKFLRSQELMLTLDISNNKIKGQV 541

  Fly   569 PSGTW--PVMNSLIYLDLSHNQLGDTLNGESFTGLLVVQRLKLQNNGISQPPKDAVAVMSTLQYL 631
            |...|  ||:|   |::||:|         :|.|.  .:..||....|.:||        .::.|
plant   542 PGWLWMLPVLN---YVNLSNN---------TFIGF--ERSTKLGLTSIQEPP--------AMRQL 584

  Fly   632 HLENNNITTLERSAFGKLPVLFELNLYGNQVKDISKRAFEGLL----------QLLTLNLSSNGI 686
            ...|||.|....|...:||.|..|        |.|...|.|.:          .|..|||..|.:
plant   585 FCSNNNFTGNIPSFICELPYLSTL--------DFSNNKFNGSIPTCMGNIQSPYLQALNLRHNRL 641

  Fly   687 Q-TLQNDIFVGLPSLRNLDLSFNSLTKLDNKTNGVLDDLLSLETLDLSHNRISFVTKKTFP---- 746
            . .|..:||   .||.:||:..|.|.   .|....|..:.||..|::..|:||    .|||
plant   642 SGLLPENIF---ESLISLDVGHNQLV---GKLPRSLSHISSLGLLNVESNKIS----DTFPLWLS 696

  Fly   747 SHQYIPYNLRNLNLSYNLMPILTYDITFGTKKLVRLDVSHNQIN-DLRRGVISNFTSLQSLDMSY 810
            |.|.:...:...|..|.  ||.....:    ||..:|:|.||.| .|......|:|::.|||.:.
plant   697 SLQELQVLVLRSNAFYG--PIEKTQFS----KLRIIDISGNQFNGTLPANFFVNWTAMFSLDENE 755

  Fly   811 NE-----LSN--------------------------------------------------LKSEE 820
            ::     :||                                                  |..|.
plant   756 DQSNGETMSNMYMSTDYFYFDSMVLMNKGVEMELERVLKVFTVIDFSGNKFEGEIPKSIGLLKEL 820

  Fly   821 HIFDLPQN---------------LSWLDLSHNKIY-HLPFANLVKVKSLKYVDLTNNSLEDVPAS 869
            |:.:|..|               |..||:|.||:. .:| ..|.|:..|.|::.::|.|
plant   821 HVLNLSNNALSGHIASSMGNLMALESLDVSQNKLSGEIP-QELGKLTYLAYMNFSHNQL------ 878

  Fly   870 IVGSMRNGSQVLLAGNPLHCGCNARPLKYFMLQQTIAGEDLKSIYCGTPALIKDKQLISLDDEYL 934
             ||.:..|:|                   |..|:..:.||...:|  .|:|.|...:.....:..
plant   879 -VGLLPGGTQ-------------------FQTQKCSSFEDNHGLY--GPSLEKICDIHGKTPQQS 921

  Fly   935 HCA----EDEQEMYKGI 947
            ..|    |||:|:...|
plant   922 DMAPEPEEDEEEVISWI 938

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
conv	NP_001286416.1	leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	150..175	CDD:275380
		leucine-rich repeat	176..199	CDD:275380	5/16 (31%)
		LRR_8	198..258	CDD:290566	19/59 (32%)
		leucine-rich repeat	200..223	CDD:275380	7/22 (32%)
		LRR_RI	201..545	CDD:238064	112/410 (27%)
		leucine-rich repeat	224..271	CDD:275380	15/62 (24%)
		LRR_8	245..306	CDD:290566	22/79 (28%)
		leucine-rich repeat	272..295	CDD:275380	8/24 (33%)
		LRR_8	296..354	CDD:290566	16/64 (25%)
		leucine-rich repeat	296..319	CDD:275380	8/28 (29%)
		LRR_8	322..401	CDD:290566	23/80 (29%)
		leucine-rich repeat	322..343	CDD:275380	6/21 (29%)
		leucine-rich repeat	344..367	CDD:275380	6/22 (27%)
		leucine-rich repeat	371..390	CDD:275380	6/18 (33%)
		leucine-rich repeat	391..414	CDD:275380	11/33 (33%)
		leucine-rich repeat	416..438	CDD:275380	5/21 (24%)
		LRR_8	437..495	CDD:290566	18/76 (24%)
		leucine-rich repeat	439..462	CDD:275380	9/40 (23%)
		leucine-rich repeat	463..486	CDD:275380	6/23 (26%)
		LRR_RI	486..738	CDD:238064	77/276 (28%)
		LRR_8	486..545	CDD:290566	23/69 (33%)
		leucine-rich repeat	487..510	CDD:275380	10/28 (36%)
		leucine-rich repeat	511..534	CDD:275380	7/24 (29%)
		leucine-rich repeat	535..554	CDD:275380	5/21 (24%)
		LRR_8	554..614	CDD:290566	16/62 (26%)
		leucine-rich repeat	555..578	CDD:275380	7/25 (28%)
		leucine-rich repeat	579..603	CDD:275380	6/23 (26%)
		leucine-rich repeat	604..627	CDD:275380	5/22 (23%)
		LRR_8	626..710	CDD:290566	27/94 (29%)
		leucine-rich repeat	628..649	CDD:275380	6/20 (30%)
		leucine-rich repeat	652..672	CDD:275380	5/19 (26%)
		LRR_8	698..765	CDD:290566	21/70 (30%)
		leucine-rich repeat	700..726	CDD:275380	7/25 (28%)
		leucine-rich repeat	727..745	CDD:275380	5/17 (29%)
		LRR_8	777..839	CDD:290566	25/132 (19%)
		leucine-rich repeat	779..802	CDD:275380	8/23 (35%)
		leucine-rich repeat	829..852	CDD:275380	9/23 (39%)
RLP19	NP_179112.1	PLN00113	3..>646	CDD:331614	158/588 (27%)
		leucine-rich repeat	114..137	CDD:275380	7/22 (32%)
		leucine-rich repeat	138..161	CDD:275380	7/22 (32%)
		leucine-rich repeat	162..185	CDD:275380	5/22 (23%)
		leucine-rich repeat	186..209	CDD:275380	4/22 (18%)
		leucine-rich repeat	210..233	CDD:275380	8/22 (36%)
		leucine-rich repeat	234..257	CDD:275380	5/22 (23%)
		leucine-rich repeat	258..281	CDD:275380	6/23 (26%)
		leucine-rich repeat	282..305	CDD:275380	6/22 (27%)
		leucine-rich repeat	306..329	CDD:275380	7/22 (32%)
		leucine-rich repeat	330..351	CDD:275380	7/20 (35%)
		leucine-rich repeat	354..377	CDD:275380	6/22 (27%)
		leucine-rich repeat	378..402	CDD:275380	7/27 (26%)
		leucine-rich repeat	403..424	CDD:275380	3/20 (15%)
		leucine-rich repeat	427..451	CDD:275380	6/23 (26%)
		leucine-rich repeat	452..477	CDD:275380	9/25 (36%)
		leucine-rich repeat	507..526	CDD:275380	4/18 (22%)
		leucine-rich repeat	527..550	CDD:275380	5/22 (23%)
		leucine-rich repeat	551..574	CDD:275380	9/36 (25%)
		leucine-rich repeat	575..604	CDD:275380	10/36 (28%)
		PLN00113	<604..692	CDD:331614	29/105 (28%)
		leucine-rich repeat	605..630	CDD:275380	6/32 (19%)
		leucine-rich repeat	631..655	CDD:275380	10/26 (38%)
		PLN00113	<656..739	CDD:331614	29/95 (31%)
		leucine-rich repeat	656..676	CDD:275380	6/22 (27%)
		leucine-rich repeat	677..700	CDD:275380	9/26 (35%)
		leucine-rich repeat	701..722	CDD:275380	4/26 (15%)
		leucine-rich repeat	723..795	CDD:275380	14/71 (20%)
		leucine-rich repeat	796..819	CDD:275380	1/22 (5%)
		PLN00113	<808..962	CDD:331614	36/160 (23%)
		leucine-rich repeat	820..843	CDD:275380	3/22 (14%)
		leucine-rich repeat	844..867	CDD:275380	9/23 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000