Protein Alignment conv and Con

DIOPT Version :10

• Sequence 1: NP_610948.2
• Gene: conv / 36588
• FlyBaseID: FBgn0261269
• Length: 1092
• Species: Drosophila melanogaster
• Sequence 2: NP_523930.3
• Gene: Con / 38590
• FlyBaseID: FBgn0005775
• Length: 691
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 131/565 - (23%)
• Similarity: 230/565 - (40%)
• Gaps: 135/565 - (23%)

  Fly   459 KLYELHTIDVSHNNISSIFNGVFQTLFSLRSIDLSHNSMREIKSSTFGTLPTLLEMDLSHNELVS 523
            :|.||..:..::..:..|...:.:.|.:|.||.:.::.:..:||..|..||.|..:.|::|.:::
  Fly   157 RLRELKFVIQNNARLDYIPTMIIEPLKNLSSIVIEYSQVEIVKSYAFANLPFLERIILNNNHIMA 221

  Fly   524 VVRGSLAKLTSLRQLYLNNNQLEKLFQ-----LPISLNELYFSHNRLTNIPSGTWPVMNSLIYLD 583
            :.:.:.|....||:|.|.:||:.::.:     ||: ...|:.::|.::.:..|.:..|..|.:|:
  Fly   222 LDQDAFANHIRLRELNLEHNQIFEMDRYAFRNLPL-CERLFLNNNNISTLHEGLFADMARLTFLN 285

  Fly   584 LSHNQLGDTLNGESFTGLLVVQRLKLQNNGISQPPKDAVAVMSTLQYLHLENNNITTLERSAFGK 648
            |:|||: :.|..|.|.||                        ..|..|.|..||:..:..:.|.:
  Fly   286 LAHNQI-NVLTSEIFRGL------------------------GNLNVLKLTRNNLNFIGDTVFAE 325

  Fly   649 LPVLFELNLYGNQVKDISKRAFEGLLQLLTLNLSSNGIQTLQNDIFVGLPSLRNLDLSFNSLTKL 713
            |..|.||.|..|:::.||:||.:||..|.||||.:|.::.:.|.:..|.|:|.::::..|
  Fly   326 LWSLSELELDDNRIERISERALDGLNTLKTLNLRNNLLKKIDNGLLRGTPALLSINVQAN----- 385

  Fly   714 DNKTNGVLDDLLSLETLDLSHNRISFVTKKTFPSHQYIPYNLRNLNLSYNLMPILTYDITFGTKK 778
                        .||||             ||.:.|.|..||.|                 .|.:
  Fly   386 ------------KLETL-------------TFYTFQPIMDNLVN-----------------STSE 408

  Fly   779 LVRLDVSHNQ-INDLRRGVISNFTSLQSLDMSYNELSNLKSEEHIFDLPQNLSWLDLSHNKIYHL 842
            |:   ||.|: |.|.|         ||.:....|...:|:..:.:.||...|....||| .:..:
  Fly   409 LL---VSDNKFICDCR---------LQWIFELKNRTRHLQLRDSLEDLHCTLQEPKLSH-FVDPV 460

  Fly   843 P--FANLVKVKSLKYVDLTNNSLEDVPASIVGSMRNGSQVLLAGNPLHCGCNARPL----KYF-- 899
            |  ..:::.:.....:...:.|:..|..|:|||..:|  :.:..:..|.|..:|..    :.|
  Fly   461 PPTILDVLNIGGFTAIGSNSASMGGVGNSVVGSSYSG--LTMDDSRKHLGSRSRQALRGQRQFAS 523

  Fly   900 --------------MLQQTIAGEDLKSIYCGTPALIKDKQLISLDDEYLHCAEDEQEMYKGIDYE 950
                          ..|:.:..:||.::   .||   .|:....||.     .....:..|:|.:
  Fly   524 SAENVVESKMRRRRKRQEEVKEKDLAAV---APA---HKRYDYYDDN-----NGGMSLGHGLDLD 577

  Fly   951 QLTDVRFREVKTNKAGMLTLCWYVSGFSDVSDFHVYIRSSSNDVL 995
            .       .:..:|.|.......|.|.:|| |..:...|:|.|.|
  Fly   578 D-------NLSLHKQGFYGAGSPVVGHNDV-DVLMTSHSASGDAL 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
conv	NP_610948.2	leucine-rich repeat	125..148	CDD:275380
		leucine-rich repeat	150..175	CDD:275380
		leucine-rich repeat	176..199	CDD:275380
		PPP1R42	191..359	CDD:455733
		LRR_8	198..258	CDD:404697
		leucine-rich repeat	200..223	CDD:275380
		leucine-rich repeat	224..271	CDD:275380
		leucine-rich repeat	272..295	CDD:275380
		leucine-rich repeat	296..319	CDD:275380
		leucine-rich repeat	322..343	CDD:275380
		leucine-rich repeat	344..367	CDD:275380
		LRR	346..718	CDD:443914	69/263 (26%)
		leucine-rich repeat	371..390	CDD:275380
		leucine-rich repeat	391..414	CDD:275380
		leucine-rich repeat	416..438	CDD:275380
		leucine-rich repeat	439..462	CDD:275380	1/2 (50%)
		leucine-rich repeat	463..486	CDD:275380	3/22 (14%)
		leucine-rich repeat	487..510	CDD:275380	7/22 (32%)
		leucine-rich repeat	511..534	CDD:275380	4/22 (18%)
		leucine-rich repeat	535..554	CDD:275380	8/23 (35%)
		leucine-rich repeat	555..578	CDD:275380	4/22 (18%)
		leucine-rich repeat	579..603	CDD:275380	11/23 (48%)
		leucine-rich repeat	604..627	CDD:275380	0/22 (0%)
		leucine-rich repeat	628..649	CDD:275380	6/20 (30%)
		PPP1R42	631..849	CDD:455733	58/220 (26%)
		leucine-rich repeat	652..672	CDD:275380	9/19 (47%)
		leucine-rich repeat	700..726	CDD:275380	2/25 (8%)
		leucine-rich repeat	727..745	CDD:275380	4/17 (24%)
		leucine-rich repeat	779..802	CDD:275380	7/23 (30%)
		leucine-rich repeat	829..852	CDD:275380	5/24 (21%)
Con	NP_523930.3	LRR	<157..459	CDD:443914	98/387 (25%)
		leucine-rich repeat	185..208	CDD:275380	7/22 (32%)
		leucine-rich repeat	209..232	CDD:275380	4/22 (18%)
		leucine-rich repeat	233..256	CDD:275380	7/22 (32%)
		leucine-rich repeat	257..280	CDD:275380	4/22 (18%)
		leucine-rich repeat	281..304	CDD:275380	11/47 (23%)
		leucine-rich repeat	305..328	CDD:275380	7/22 (32%)
		leucine-rich repeat	329..352	CDD:275380	11/22 (50%)
		leucine-rich repeat	353..376	CDD:275380	8/22 (36%)