Protein Alignment conv and Lrrc17

DIOPT Version :10

• Sequence 1: NP_610948.2
• Gene: conv / 36588
• FlyBaseID: FBgn0261269
• Length: 1092
• Species: Drosophila melanogaster
• Sequence 2: NP_001020326.1
• Gene: Lrrc17 / 502715
• RGDID: 1560165
• Length: 446
• Species: Rattus norvegicus
• Alignment Length: 443
• Identity: 101/443 - (22%)
• Similarity: 165/443 - (37%)
• Gaps: 160/443 - (36%)

  Fly   325 LARNRLKKIEFQMFTQMNYVELLDLAENNITKIEKNSFKDIYQAIINVSHNALELIETAAFENCV 389
            ||||:::.::..||::...::.|||.:|.|:|||..:|..:.:
  Rat    93 LARNKIRVLKNNMFSKFKRLKSLDLQQNEISKIESEAFFGLNK---------------------- 135

  Fly   390 NITVLDLSHNRLANFSRRSFDETTFATYFQLSYNNLTNLAQIPIQNMTGLKVLNASYNSITEIPK 454
             :|.|.|.||::...:...|..|...:|.:| |:|                            |.
  Rat   136 -LTTLLLQHNQIKVLTEEVFIYTPLLSYLRL-YDN----------------------------PW 170

  Fly   455 NCFPKLYELHTIDVSHNNISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTFGTLPTLLEMDLSHN 519
            :|..:|                     :||.|:..|..:.|.....|.   |:.|.|      .|
  Rat   171 HCACEL---------------------ETLVSMLQIPRNRNLGNYAKC---GSPPAL------RN 205

  Fly   520 ELVSVVRGSLAKLTSLR-QLYLNNNQLEKLFQLPISLNELYFSHNRLTNIPSGTWPVMNSLIYLD 583
            :          ||..|: |...:..:.|:|..:|           :::.:|:...|..:|    .
  Rat   206 K----------KLLQLKPQELCDEEEKERLDPIP-----------QVSGVPAVIRPEADS----T 245

  Fly   584 LSHNQLGDTLNGESFTGLLVVQRLKLQNNGISQPPKDAVAVMSTLQYLHLENNNITTLERSAFGK 648
            |.||.            :..:|.|..:...:.:.|                 |||.
  Rat   246 LCHNY------------VFPIQTLDCKRKELKKVP-----------------NNIP--------- 272

  Fly   649 LPVLFELNLYGNQVKDISKRAFEGLLQLLTLNLSSNGIQTLQNDIFVGLPSLRNLDLSFNSLTKL 713
             |.:.:|:|..|::..:..:.||.:.:|..|||||||::.:....|:||..|..||||.|||...
  Rat   273 -PNIVKLDLSYNKISQLRPKEFEDVHELKKLNLSSNGLEFIDPAAFLGLIHLEELDLSNNSLQSF 336

  Fly   714 DNKTNGVLDDLLSLETLDLSHN--RISFVTKKTFPSHQYIPYNLR-NLNLSYN 763
            |   .|||:||..|:.|.|..|  |..:       |..|:.|.|: :.|:.||
  Rat   337 D---YGVLEDLYFLKLLWLRDNPWRCDY-------SIHYLYYWLKHHYNVHYN 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conv	NP_610948.2	leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	150..175	CDD:275380
		leucine-rich repeat	176..199	CDD:275380
		PPP1R42	191..359	CDD:455733	13/33 (39%)
		LRR_8	198..258	CDD:404697
		leucine-rich repeat	200..223	CDD:275380
		leucine-rich repeat	224..271	CDD:275380
		leucine-rich repeat	272..295	CDD:275380
		leucine-rich repeat	296..319	CDD:275380
		leucine-rich repeat	322..343	CDD:275380	6/17 (35%)
		leucine-rich repeat	344..367	CDD:275380	9/22 (41%)
		LRR	346..718	CDD:443914	78/372 (21%)
		leucine-rich repeat	371..390	CDD:275380	0/18 (0%)
		leucine-rich repeat	391..414	CDD:275380	7/22 (32%)
		leucine-rich repeat	416..438	CDD:275380	4/21 (19%)
		leucine-rich repeat	439..462	CDD:275380	3/22 (14%)
		leucine-rich repeat	463..486	CDD:275380	2/22 (9%)
		leucine-rich repeat	487..510	CDD:275380	4/22 (18%)
		leucine-rich repeat	511..534	CDD:275380	4/22 (18%)
		leucine-rich repeat	535..554	CDD:275380	5/19 (26%)
		leucine-rich repeat	555..578	CDD:275380	2/22 (9%)
		leucine-rich repeat	579..603	CDD:275380	3/23 (13%)
		leucine-rich repeat	604..627	CDD:275380	3/22 (14%)
		leucine-rich repeat	628..649	CDD:275380	3/20 (15%)
		PPP1R42	631..849	CDD:455733	46/136 (34%)
		leucine-rich repeat	652..672	CDD:275380	4/19 (21%)
		leucine-rich repeat	700..726	CDD:275380	14/25 (56%)
		leucine-rich repeat	727..745	CDD:275380	5/19 (26%)
		leucine-rich repeat	779..802	CDD:275380
		leucine-rich repeat	829..852	CDD:275380
Lrrc17	NP_001020326.1	leucine-rich repeat	68..86	CDD:275380
		LRR	<89..>356	CDD:443914	92/411 (22%)
		leucine-rich repeat	89..111	CDD:275380	6/17 (35%)
		leucine-rich repeat	112..135	CDD:275380	9/22 (41%)
		leucine-rich repeat	136..159	CDD:275380	7/22 (32%)
		PCC	141..>247	CDD:188093	32/189 (17%)
		leucine-rich repeat	160..210	CDD:275380	19/118 (16%)
		leucine-rich repeat	211..274	CDD:275380	17/116 (15%)
		leucine-rich repeat	275..298	CDD:275380	5/22 (23%)
		leucine-rich repeat	299..322	CDD:275380	11/22 (50%)
		leucine-rich repeat	323..346	CDD:275380	14/25 (56%)