DRSC/TRiP Functional Genomics Resources

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Protein Alignment conv and Lrrc15

DIOPT Version :9

Sequence 1:NP_001286416.1 Gene:conv / 36588 FlyBaseID:FBgn0261269 Length:1092 Species:Drosophila melanogaster
Sequence 2:NP_083249.1 Gene:Lrrc15 / 74488 MGIID:1921738 Length:579 Species:Mus musculus


Alignment Length:592 Identity:144/592 - (24%)
Similarity:248/592 - (41%) Gaps:124/592 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   435 NMTGLKVLNASYNSITEIPKNCFPKLYELHTIDVSHNNISSIFNGVFQTLFSLRSIDLSHNSMRE 499
            |...|::||   ..|||:|::.|..:..|..:.:..|.:::|..|.|:.|.|||.:.|::|.::.
Mouse    54 NAMSLQILN---THITELPEDKFLNISALIALKMEKNELANIMPGAFRNLGSLRHLSLANNKLKN 115

  Fly   500 IKSSTFGTLPTLLEMDLSHNELVSVVRGSLAKLTSLRQLYLNNNQLEKL----FQLPISLNELYF 560
            :....|..:..|..:.||:|:||.:.....::.::|::|.|..|.||.:    |...:.|.:|..
Mouse   116 LPVRLFQDVNNLETLLLSNNQLVQIQPAQFSQFSNLKELQLYGNNLEYIPEGVFDHLVGLTKLNL 180

  Fly   561 SHNRLTNIPSGTWPVMNSLIYLDLSHNQLGDTLNGESFTGLLVVQRLKLQNNGISQPPKDAVAVM 625
            .:|..|::....:..:.:|..|.|..|:|.|...| :|..|..:|.|.||.|.|...........
Mouse   181 GNNGFTHLSPRVFQHLGNLQVLRLYENRLSDIPMG-TFDALGNLQELALQENQIGTLSPGLFHNN 244

  Fly   626 STLQYLHLENNNITTLERSAFGKLPVLFELNLYGNQVKDISKRAFEGLLQLLTLNLSSNGIQTLQ 690
            ..||.|:|.||:|:.|....|.:||.|.:|.|:||.:|::|.                       
Mouse   245 RNLQRLYLSNNHISHLPPGIFMQLPHLNKLTLFGNSLKELSP----------------------- 286

  Fly   691 NDIFVGLPSLRNLDLSFNSLTKL-DNKTNGVLDDLLSLETLDLSHNRISFVTKKTFPSHQYIPYN 754
             .:|..:|:||.|.|..|.:|.| ||    ....|..|:.|.||||::|:::...|....    |
Mouse   287 -GVFGPMPNLRELWLYNNHITSLPDN----AFSHLNQLQVLILSHNQLSYISPGAFNGLT----N 342

  Fly   755 LRNLNLSYNLMPILTYDITFGTKKLVRLDVSHNQINDLRRGVISNFTSLQSLDMS-YNELSNLKS 818
            ||.|:|..|                                      :||.||.: :..|:||::
Mouse   343 LRELSLHTN--------------------------------------ALQDLDGNVFRSLANLRN 369

  Fly   819 EEHIFDLPQNLSWLDLSHNKIYHLPFANLVKVKSLKYVDLTNNSLEDVPASIVGSMRNGSQVLLA 883
                         :.|.:|::..||.:....|..|..:.|.||:||::|..|...:.|..::.|.
Mouse   370 -------------VSLQNNRLRQLPGSIFANVNGLMTIQLQNNNLENLPLGIFDHLGNLCELRLY 421

  Fly   884 GNPLHCGCNARPL-KYFMLQQTIAGEDLKSIYCGTPALIKDKQLISLDDEYLHCAEDEQEMYKGI 947
            .||..|..|..|| .:.:|.:...|.|...: |.:||.::.:.|:.::..:...:....|..:  
Mouse   422 DNPWRCDSNILPLHDWLILNRARLGTDTLPV-CSSPASVRGQSLVIINVNFPGPSVQGPETPE-- 483

  Fly   948 DYEQLTDVRFREVKTNKAGMLTLCWYVSGFSDVSDFHVYIR-SSSNDVLHQSDYAYNNRTAQIPV 1011
                                      ||.:.|.|.:..... ||:.::...:|..|.:.....|:
Mouse   484 --------------------------VSSYPDTSSYPDSTSISSTTEITRSTDDDYTDLNTIEPI 522

  Fly  1012 EELSTLG 1018
            ::.:|.|
Mouse   523 DDRNTWG 529

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
convNP_001286416.1 leucine-rich repeat 125..148 CDD:275380
leucine-rich repeat 150..175 CDD:275380
leucine-rich repeat 176..199 CDD:275380
LRR_8 198..258 CDD:290566
leucine-rich repeat 200..223 CDD:275380
LRR_RI 201..545 CDD:238064 31/109 (28%)
leucine-rich repeat 224..271 CDD:275380
LRR_8 245..306 CDD:290566
leucine-rich repeat 272..295 CDD:275380
LRR_8 296..354 CDD:290566
leucine-rich repeat 296..319 CDD:275380
LRR_8 322..401 CDD:290566
leucine-rich repeat 322..343 CDD:275380
leucine-rich repeat 344..367 CDD:275380
leucine-rich repeat 371..390 CDD:275380
leucine-rich repeat 391..414 CDD:275380
leucine-rich repeat 416..438 CDD:275380 1/2 (50%)
LRR_8 437..495 CDD:290566 18/57 (32%)
leucine-rich repeat 439..462 CDD:275380 8/22 (36%)
leucine-rich repeat 463..486 CDD:275380 6/22 (27%)
LRR_RI 486..738 CDD:238064 74/256 (29%)
LRR_8 486..545 CDD:290566 16/58 (28%)
leucine-rich repeat 487..510 CDD:275380 5/22 (23%)
leucine-rich repeat 511..534 CDD:275380 6/22 (27%)
leucine-rich repeat 535..554 CDD:275380 7/22 (32%)
LRR_8 554..614 CDD:290566 18/59 (31%)
leucine-rich repeat 555..578 CDD:275380 4/22 (18%)
leucine-rich repeat 579..603 CDD:275380 9/23 (39%)
leucine-rich repeat 604..627 CDD:275380 6/22 (27%)
LRR_8 626..710 CDD:290566 25/83 (30%)
leucine-rich repeat 628..649 CDD:275380 9/20 (45%)
leucine-rich repeat 652..672 CDD:275380 7/19 (37%)
LRR_8 698..765 CDD:290566 25/67 (37%)
leucine-rich repeat 700..726 CDD:275380 10/26 (38%)
leucine-rich repeat 727..745 CDD:275380 7/17 (41%)
LRR_8 777..839 CDD:290566 9/62 (15%)
leucine-rich repeat 779..802 CDD:275380 0/22 (0%)
leucine-rich repeat 829..852 CDD:275380 5/22 (23%)
Lrrc15NP_083249.1 LRR 1 54..75 9/23 (39%)
leucine-rich repeat 58..78 CDD:275380 8/22 (36%)
LRR 2 78..99 5/20 (25%)
PLN00113 82..>401 CDD:215061 103/402 (26%)
LRR 3 102..123 6/20 (30%)
leucine-rich repeat 103..126 CDD:275380 5/22 (23%)
LRR 4 126..147 6/20 (30%)
leucine-rich repeat 127..150 CDD:275380 6/22 (27%)
LRR 5 150..171 7/20 (35%)
leucine-rich repeat 151..174 CDD:275380 7/22 (32%)
LRR 6 174..195 4/20 (20%)
leucine-rich repeat 175..198 CDD:275380 4/22 (18%)
LRR 7 198..219 8/21 (38%)
leucine-rich repeat 199..222 CDD:275380 9/23 (39%)
LRR 8 222..243 6/20 (30%)
leucine-rich repeat 223..246 CDD:275380 6/22 (27%)
LRR 9 246..267 9/20 (45%)
leucine-rich repeat 247..270 CDD:275380 10/22 (45%)
LRR 10 270..291 8/44 (18%)
leucine-rich repeat 271..294 CDD:275380 8/46 (17%)
LRR 11 294..315 9/24 (38%)
leucine-rich repeat 295..318 CDD:275380 10/26 (38%)
LRR 12 318..339 8/20 (40%)
leucine-rich repeat 319..342 CDD:275380 8/26 (31%)
LRR 13 342..363 10/58 (17%)
leucine-rich repeat 343..364 CDD:275380 9/58 (16%)
LRR 14 366..387 6/33 (18%)
leucine-rich repeat 367..387 CDD:275380 5/32 (16%)
LRR 15 390..411 8/20 (40%)
leucine-rich repeat 391..412 CDD:275380 8/20 (40%)
LRRCT 423..>462 CDD:214507 12/39 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 476..509 7/60 (12%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm42484
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.910

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