DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment conv and CG32055

DIOPT Version :9

Sequence 1:NP_001286416.1 Gene:conv / 36588 FlyBaseID:FBgn0261269 Length:1092 Species:Drosophila melanogaster
Sequence 2:NP_729599.1 Gene:CG32055 / 39188 FlyBaseID:FBgn0052055 Length:534 Species:Drosophila melanogaster


Alignment Length:608 Identity:158/608 - (25%)
Similarity:250/608 - (41%) Gaps:157/608 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   308 DIGRGTFGSIARIGTIDLARNRLKKIEFQMFTQMN-YVELLDLAENNITKIEKNSFKDIYQAIIN 371
            |:|.|::          |.|      |.:.|.|:| ||             .|| :|.:  .::|
  Fly    25 DLGNGSY----------LCR------EIESFEQLNRYV-------------GKN-WKSV--KVVN 57

  Fly   372 VSHNALELIETAAFENCVNITVLDLSHNRLANFSRRSFDETTFATYFQLSYNNLTNLAQIPIQNM 436
             .|..:|..|.........:..||||.:                       ..:| |.:..:|:.
  Fly    58 -EHTGIERAEDGELPGLSTLLQLDLSES-----------------------GGVT-LGEKGLQDF 97

  Fly   437 TGLKVLNASYNSITEIPKNCFPKLYELHTIDVSHNNISSIFNGVFQTLFSLRSIDLSHNSMREIK 501
            ..|:.||.::..:.|:....||...|:...|||:|:|.:|...:.....:|...:.|.|.:..|:
  Fly    98 KALQKLNLTHAQLDELKSEQFPNPSEMINFDVSYNDILAITTKLMSGFGNLVYANFSENLIAVIE 162

  Fly   502 SSTFGTLPTLLEMDLSHNELVSVVRGSLAKLTSLRQLYLNNNQLEKLFQ------LPISLNELYF 560
            .:.|..:..|..:||:.|...::..|..|   :||.|.::||.|.. ||      || .|.||:.
  Fly   163 PNAFRHMKNLRFLDLTTNYQENITLGENA---NLRFLSISNNNLRD-FQWCHLRVLP-KLEELHL 222

  Fly   561 SHNRLTNIPSGTWPVMNSLIYLDLSHNQLGDTLNGESFTGLLVVQRLKLQNNGISQPPKDAVAVM 625
            ..|.|.::..|.:..:.:|..|::|:|.|.:            ::|......|...|        
  Fly   223 HSNWLEHLDMGIFYALPNLRVLNVSNNNLFE------------IKRTLFMAPGEIAP-------- 267

  Fly   626 STLQYLHLENNNITTLERSAFGKLPVLFELNLYGNQVKDISKRAFEGLLQLLTLNLSSNGIQTLQ 690
              |:.|...:|.:..|:.|.|.:|..|..|||:.||:..|..|||.||..|.||:|..|.|..|.
  Fly   268 --LELLDYSSNIVKVLDDSVFCRLKKLRTLNLWLNQINRIHPRAFLGLSSLQTLHLQGNKISILP 330

  Fly   691 NDIFVGLPSLRNLDLSFNSLTKLDNKTNG--VLDDLLSLETLDLSHNRISFVTKKTFPSHQYIPY 753
            :|:|..|.:|..||||.|::.||..:..|  :|..|:   .||||:|.|:               
  Fly   331 DDVFANLTALEKLDLSKNNIQKLGLRVFGERILRKLI---YLDLSNNYIA--------------- 377

  Fly   754 NLRNLNLSYNLMPILTYDITFGTKKLVRLDVSHNQINDLRRGVISNFTSLQSLDMSYNELSNLKS 818
            :|..|.||  .||.:. ::.....:||.||:.          :.:....||.|.::.|.|..:..
  Fly   378 DLHPLALS--SMPFIK-ELRLRRNRLVSLDLR----------MFAPLRQLQLLTINENRLEEIDG 429

  Fly   819 EEHIFDLPQNLSWLDLSHNKIYHLPFANLVKVKSLKYVDLTNNSLEDVPASIVGSMRNGSQVLLA 883
            |  |.|....|:.|:|::|::..||     .:||      :.|.|:         :||   :.|.
  Fly   430 E--ILDTLDRLNHLELNNNRLTFLP-----DLKS------SQNLLQ---------LRN---ITLE 469

  Fly   884 GNPLHCGC--------NARPLKY 898
            |||..|.|        |.|.:.|
  Fly   470 GNPWQCLCLDEITSWLNGRHVSY 492

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
convNP_001286416.1 leucine-rich repeat 125..148 CDD:275380
leucine-rich repeat 150..175 CDD:275380
leucine-rich repeat 176..199 CDD:275380
LRR_8 198..258 CDD:290566
leucine-rich repeat 200..223 CDD:275380
LRR_RI 201..545 CDD:238064 54/237 (23%)
leucine-rich repeat 224..271 CDD:275380
LRR_8 245..306 CDD:290566
leucine-rich repeat 272..295 CDD:275380
LRR_8 296..354 CDD:290566 11/46 (24%)
leucine-rich repeat 296..319 CDD:275380 3/10 (30%)
LRR_8 322..401 CDD:290566 19/79 (24%)
leucine-rich repeat 322..343 CDD:275380 6/21 (29%)
leucine-rich repeat 344..367 CDD:275380 4/22 (18%)
leucine-rich repeat 371..390 CDD:275380 4/18 (22%)
leucine-rich repeat 391..414 CDD:275380 4/22 (18%)
leucine-rich repeat 416..438 CDD:275380 3/21 (14%)
LRR_8 437..495 CDD:290566 15/57 (26%)
leucine-rich repeat 439..462 CDD:275380 6/22 (27%)
leucine-rich repeat 463..486 CDD:275380 6/22 (27%)
LRR_RI 486..738 CDD:238064 80/259 (31%)
LRR_8 486..545 CDD:290566 16/58 (28%)
leucine-rich repeat 487..510 CDD:275380 5/22 (23%)
leucine-rich repeat 511..534 CDD:275380 6/22 (27%)
leucine-rich repeat 535..554 CDD:275380 10/24 (42%)
LRR_8 554..614 CDD:290566 12/59 (20%)
leucine-rich repeat 555..578 CDD:275380 6/22 (27%)
leucine-rich repeat 579..603 CDD:275380 5/23 (22%)
leucine-rich repeat 604..627 CDD:275380 3/22 (14%)
LRR_8 626..710 CDD:290566 35/83 (42%)
leucine-rich repeat 628..649 CDD:275380 6/20 (30%)
leucine-rich repeat 652..672 CDD:275380 10/19 (53%)
LRR_8 698..765 CDD:290566 21/68 (31%)
leucine-rich repeat 700..726 CDD:275380 11/27 (41%)
leucine-rich repeat 727..745 CDD:275380 6/17 (35%)
LRR_8 777..839 CDD:290566 16/61 (26%)
leucine-rich repeat 779..802 CDD:275380 4/22 (18%)
leucine-rich repeat 829..852 CDD:275380 6/22 (27%)
CG32055NP_729599.1 leucine-rich repeat 76..99 CDD:275380 7/46 (15%)
leucine-rich repeat 100..123 CDD:275380 6/22 (27%)
LRR_8 128..180 CDD:290566 14/51 (27%)
leucine-rich repeat 128..147 CDD:275380 6/18 (33%)
leucine-rich repeat 148..171 CDD:275380 5/22 (23%)
leucine-rich repeat 172..192 CDD:275380 6/22 (27%)
LRR_RI <187..400 CDD:238064 78/260 (30%)
LRR_8 192..251 CDD:290566 20/60 (33%)
leucine-rich repeat 193..216 CDD:275380 10/24 (42%)
leucine-rich repeat 217..240 CDD:275380 6/22 (27%)
leucine-rich repeat 241..267 CDD:275380 7/37 (19%)
leucine-rich repeat 268..291 CDD:275380 7/22 (32%)
LRR_8 290..350 CDD:290566 28/59 (47%)
leucine-rich repeat 292..315 CDD:275380 12/22 (55%)
leucine-rich repeat 316..339 CDD:275380 10/22 (45%)
LRR_8 340..400 CDD:290566 23/80 (29%)
leucine-rich repeat 340..365 CDD:275380 10/24 (42%)
leucine-rich repeat 366..389 CDD:275380 12/42 (29%)
leucine-rich repeat 390..413 CDD:275380 4/33 (12%)
LRR_8 391..448 CDD:290566 16/69 (23%)
leucine-rich repeat 414..437 CDD:275380 8/24 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BJN8
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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